Rejuran Dual Effect Ampoule

Rejuran Dual Effect Ampoule

Efficacy100/100IrritancyMedium

Works for

Evens skin tone
Niacinamide, Arbutin + 1 more
Works well
What the product description says
“Niacinamide: Refines pores, absorbs oil, and improves the look of dark spots.”
Source: Sephora

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: arbutin, glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.7–2%
ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~0.3–0.55%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.55–0.8%
Anti-aging
Niacinamide, Adenosine + 2 more
Works well
What the product description says
“Promotes collagen and reduces the appearance of wrinkles.”
Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: serine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.7–2%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.6%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.95–1.15%
Moisturizing
Niacinamide, Ceramide np + 15 more
Works well
What the product description says
“Squalane: Lightweight moisture that softens and locks in hydration.”
Source: Sephora

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, urea

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.7–2%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.4–0.6%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.3–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.6–0.9%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.45–0.65%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.6%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.3–0.6%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.6%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%
Peg-6· HumectantEffect: LowHelps to dissolve other ingredients and attract water to the upper layer of the skin~5.2–6.4%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.9–2.4%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.45–0.65%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.35–0.65%
Oleic acid· EmollientEffect: LowHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness~0.25–0.5%
AlginEffect: LowUsed to thicken product formulation. Can help attract water to the upper layer of the skin~0.15–0.3%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.95–1.15%
Anti-blemish
Not advertised by the brand · Niacinamide, Aloe barbadensis leaf juice
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.7–2%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.95–1.15%
Anti-oxidation
Not advertised by the brand · Arbutin, Vaccinium angustifolium fruit extract + 5 more
May help

This product contains antioxidants (arbutin) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~0.3–0.55%
Vaccinium angustifolium fruit extractEffect: LowA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking~1.1–1.4%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.55–0.8%
Calendula officinalis flower extractEffect: LowA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating~0.55–0.85%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.6%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.55%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.25–0.45%

Can it cause trouble?

Irritancy
1 strong irritant: Calendula officinalis flower extract
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~0.55–0.85%est.
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.1–0.2%est.
1,2-hexanediolA preservativeMedium~0.7–1.05%est.
Vaccinium angustifolium fruit extractA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lackingMedium~1.1–1.4%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.95–1.15%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.55–0.8%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.45–0.65%est.
EthylhexylglycerinA preservativeMedium~0.4–0.6%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.35–0.6%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.35–0.65%est.
ArbutinBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutinMedium~0.3–0.55%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.
Oleic acidHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin drynessMedium~0.25–0.5%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
AlginUsed to thicken product formulation. Can help attract water to the upper layer of the skin3/5~0.15–0.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Peg-6~5.2–6.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to dissolve other ingredients and attract water to the upper layer of the skin

More about Peg-6
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Rubus fruticosus leaf extract~3.1–3.8%
Formula
Dipropylene glycol~2.2–2.7%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Butylene glycol~1.9–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Niacinamide~1.7–2%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
1,2-hexanediol~0.7–1.05%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Vaccinium angustifolium fruit extract~1.1–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking

More about Vaccinium angustifolium fruit extract
Aloe barbadensis leaf juice~0.95–1.15%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialAnti-inflammatoryReduces rednessReduces irritationAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Carbomer~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Calendula officinalis flower extract~0.55–0.85%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Morus fruit extract
Not recognized
Glycyrrhiza glabra root extract~0.55–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Squalane~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Hydrolyzed dna~0.5–0.75%
Formula
Irritation risk
Low
More about Hydrolyzed dna
Xanthan gum~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hydrogenated lecithin~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Sodium hyaluronate~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Caprylyl glycol~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.4–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Polysorbate 20~0.4–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Hexylene glycol~0.35–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Ceramide np~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Adenosine~0.3–0.6%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Urea~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Trehalose~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Pentylene glycol~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Arbutin~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin

More about Arbutin
Tocopheryl acetate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Bisabolol~0.25–0.45%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Cholesterol~0.3–0.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Serine~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Oleic acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
CleansingAnti-inflammatoryMoisturizing

Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness

More about Oleic acid
Inulin lauryl carbamate~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing
More about Inulin lauryl carbamate
Algin~0.15–0.3%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Used to thicken product formulation. Can help attract water to the upper layer of the skin

More about Algin
Disodium phosphate~0.15–0.25%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Glyceryl polyacrylate~0.1–0.2%
Formula
Irritation risk
Low

Helps to create a nice product texture and spread the product more easily on the skin

More about Glyceryl polyacrylate
Pullulan~0.1–0.2%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Potassium phosphate~0.1–0.15%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Ingredient list view

Water, Peg-6, Glycerin, Rubus fruticosus leaf extract, Dipropylene glycol, Butylene glycol, Niacinamide, 1,2-hexanediol, Vaccinium angustifolium fruit extract, Aloe barbadensis leaf juice, Carbomer, Calendula officinalis flower extract, Unknown, Glycyrrhiza glabra root extract, Squalane, Hydrolyzed dna, Xanthan gum, Hydrogenated lecithin, Sodium hyaluronate, Caprylyl glycol, Ethylhexylglycerin, Polysorbate 20, Hexylene glycol, Ceramide np, Adenosine, Urea, Trehalose, Pentylene glycol, Arbutin, Tocopheryl acetate, Bisabolol, Cholesterol, Serine, Oleic acid, Inulin lauryl carbamate, Algin, Disodium phosphate, Glyceryl polyacrylate, Pullulan, Potassium phosphate

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 11/5 15:22 GMT
$55.00
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Sephora
$55.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
RejuranDual Effect AmpouleYOUR PRODUCTAHCHydrating Korean Skincare Aqualuronic Face SerumFULLightRe:dence Hyaluron Ectoin SerumEqqualberryVitamin illuminating Serum
Match—93%86%84%
Price$55.00$25.96−$29.04$12.06−$42.94$18.10−$36.90
Shared key ingredients—9 of 138 of 138 of 13
Key difference—Copper Tripeptide-1Copper Tripeptide-1Ferulic Acid
Irritancy Medium Medium Medium Medium
Drying alcohol————
View product Shop Shop Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 22 studies and safety reviews.

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As an Amazon Associate, WIMJ earns from qualifying purchases.