Perricone MD

Perricone MD Neuropeptide Pore-Refining & Resurfacing Cream Cleanser

Name: Perricone MD - Neuropeptide Pore-Refining & Resurfacing Cream Cleanser
Brand: Perricone MD

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Cleansing

Sodium cocoyl glutamate, Cocamidopropyl hydroxysultaine + 13 more

Cleanses gently

What the product description says

“Neuropeptide Pore-Refining & Resurfacing Cream Cleanser”

Source: Face the future

This product works by removing dirt and oil from the surface of the skin. It uses a combination of mild cleansing agents (carbomer, ceteareth-25, ceteareth-6, cocamidopropyl hydroxysultaine, coco-glucoside, decyl glucoside, glyceryl stearate, glycol distearate, hexylene glycol, peg-60 almond glycerides, sodium cocoyl glutamate, sodium olivate, stearyl alcohol, xanthan gum) and should be able to cleanse the skin gently. Still keep in mind that any cleansing can disrupt the skin barrier, and most people do not need to cleanse their skin more than once per day.

Even though this formulation is mild, the following cleansing agents could trigger an irritation or allergy for some people: coco-glucoside, decyl glucoside

Sodium cocoyl glutamateEffect: HighHelps oil and water mix together~9.2–11.3%

Cocamidopropyl hydroxysultaineEffect: HighUsed as a cleansing agent. Helps water and oil mix together~5.9–7.3%

Decyl glucosideEffect: HighHelps oil and water mix together. Can be irritating~2.4–3%

Sodium olivateEffect: High~1.6–1.9%

Glycol distearateEffect: HighHelps water and oil mix together~1.5–1.8%

Ceteareth-25Effect: HighHelps oil and water mix together~0.4–0.6%

Coco-glucosideEffect: HighUsed as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating~0.35–0.65%

Hexylene glycolEffect: HighHelps create a more spreadable product texture~0.35–0.6%

Xanthan gumEffect: HighUsed to create a thicker product consistency~0.3–0.55%

Ceteareth-6Effect: High~0.3–0.55%

Glyceryl stearateEffect: HighAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.6%

Peg-60 almond glyceridesEffect: High~0.3–0.55%

Stearyl alcoholEffect: HighAn emollient that helps soften the skin~0.3–0.5%

CarbomerEffect: HighHelps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations~0.25–0.5%

LecithinEffect: High, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.6%

Exfoliation

Glycolic acid, Lactobionic acid + 2 more

Works well

What the product description says

“Gently exfoliates to improve skin texture and clarity”

Source: Face the future

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid, lactobionic acid, salicylic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~3.2–3.9%

Lactobionic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity~0.6–0.85%

Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.25–0.5%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Anti-blemish

Side benefit · Salicylic acid, Glycolic acid + 4 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: salicylic acid. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycolic acid, lactobionic acid

Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.25–0.5%

Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~3.2–3.9%

Lactobionic acidKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity~0.6–0.85%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.3–0.55%

Oleanolic acidUnder-dosedMight be helpful against blemishes, work as an anti-oxidant, reduce inflammation and improve skin's ability to hold on to moisture, but more research is needed to confirm its effectiveness when applied topically to human skin~0.25–0.5%

Can it cause trouble?

Irritancy

2 strong irritants: Parfum, Limonene

Medium risk

We flagged 22 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~3.2–3.9%est.

Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~2.4–3%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.25–0.45%est.

Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.25–0.5%est.

Coco-glucosideUsed as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritatingHigh~0.35–0.65%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.15%est.

Sodium cocoyl glutamateHelps oil and water mix togetherMedium~9.2–11.3%est.

Cocamidopropyl hydroxysultaineUsed as a cleansing agent. Helps water and oil mix togetherMedium~5.9–7.3%est.

Glycol distearateHelps water and oil mix togetherMedium~1.5–1.8%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~1–1.2%est.

Lactobionic acidA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticityMedium~0.6–0.85%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–0.75%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.45–0.65%est.

EthylhexylglycerinA preservativeMedium~0.4–0.6%est.

Hexylene glycolHelps create a more spreadable product textureMedium~0.35–0.6%est.

Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.25–0.5%est.

Ceteareth-25Helps oil and water mix togetherMedium~0.4–0.6%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.6%est.

Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.25–0.5%est.

Nordihydroguaiaretic acidUsed to stabilize the formula of product formulation. Might be helpful in neutralizing free radicals in skinMedium~0.25–0.5%est.

Sodium metabisulfiteA preservativeMedium~0.1–0.2%est.

Potassium sorbateA preservativeMedium~0.2–0.4%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.7–2.1%est.

Alternatives

Cheaper, or higher on efficacy

Skinfix Acne+ 2% BHA Cleanser

Cheaper72% match

$10.00

Community Sixty-Six Detoxifying AHA/BHA Gel Cleanser

Cheaper72% match

$15.82

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Sodium cocoyl glutamate~9.2–11.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium cocoyl glutamate

Cocamidopropyl hydroxysultaine~5.9–7.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used as a cleansing agent. Helps water and oil mix together

More about Cocamidopropyl hydroxysultaine

Glycolic acid~3.2–3.9%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid

Decyl glucoside~2.4–3%

Irritant · high

Irritation risk: High

Works for

Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside

Glycerin~2–2.4%

Formula

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Butyrospermum parkii butter~1.7–2.1%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Glycol distearate~1.5–1.8%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Glycol distearate

Sodium olivate~1.6–1.9%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sodium olivate

Acrylates/c10-30 alkyl acrylate crosspolymer~1–1.2%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Trehalose~0.7–1.05%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose

Lactobionic acid~0.6–0.85%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-agingEvens skin toneMoisturizingAnti-oxidationExfoliationAnti-inflammatoryAnti-blemish

A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity

More about Lactobionic acid

Sodium hydroxide~0.55–0.8%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Phenoxyethanol~0.5–0.75%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Sodium chloride~0.5–0.75%

Formula

Irritation risk: Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride

Caprylyl glycol~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Citric acid~0.45–0.65%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Ethylhexylglycerin~0.4–0.6%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Hexylene glycol~0.35–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol

Polyquaternium-73~0.35–0.65%

Formula

Irritation risk: Low

More about Polyquaternium-73

Allantoin~0.3–0.55%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Niacinamide~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Dipotassium glycyrrhizate~0.25–0.5%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Parfum~0.25–0.45%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Tetrasodium glutamate diacetate~0.25–0.5%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate

Butylene glycol~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Peg-60 almond glycerides~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Peg-60 almond glycerides

Salicylic acid~0.25–0.5%

Hero · Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-blemishExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid

Sodium hyaluronate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Malus domestica fruit cell culture extract~0.25–0.5%

Formula

Irritation risk: Low

More about Malus domestica fruit cell culture extract

Xanthan gum~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Glyceryl stearate~0.3–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Sodium citrate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate

Ceteareth-25~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Ceteareth-25

Caprylic/capric triglyceride~0.35–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Carbomer~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Lecithin~0.3–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Ceteareth-6~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Ceteareth-6

Coco-glucoside~0.35–0.65%

Irritant · high

Irritation risk: High

Works for

Cleansing

Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating

More about Coco-glucoside

Sodium lactate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate

Pterocarpus marsupium bark extract~0.25–0.45%

Formula

Irritation risk: Low

More about Pterocarpus marsupium bark extract

Nordihydroguaiaretic acid~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Used to stabilize the formula of product formulation. Might be helpful in neutralizing free radicals in skin

More about Nordihydroguaiaretic acid

Oleanolic acid~0.25–0.5%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-agingAnti-inflammatoryAnti-oxidation

Might be helpful against blemishes, work as an anti-oxidant, reduce inflammation and improve skin's ability to hold on to moisture, but more research is needed to confirm its effectiveness when applied topically to human skin

More about Oleanolic acid

Sodium metabisulfite~0.1–0.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sodium metabisulfite

Stearyl alcohol~0.3–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol

Potassium sorbate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Acetic acid~0.2–0.35%

Formula

Irritation risk: Low

More about Acetic acid

Acetyl hexapeptide-8~0.15–0.3%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Biotin~0.15–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Palmitoyl tripeptide-1~0.2–0.35%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7~0.2–0.35%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1~0.1–0.15%

Formula

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1

Limonene~0.05–0.15%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Ingredient list view

Water, Sodium cocoyl glutamate, Cocamidopropyl hydroxysultaine, Glycolic acid, Decyl glucoside, Glycerin, Butyrospermum parkii butter, Glycol distearate, Sodium olivate, Acrylates/c10-30 alkyl acrylate crosspolymer, Trehalose, Lactobionic acid, Sodium hydroxide, Phenoxyethanol, Sodium chloride, Caprylyl glycol, Citric acid, Ethylhexylglycerin, Hexylene glycol, Polyquaternium-73, Allantoin, Niacinamide, Dipotassium glycyrrhizate, Parfum, Tetrasodium glutamate diacetate, Butylene glycol, Peg-60 almond glycerides, Salicylic acid, Sodium hyaluronate, Malus domestica fruit cell culture extract, Xanthan gum, Glyceryl stearate, Sodium citrate, Ceteareth-25, Caprylic/capric triglyceride, Carbomer, Lecithin, Ceteareth-6, Coco-glucoside, Sodium lactate, Pterocarpus marsupium bark extract, Nordihydroguaiaretic acid, Oleanolic acid, Sodium metabisulfite, Stearyl alcohol, Potassium sorbate, Acetic acid, Acetyl hexapeptide-8, Biotin, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, Limonene

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Perricone MDNeuropeptide Pore-Refining & Resurfacing Cream CleanserYOUR PRODUCT	SkinfixAcne+ 2% BHA Cleanser	Community Sixty-SixDetoxifying AHA/BHA Gel Cleanser	CeraVeGel Moussant Anti-Imperfections
Match	—	72%	72%	70%
Price	—	$10.00	$15.82	—
Shared key ingredients	—	8 of 32	5 of 32	7 of 32
Key difference	—	Azelaic Acid	Panthenol	Lactic Acid
Irritancy	Medium	Low	Low	Low
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 32 studies and safety reviews.

1
Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmeticsncbi.nlm.nih.gov
2
Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patientsjournals.lww.com
3
Photoprotective and antiinflammatory effects of topical glycolic acidncbi.nlm.nih.gov
4
Glycolic acid peel therapy – a current reviewncbi.nlm.nih.gov
5
Dual Effects of Alpha-Hydroxy Acids on the Skinmdpi.com
6
Ecofriendly surfactant is allergen of the yearmdedge.com
7
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
8
Lactobionic acidmdedge.com
9
Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water lossonlinelibrary.wiley.com
10
Comparative evaluation of skin moisture after topical application of 10% and 30% lactobionic acidonlinelibrary.wiley.com
11
The use of polyhydroxy acids (PHAs) in photoaged skin
12
Profile of wound healing process induced by allantoinscielo.br
13
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
14
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
15
Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent modelresearchgate.net
16
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.ncbi.nlm.nih.gov
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Salicylic acid as a peeling agent: a comprehensive reviewncbi.nlm.nih.gov
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Beta Hydroxy Acidsfda.gov
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A review of toxicity from topical salicylic acid preparationssciencedirect.com
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Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Studyonlinelibrary.wiley.com
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Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
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Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
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Final Report on the Safety Assessment of Ceteareth-2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18,-20,-22,-23,-24,-25,-27, -28, -29, -30, -33, -34, -40, -50, -55, -60, -80, and -100journals.sagepub.com
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In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Responseresearchgate.net
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Allergen of the Year—Alkyl Glucosidepracticeupdate.com
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Nordihydroguaiaretic acid, an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes.dmd.aspetjournals.org
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Antimutagenic and antitumorigenic activities of nordihydroguaiaretic acidsciencedirect.com
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Estrogenic activity of an antioxidant, nordihydroguaiaretic acid (NDGA)sciencedirect.com
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Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: An updatencbi.nlm.nih.gov
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Effectiveness of the formulation that containing oleanolic acid 3% on inhibition of 5-α reductase activity on skin of patients with acnelongdom.org
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The effect of ursolic and oleanolic acids on human skin fibroblast cellsncbi.nlm.nih.gov
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Final report on the safety assessment of sodium sulfite, potassium sulfite, ammonium sulfite, sodium bisulfite, ammonium bisulfite, sodium metabisulfite and potassium metabisulfitencbi.nlm.nih.gov

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