Works for:
based on ingredients and %- Anti-aging
- Evens skin tone
- Anti-oxidation
- Exfoliation
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 3
Key actives
Anti-aging
What does the product description say?
Perricone MD presents the Thio Plex Intensive 2-Step Brightening System; an innovative, multi-tasking two-part treatment that utilises advanced ingredients with exceptional potency to deliver superior brightening and anti-aging results.
Source: Skinstore
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: tocotrienols.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Might be helpful in restoring skin barrier function and, when combined with zinc carbonate and malonic acid, reducing fine lines and wrinkles by stimulating elastin production. Also helps stabilize the product formulation
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Anti-oxidation
This product contains antioxidants (glutathione, thioctic acid, tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Evens skin tone
What does the product description say?
The duo of treatments work synergistically to transform dull and ageing skin, helping to minimise the look of discoloration and unveil a more even, refined tone.
Source: Skinstore
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, glycolic acid
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Moisturizing
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A silicone that mixes with water creating nice light-weight product texture
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Helps soften the upper layer of the skin
Helps soften the upper layer of the skin and create a thicker product consistency
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps preserve products and creates a nice product texture
A silicone that serves as an emollient. Helps create a nice non-greasy feels
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
Potential irritants
Comedogenic ingredients
User reviews (0)
Averages from community submissions.
No reviews yet for this product.
Be the first to share your experience!
Tried this product?
Help capture what the ingredient list can't—texture, finish, pilling, scent, and more. Answer what you can, skip the rest.
Takes ~30 seconds.
Reviews are shown in aggregate. No personal details.
| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Perricone MD Thio-Plex 2-Step Treatment | Current | - | |
NuFace Lifter Vitamin C and Hyaluronic Acid Serum S3 | 53% | $84.00 | |
Elizabeth Arden PREVAGE Anti-Aging Intensive Repair Daily Serum | 53% | $107.90 | |
 Collistar Anti-Dark Spot Concentrate Glycolic Acid and Niacinamide | 51% | $24.00 | |
 U Beauty The Barrier Bioactive Treatment | 51% | $186.00 | |
 Clinique DDMID Hydrating Jelly + Uneven Texure Concentrate | 51% | $43.00 |
Key Actives
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A type of clay that consists mainly of aluminum silicate. Helps absorb oil and creates a thicker product consistency. Can be used to add a white color
A silicone that mixes with water creating nice light-weight product texture
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Produces temporary toning effect. Can help dissolve other ingredients or preserve products
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
An aromatic blend of unspecified and possibly irritating ingredients
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
Used to help evenly disperse other ingredients (for example, pigment) in a formulation. Can create a temporary tightening effect on the skin
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Helps preserve products and creates a nice product texture
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Helps soften the upper layer of the skin and create a thicker product consistency
Helps oil and water mix together. Has some emollient properties
Helps preserve products and creates a nice product texture
Comedogenic ingredients
Helps soften the upper layer of the skin and create a thicker product consistency
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps oil and water mix together. Has some emollient properties
All ingredients
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A type of clay that consists mainly of aluminum silicate. Helps absorb oil and creates a thicker product consistency. Can be used to add a white color
Might be helpful in restoring skin barrier function and, when combined with zinc carbonate and malonic acid, reducing fine lines and wrinkles by stimulating elastin production. Also helps stabilize the product formulation
Used to help evenly disperse other ingredients (for example, pigment) in a formulation. Can create a temporary tightening effect on the skin
An aromatic blend of unspecified and possibly irritating ingredients
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Produces temporary toning effect. Can help dissolve other ingredients or preserve products
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A silicone that mixes with water creating nice light-weight product texture
Helps preserve products and creates a nice product texture
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A preservative. It helps prevent bacterial growth in cosmetic products
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Helps soften the upper layer of the skin and create a thicker product consistency
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps oil and water mix together. Has some emollient properties
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Helps preserve products and creates a nice product texture
A silicone that serves as an emollient. Helps create a nice non-greasy feels
A preservative. It helps prevent bacterial growth in cosmetic products
An aromatic blend of unspecified and possibly irritating ingredients
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Ingredient list view
Water, Glutathione, Kaolin, Magnesium aluminum silicate, Aluminum chlorohydrate, Disodium edta, Parfum, Glyceryl stearate, Alcohol denat., Dimethyl mea, Phosphatidylcholine, Thioctic acid, Ascorbyl palmitate, Ascorbyl glucoside, Glycolic acid, Xanthan gum, Camellia sinensis leaf extract, Colloidal silver, Peg/ppg-18/18 dimethicone, Caprylyl glycol, Glycerin, Phenoxyethanol, Sorbic acid, Limonene, Water, Ascorbyl palmitate, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Tocotrienols, Tocopherol, Sodium hyaluronate, Disodium edta, Ceteareth-20, Dimethicone, Cyclopentasiloxane, Caprylyl glycol, Cyclohexasiloxane, Zinc sulfate, Elaeis guineensis oil, Phenoxyethanol, Sorbic acid, Parfum, Limonene, Linalool, Citral
- Glutathione as a skin whitening agent: Facts, myths, evidence and controversies
- Glutathione for skin lightening: a regnant myth or evidence-based verity?
- Glutathione for skin lightening for dermatologists and cosmetologists
- Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate, sodium magnesium silicate, zirconium silicate, attapulgite, bentonite, Fuller's earth, hectorite, kaolin, lithium magnesium silicate, lithium magnesium sodium silicate, montmorillonite, pyrophyllite, and zeolite
- Extracellular matrix in cutaneous ageing: the effects of 0.1% copper-zinc malonate-containing cream on elastin biosynthesis
- Scientific Committee on Consumer Safety:OPINION ON the safety of aluminium in cosmetic products
- The Roles of Vitamin C in Skin Health
- Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Glycerol and the skin: holistic approach to its origin and functions
- Final Report on the Safety Assessment of Isopropyl Isostearate
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside study
- Tocotrienols: Vitamin E beyond tocopherols
- Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)
- Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Zinc Salts as Used in Cosmetics
- Genetic Architecture of Palm Oil Fatty Acid Composition in Cultivated Oil Palm (Elaeis guineensis Jacq.) Compared to Its Wild Relative E. oleifera (H.B.K) Cortés
- Nutrient composition of Nigerian palm kernel from the dura and tenera varieties of the oil palm (Elaeis guineensis)