Peter Thomas Roth Peptide Skinjection Amplified Wrinkle-Fix Serum
Works for
Anti-agingAcetyl hexapeptide-8, Pentapeptide-18 + 3 moreMay help
“PETER THOMAS ROTH CLINICAL SKIN CARE PEPTIDE SKINJECTION™ Amplified Wrinkle-Fix Serum is a non-invasive, dual-purpose treatment that visibly helps to reduce the appearance of expression lines and prevent the look of future wrinkles.”
This product contains acetyl hexapeptide-8, n-prolyl palmitoyl tripeptide-56 acetate, palmitoyl tripeptide-38, pentapeptide-18. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
MoisturizingSide benefit · Acetyl hexapeptide-8, Pentapeptide-18 + 19 moreWorks well
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, n-prolyl palmitoyl tripeptide-56 acetate, palmitoyl tripeptide-38, pentapeptide-18
Can it cause trouble?
Irritancy9 flagged ingredientsMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Dimethicone~6.2–7.6%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeSqualane~4.5–5.5%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneButylene glycol~3.1–3.8%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolGlycerin~2.4–3%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPolysilicone-11~2–2.5%
- Irritation risk
- Low
A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel
More about Polysilicone-11Silica~1.8–2.3%
Acetyl hexapeptide-8~1.4–1.7%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Pentapeptide-18~1.2–1.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Pentapeptide-18N-prolyl palmitoyl tripeptide-56 acetate~0.95–1.2%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about N-prolyl palmitoyl tripeptide-56 acetatePalmitoyl tripeptide-38~0.7–1.05%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-38Hydrolyzed vegetable protein~0.6–0.9%
Sodium hyaluronate~0.55–0.8%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateTocopherol~0.5–0.75%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolPhytosterols~0.5–0.8%
- Irritation risk
- Medium
Lipids that work as an emollient and can be helpful in repairing skin barrier function
More about PhytosterolsHydrogenated lecithin~0.5–0.7%
- Irritation risk
- Low
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
More about Hydrogenated lecithinLeuconostoc/radish root ferment filtrate~0.45–0.7%
- Irritation risk
- Medium
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine
More about Leuconostoc/radish root ferment filtrateCitric acid~0.4–0.6%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidCaprylic/capric triglyceride~0.45–0.7%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglyceridePolyglyceryl-10 myristate~0.3–0.6%
- Irritation risk
- Low
Pentylene glycol~0.35–0.65%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolCaprylyl glycol~0.3–0.6%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolSodium benzoate~0.3–0.5%
Sodium phytate~0.25–0.5%
Sodium hydroxide~0.3–0.5%
Potassium sorbate~0.25–0.5%
Ethylhexyl palmitate~0.3–0.55%
- Irritation risk
- Low
- Comedogenicity
- 3/5
An emollient that helps soften the skin and create a nice product texture
More about Ethylhexyl palmitateHydroxypropyl cyclodextrin~0.3–0.55%
- Irritation risk
- Medium
Used to stabilize product formulations and help soften the upper layer of the skin
More about Hydroxypropyl cyclodextrinTrihydroxystearin~0.25–0.45%
- Irritation risk
- Low
Helps soften the upper layer of the skin and improve the product texture
More about TrihydroxystearinGlucomannan~0.25–0.4%
- Irritation risk
- Low
Ethylhexylglycerin~0.2–0.4%
Ammonium acryloyldimethyltaurate/vp copolymer~0.2–0.4%
- Irritation risk
- Low
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
More about Ammonium acryloyldimethyltaurate/vp copolymerGlyceryl stearate~0.25–0.45%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateStearyl alcohol~0.2–0.4%
- Irritation risk
- Low
An emollient that helps soften the skin
More about Stearyl alcoholBehenyl alcohol~0.2–0.4%
- Irritation risk
- Low
Non-drying alcohol that helps water and oil mix together. Also serves as an emollient
More about Behenyl alcoholCarbomer~0.1–0.2%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerMica~0.1–0.2%
- Irritation risk
- Low
Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light
More about MicaPhenoxyethanol~0.15–0.25%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIngredient list view
Water, Dimethicone, Squalane, Butylene glycol, Glycerin, Polysilicone-11, Silica, Acetyl hexapeptide-8, Pentapeptide-18, N-prolyl palmitoyl tripeptide-56 acetate, Palmitoyl tripeptide-38, Hydrolyzed vegetable protein, Sodium hyaluronate, Tocopherol, Phytosterols, Hydrogenated lecithin, Leuconostoc/radish root ferment filtrate, Citric acid, Caprylic/capric triglyceride, Polyglyceryl-10 myristate, Pentylene glycol, Caprylyl glycol, Sodium benzoate, Sodium phytate, Sodium hydroxide, Potassium sorbate, Ethylhexyl palmitate, Hydroxypropyl cyclodextrin, Trihydroxystearin, Glucomannan, Ethylhexylglycerin, Ammonium acryloyldimethyltaurate/vp copolymer, Glyceryl stearate, Stearyl alcohol, Behenyl alcohol, Carbomer, Mica, Phenoxyethanol
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Peter Thomas RothPeptide Skinjection Amplified Wrinkle-Fix SerumYOUR PRODUCT | Medik8Liquid Peptides | Eveline CosmeticsConcentrated Formula Lifting | Beauty PieSuperdrops Flash Face Lift Intense | |
|---|---|---|---|---|
| Match | — | 57% | 53% | 53% |
| Price | $61.00 | $68.00+$7.00 | — | $49.00−$12.00 |
| Shared key ingredients | — | 5 of 12 | 5 of 12 | 5 of 12 |
| Key difference | — | Copper Palmitoyl Heptapeptide-14 | Palmitoyl Tetrapeptide-7 | Kappaphycus Alvarezii Extract |
| Irritancy | Medium | Low | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: OARS + ALPS Overnight Renewal SerumThe Ordinary Multi-Peptide + HA Serum
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 7 studies and safety reviews.
- 1
- 2Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 3
- 4Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 5
- 6Vitamin E in dermatologyncbi.nlm.nih.gov
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