Perricone MD Neuropeptide Pro-Strength Firming Moisturizer
Works for
2 of 3 advertised claims delivered
Moisturizing14 ingredients credited for this claimStrong support
“Neuropeptide Pro-Strength Firming Moisturizer”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, salvia hispanica seed oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np
Anti-aging2 ingredients credited for this claimModerate support
“Neuropeptides: Protein-like messenger molecules reduce the look of stubborn expression lines and deep creases by supporting visible skin renewal for a relaxed, smooth appearance.”
This product contains acetyl hexapeptide-8. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Evens skin toneNo ingredient credited for this claimNo support
“Simultaneously correcting visible photodamage, discoloration and dark spots, it promotes a more even-toned, resilient appearance over time.”
Effective ingredients missing or their concentration is too low
Anti-oxidationNot advertised by the brand · 3 ingredients credited for this claimStrong support
This product contains antioxidants (tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy5 strong irritants: Parfum, Citronellol + 3 more — patch-test recommendedHigh risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Caprylic/capric triglyceride~5.9–7.2%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglyceridePolyhydroxystearic acid~4.2–5.2%
- Irritation risk
- Medium
Used to create a thicker product consistency and stabilize the formulation
More about Polyhydroxystearic acidTriethoxycaprylylsilane~3.3–4%
- Irritation risk
- Low
A type of silicone that helps oil and water mix well together. Helps to disperse other ingredients, e.g. pigments, evenly in a formulation
More about TriethoxycaprylylsilaneCoco-caprylate/caprate~2.6–3.1%
- Irritation risk
- Low
Helps to soften the upper layer of the skin without creating a greasy texture
More about Coco-caprylate/caprateTocopherol~2–2.5%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolGlycerin~1.8–2.2%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinSteareth-20~1.5–1.8%
Sorbitan stearate~1.2–1.4%
Cetearyl alcohol~1–1.3%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholPolysorbate 60~0.7–1.05%
C12-15 alkyl benzoate~0.6–0.9%
- Irritation risk
- Low
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
More about C12-15 alkyl benzoateTocopheryl acetate~0.55–0.8%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetatePolyester-7~0.5–0.75%
- Irritation risk
- Low
Neopentyl glycol diheptanoate~0.45–0.7%
- Irritation risk
- Low
Helps soften the upper layer of the skin and create a nice product consistency
More about Neopentyl glycol diheptanoateMethylglucoside phosphate~0.45–0.65%
- Irritation risk
- Low
Copper lysinate/prolinate~0.4–0.65%
- Irritation risk
- Low
Palmitoyl glycine~0.5–0.7%
- Irritation risk
- Low
Bisabolol~0.3–0.55%
- Irritation risk
- Low
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
More about BisabololGlyceryl stearate~0.4–0.6%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateBenzyl alcohol~0.3–0.5%
- Irritation risk
- High
A preservative. Can be used to mask unpleasant smell. Can be irritating
More about Benzyl alcoholCaprylyl glycol~0.35–0.6%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycol1,2-hexanediol~0.3–0.5%
Linum usitatissimum seed oil~0.25–0.45%
Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer~0.3–0.55%
- Irritation risk
- Medium
Used to stabilize product formulations
More about Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymerSodium citrate~0.3–0.5%
- Irritation risk
- Medium
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products
More about Sodium citratePongamia pinnata seed extract~0.3–0.55%
- Irritation risk
- Low
Salvia hispanica seed oil~0.3–0.55%
- Irritation risk
- Low
Chia seed oil. Helps to soften the upper layer of the skin and might be helpful in repairing skin barrier
More about Salvia hispanica seed oilMacadamia ternifolia seed oil~0.3–0.6%
- Irritation risk
- Medium
Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients
More about Macadamia ternifolia seed oilParfum~0.25–0.5%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumSclerotium gum~0.25–0.5%
- Irritation risk
- Low
Used to create gel-like formulas and stabilize emulsions
More about Sclerotium gumCeramide np~0.3–0.6%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npCitric acid~0.3–0.5%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidPhenoxyethanol~0.3–0.55%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolPotassium sorbate~0.3–0.55%
Acetic acid~0.25–0.5%
- Irritation risk
- Low
Acetyl hexapeptide-8~0.25–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8S-palmitoylglutathione~0.25–0.5%
- Irritation risk
- Low
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.25–0.5%
- Irritation risk
- Low
Used to increase stability of product formulations
More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamateSodium hydroxide~0.25–0.45%
Sodium phytate~0.25–0.45%
Citronellol~0.2–0.35%
Geranyl acetate~0.15–0.3%
- Irritation risk
- Low
Hydroxycitronellal~0.15–0.25%
- Irritation risk
- High
A fragrance. A likely allergen and can be irritating
More about HydroxycitronellalLimonene~0.15–0.3%
- Irritation risk
- High
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
More about LimoneneLinalool~0.15–0.25%
Linalyl acetate~0.1–0.2%
- Irritation risk
- Low
Tetramethyl acetyloctahydronaphthalenes~0.1–0.15%
- Irritation risk
- Low
Ingredient list view
Water, Caprylic/capric triglyceride, Polyhydroxystearic acid, Triethoxycaprylylsilane, Coco-caprylate/caprate, Tocopherol, Glycerin, Steareth-20, Sorbitan stearate, Cetearyl alcohol, Polysorbate 60, C12-15 alkyl benzoate, Tocopheryl acetate, Polyester-7, Neopentyl glycol diheptanoate, Methylglucoside phosphate, Copper lysinate/prolinate, Palmitoyl glycine, Bisabolol, Glyceryl stearate, Benzyl alcohol, Caprylyl glycol, 1,2-hexanediol, Linum usitatissimum seed oil, Ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer, Sodium citrate, Pongamia pinnata seed extract, Salvia hispanica seed oil, Macadamia ternifolia seed oil, Parfum, Sclerotium gum, Ceramide np, Citric acid, Phenoxyethanol, Potassium sorbate, Acetic acid, Acetyl hexapeptide-8, S-palmitoylglutathione, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Sodium hydroxide, Sodium phytate, Citronellol, Geranyl acetate, Hydroxycitronellal, Limonene, Linalool, Linalyl acetate, Tetramethyl acetyloctahydronaphthalenes
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDNeuropeptide Pro-Strength Firming MoisturizerYOUR PRODUCT | Allies of SkinRetinal 0.1% & Peptides Advanced Repair Night Cream | VT CosmeticsPDRN Reedle Shot Cream 50ml | NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream | |
|---|---|---|---|---|
| Match | — | 62% | 61% | 61% |
| Price | $132.30 | — | $74.10−$58.20 | $39.59−$92.71 |
| Shared key ingredients | — | 6 of 7 | 5 of 7 | 5 of 7 |
| Key difference | — | Madecassoside | Tripeptide-1 | Copper Tripeptide-1 |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
- 1Safety Assessment of Alkyl Esters as Used in Cosmeticscir-safety.org
- 2Vitamin E in dermatologyncbi.nlm.nih.gov
- 3Vitamin E and Skin Healthlpi.oregonstate.edu
- 4
- 5
- 6
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