PharmaClinix Lightenex Cream

PharmaClinix Lightenex Cream

Efficacy62/100IrritancyMedium
Edit

Works for

1 of 2 advertised claims delivered

Moisturizing
10 ingredients credited for this claim
Good support
What the product description says
“The nourishing formula ensures that skin is hydrated with a soft and smooth texture.”
Source: Face the future

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: imperata cylindrica root extract, aloe barbadensis extract.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

Carthamus tinctorius seed oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and might help calm down inflammation~0.3–0.75%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.5–1.2%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.95–1.45%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~0.15–0.55%
Imperata cylindrica root extractKey active· HumectantEffect: HighA plat extract that might help neutralize free radicals in skin and attract water to its upper layer~0.5–1.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.45–1.05%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~1.1–1.7%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.4–0.9%
Aloe barbadensis extract· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.1–0.3%
Evens skin tone
1 ingredient credited for this claim
Limited support
What the product description says
“Lighten hyperpigmentation and maintain a clear skin tone with PharmaClinix Lightenex Cream 50ml, now available at Face the Future Advanced Skin Clinic and Online Shop.”
Source: Face the future

This product contains ingredients (glycyrrhiza glabra root extract) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.5–1.1%
Anti-oxidation
Not advertised by the brand · 7 ingredients credited for this claim
Strong support

This product contains antioxidants (tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - imperata cylindrica root extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

TocopherolKey activeEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Imperata cylindrica root extractKey activeEffect: MediumA plat extract that might help neutralize free radicals in skin and attract water to its upper layer~0.5–1.1%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~1.8–2.7%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.5–1.1%
Carthamus tinctorius seed oilEffect: LowAn emollient that helps soften the skin and might help calm down inflammation~0.3–0.75%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.5–1.2%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~1.4–2.1%
Anti-aging
Not advertised by the brand · 3 ingredients credited for this claim
Moderate support

This product contains tocopherol. This ingredient help neutralize free radicals in skin. By doing so, they might be able to prevent early signs of aging (like fine lines and wrinkles), at least to some extent. These ingredients will not be able to "reverse" signs of aging.

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.5–1.2%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.2–1.8%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~1.4–2.1%

Can it cause trouble?

Irritancy
2 strong irritants: Mitracarpus scaber extract, Rosa gallica flower extract
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Mitracarpus scaber extractUsed for its fragrance. Has some anti-bacterial properties. Can be irritatingHigh~4.6–7%est.
Rosa gallica flower extract—High~0.2–0.8%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~3.6–5.4%est.
Imperata cylindrica root extractA plat extract that might help neutralize free radicals in skin and attract water to its upper layerMedium~2.7–4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~1.8–2.7%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~1.4–2.1%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.95–1.45%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.4–0.9%est.
Daucus carota sativa extract—Medium~0.1–0.4%est.
Aloe barbadensis extractTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.1–0.3%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.5–1.2%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.4–0.9%est.
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~0.15–0.55%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Kojic dipalmitate~22–33%
Formula
Arctostaphylos uva ursi leaf extract~5.1–7.7%
Formula
Mitracarpus scaber extract~4.6–7%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Used for its fragrance. Has some anti-bacterial properties. Can be irritating

More about Mitracarpus scaber extract
Glycyrrhiza glabra root extract~3.6–5.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Imperata cylindrica root extract~2.7–4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plat extract that might help neutralize free radicals in skin and attract water to its upper layer

More about Imperata cylindrica root extract
Tocopheryl acetate~1.8–2.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ascorbyl palmitate~1.4–2.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Tocopherol~1.2–1.8%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Cetyl palmitate~1.1–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Caprylic/capric triglyceride~0.95–1.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycyrrhiza glabra root extract~0.5–1.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Imperata cylindrica root extract~0.5–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plat extract that might help neutralize free radicals in skin and attract water to its upper layer

More about Imperata cylindrica root extract
Butyrospermum parkii butter~0.5–1.2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Dimethicone~0.45–1.05%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Isopropyl palmitate~0.4–0.9%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Rosa gallica flower extract~0.2–0.8%
Irritant · high
Carthamus tinctorius seed oil~0.3–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the skin and might help calm down inflammation

More about Carthamus tinctorius seed oil
Prunus amygdalus dulcis bud extract~0.15–0.55%
Formula
Arachis hypogaea oil~0.1–0.5%
Formula
Daucus carota sativa extract~0.1–0.4%
Irritant · medium
Isopropyl myristate~0.15–0.55%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Aloe barbadensis extract~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis extract
Ingredient list view

Kojic dipalmitate, Arctostaphylos uva ursi leaf extract, Mitracarpus scaber extract, Glycyrrhiza glabra root extract, Imperata cylindrica root extract, Tocopheryl acetate, Ascorbyl palmitate, Tocopherol, Cetyl palmitate, Caprylic/capric triglyceride, Glycyrrhiza glabra root extract, Imperata cylindrica root extract, Butyrospermum parkii butter, Dimethicone, Isopropyl palmitate, Rosa gallica flower extract, Carthamus tinctorius seed oil, Prunus amygdalus dulcis bud extract, Arachis hypogaea oil, Daucus carota sativa extract, Isopropyl myristate, Aloe barbadensis extract

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.

  1. 1
  2. 2
    Vitamin E in dermatologyncbi.nlm.nih.gov
  3. 3
    Vitamin E and Skin Healthlpi.oregonstate.edu
  4. 4
  5. 5
  6. 6
PharmaClinix Lightenex Cream
PharmaClinixLightenex Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.