Perricone MD - Neuropeptide Night Cream

Perricone MD Neuropeptide Night Cream

WORKS FOR
  • Anti-aging
  • Moisturizing
KEY INGREDIENTS
  • pentapeptide-18
  • dipeptide-2
  • acetyl hexapeptide-8
  • ceramide ng
  • palmitoyl hexapeptide-12
  • palmitoyl tetrapeptide-7
  • tetrapeptide-21
  • urea
  • allantoin
  • butyrospermum parkii butter
  • c10-18 triglycerides
  • c12-15 alkyl benzoate
  • cetearyl alcohol
  • dimethicone
  • dipotassium glycyrrhizate
  • fructose
  • glucose
  • glycerin
  • sodium hyaluronate
  • sodium lactate
  • sodium pca
  • squalane
  • trehalose
  • tyrosine
  • +21 more
PROMISES
FULFILLED
100 /100
IRRITANCY
HIGH
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In stock $204.54
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Formula review

See a mistake?
Promise
What does the product description say?
"Awake to smoother skin with Perricone MD Neuropeptide Night Cream , an anti-wrinkle treatment that works alongside the body’s natural repair cycle."
WIMJ summary

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, dipeptide-2, palmitoyl tetrapeptide-7, pentapeptide-18, tetrapeptide-21.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Ingredient Effectiveness Concentration Irritancy
HIGH
meets threshold
MEDIUM
meets threshold
MEDIUM
meets threshold
See a mistake?
Promise
What does the product description say?
"The silky formula uses DMAE to lift the appearance of sagging skin, replenishing vital moisture deep below the surface for a plumping and firming effect."
WIMJ summary

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: allantoin, fructose.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide ng, dipeptide-2, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, pentapeptide-18, tetrapeptide-21, urea

Ingredient Effectiveness Concentration Irritancy
HIGH
meets threshold
HIGH
meets threshold
HIGH
meets threshold

Potential irritants

Ingredients by volume

Ingredient Estimated concentration
Plain old water
45% - 55%
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
4.6% - 5.6%
Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness
4.1% - 5%
Used to create a nice product consistency while softening the upper layer of the skin
3.1% - 3.8%
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
2.3% - 2.8%
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
2% - 2.4%
Helps oil and water mix together
1.6% - 2%
Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin
1.4% - 1.7%
Helps soften the skin and attract water to its upper layer. Helps create nice product texture
1.2% - 1.5%
0.9% - 1.1%
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
0.65% - 1%
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
0.55% - 0.85%
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
0.55% - 0.85%
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
0.5% - 0.7%
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
0.5% - 0.75%
Is used to enhance product texture and can help to optically mask skin imperfections
0.45% - 0.7%
0.4% - 0.6%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.3% - 0.6%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.3% - 0.55%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.25% - 0.5%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.25% - 0.45%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.3% - 0.55%
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
0.25% - 0.45%
0.2% - 0.4%
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
0.25% - 0.45%
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
0.2% - 0.4%
Might help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation
0.25% - 0.4%
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
0.25% - 0.45%
Helps attract water to the upper layer of the skin
0.25% - 0.4%
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
0.2% - 0.4%
A sugar that attracts water to the upper layer of the skin
0.2% - 0.4%
0.2% - 0.4%
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
0.25% - 0.4%
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
0.2% - 0.4%
Can work as an exfoliant but is typically used to adjust the product pH
0.25% - 0.4%
Used to adjust the product's pH
0.25% - 0.4%
Stabilizes the product formulation
0.2% - 0.4%
Used to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentration
0.2% - 0.4%
Helps oil and water mix together
0.3% - 0.55%
Helps oil and water mix together
0.25% - 0.45%
Helps preserve products and creates a nice product texture
0.25% - 0.45%
Used to create a thicker product consistency and soften the upper layer of the skin
0.25% - 0.45%
Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating
0.25% - 0.5%
Used to preserve products, dissolve other ingredients and create a nice product texture
0.25% - 0.45%
Helps create a more spreadable product texture
0.2% - 0.35%
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
0.2% - 0.35%
0.3% - 0.55%
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
0.2% - 0.35%
Naturally present in skin and helps to attract water to its upper layer
0.15% - 0.3%
A preservative. It helps prevent bacterial growth in cosmetic products
0.15% - 0.25%
A preservative
0.15% - 0.3%
An aromatic blend of unspecified and possibly irritating ingredients
0.15% - 0.25%
A fragrance. Can be irritating
0.1% - 0.15%
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
0.1% - 0.15%

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