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Perricone MD Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream
Perricone MD

Perricone MD Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream

Efficacy87/100IrritancyMedium
See all ingredients 100% recommend: 1 review In 2 routines
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Works for

2 of 2 advertised claims delivered

Moisturizing
Cannabidiol - derived from extract or tincture or resin of cannabis, Glycerin + 21 more
Strong evidence
What the product description says
“Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: bis-diglyceryl polyacyladipate-2, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: cannabidiol - derived from extract or tincture or resin of cannabis

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–6.5%
Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.1–0.45%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.55–1.3%
Vitis vinifera seed oilKey active· EmollientEffect: HighA great emollient that can also have anti-oxidant properties~1.3–2%
Bis-diglyceryl polyacyladipate-2Key active· Emollient, OcclusiveEffect: HighHelps soften the upper layer of the skin and reduce water loss from its surface~1.8–2.7%
Cannabidiol - derived from extract or tincture or resin of cannabisHeroEffect: HighCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function~0.35–0.75%
Cannabis sativa seed oilKey active· EmollientEffect: HighA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer~0.4–0.9%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~0.2–0.75%
Hydrogenated palm kernel glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.9–1.35%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.5–2.2%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.1–3.1%
Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.1–0.35%
Hydrogenated palm glycerides· EmollientEffect: LowAn emollient that softens the skin~0.15–0.6%
Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.1–1.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.9–4.4%
Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.35–0.85%
Sodium lactateUnder-dosedEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.05–0.3%
Dipotassium glycyrrhizateUnder-dosedEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.6%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.6%
Sodium pcaUnder-dosedEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.05–0.2%
Lens esculenta fruit extractUnder-dosedEffect: MediumA plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lacking~0.1–0.35%
Pyrus malus fruit extractUnder-dosedEffect: MediumCan have some moisturizing properties due to its sugar content~0.15–0.55%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.5%
Anti-aging
Tocotrienols, Tocopherol
Moderate evidence
What the product description says
“CBD revitalises the look and feel of stressed and problematic skin for a healthy, youthful-looking appearance.”
Source: Allbeauty

This product contains tocotrienols. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

TocotrienolsKey activeEffect: MediumA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.1–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.5%
Anti-oxidation
Not advertised by the brand · Tocotrienols, Cannabidiol - derived from extract or tincture or resin of cannabis + 7 more
Strong evidence

This product contains antioxidants (tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

TocotrienolsKey activeEffect: HighA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.1–0.5%
Cannabidiol - derived from extract or tincture or resin of cannabisEffect: LowCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function~0.35–0.75%
Calendula officinalis flower extractEffect: LowA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating~0.4–0.9%
Vitis vinifera seed oilEffect: LowA great emollient that can also have anti-oxidant properties~1.3–2%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.5%
Citrullus lanatus fruit extractEffect: Low, below effective doseA plant extract that can contain an antioxidant compound~0.2–0.7%
Pyrus malus fruit extractEffect: Low, below effective doseCan have some moisturizing properties due to its sugar content~0.15–0.55%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.2–0.75%
Lens esculenta fruit extractEffect: Low, below effective doseA plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lacking~0.1–0.35%

Can it cause trouble?

Irritancy
14 flagged ingredients
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~0.4–0.9%est.
Aluminum starch octenylsuccinateUsed to thicken the product's consistencyMedium~2.7–4.1%est.
Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~1.3–2%est.
Cannabis sativa seed oilA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layerMedium~0.4–0.9%est.
Cannabidiol - derived from extract or tincture or resin of cannabisCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier functionMedium~0.35–0.75%est.
Citrullus lanatus fruit extractA plant extract that can contain an antioxidant compoundMedium~0.2–0.7%est.
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~0.15–0.55%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.1–0.45%est.
Caprylhydroxamic acidA preservativeMedium~0.1–0.4%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.15–0.65%est.
1,2-hexanediolA preservativeMedium~0.1–0.35%est.
Lens esculenta fruit extractA plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lackingMedium~0.1–0.35%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.05–0.3%est.
Potassium sorbateA preservativeMedium~0.05–0.2%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.1–3.1%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.1–0.45%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.15–0.65%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–6.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl stearate~2.9–4.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Aluminum starch octenylsuccinate~2.7–4.1%
Irritant · medium
Irritation risk
Medium

Used to thicken the product's consistency

More about Aluminum starch octenylsuccinate
Cetearyl alcohol~2.1–3.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Bis-diglyceryl polyacyladipate-2~1.8–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from its surface

More about Bis-diglyceryl polyacyladipate-2
Cetyl alcohol~1.5–2.2%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Vitis vinifera seed oil~1.3–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil
Dicaprylyl ether~1.1–1.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Hydrogenated palm kernel glycerides~0.9–1.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Hydrogenated palm kernel glycerides
Squalane~0.55–1.3%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Calendula officinalis flower extract~0.4–0.9%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Cannabis sativa seed oil~0.4–0.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Cannabidiol - derived from extract or tincture or resin of cannabis~0.35–0.75%
Hero · MoisturizingIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-blemishAnti-oxidation

CBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function

More about Cannabidiol - derived from extract or tincture or resin of cannabis
Glyceryl caprylate~0.35–0.85%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Bisabolol~0.2–0.75%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Ectoin~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Citrullus lanatus fruit extract~0.2–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can contain an antioxidant compound

More about Citrullus lanatus fruit extract
Allantoin~0.15–0.6%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces rednessAnti-blemishReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Dipotassium glycyrrhizate~0.15–0.6%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Xanthan gum~0.15–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Pyrus malus fruit extract~0.15–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Hydrogenated palm glycerides~0.15–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides
Tocotrienols~0.1–0.5%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols
Tocopherol~0.1–0.5%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Glycine soja oil~0.1–0.45%
Key activeComedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Caprylhydroxamic acid~0.1–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
Ceteareth-20~0.15–0.65%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
1,2-hexanediol~0.1–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Sodium polyacrylate~0.15–0.5%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Lens esculenta fruit extract~0.1–0.35%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lacking

More about Lens esculenta fruit extract
Sodium lactate~0.05–0.3%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Elaeis guineensis oil~0.1–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Sodium pca~0.05–0.2%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Potassium sorbate~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium benzoate~0.05–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Water, Glycerin, Glyceryl stearate, Aluminum starch octenylsuccinate, Cetearyl alcohol, Bis-diglyceryl polyacyladipate-2, Cetyl alcohol, Vitis vinifera seed oil, Dicaprylyl ether, Hydrogenated palm kernel glycerides, Squalane, Calendula officinalis flower extract, Cannabis sativa seed oil, Cannabidiol - derived from extract or tincture or resin of cannabis, Glyceryl caprylate, Bisabolol, Ectoin, Citrullus lanatus fruit extract, Allantoin, Dipotassium glycyrrhizate, Xanthan gum, Pyrus malus fruit extract, Hydrogenated palm glycerides, Tocotrienols, Tocopherol, Glycine soja oil, Caprylhydroxamic acid, Ceteareth-20, 1,2-hexanediol, Sodium polyacrylate, Lens esculenta fruit extract, Sodium lactate, Elaeis guineensis oil, Sodium pca, Potassium sorbate, Sodium benzoate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDHypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye CreamYOUR PRODUCTe.l.f. Cosmetics50 MG CBD Eye CreamDerma ESkin De-Stress Cheek & Eye Cream CorrectorMGC DermaEye Cream for Fine Lines and Wrinkles
Match—87%86%84%
Price$32.34——$53.34+$21.00
Shared key ingredients—5 of 153 of 153 of 15
Key difference—Dipeptide-2Camellia Sinensis Leaf Extract3-O-Ethyl Ascorbic Acid
Irritancy Medium Low Low Medium
Drying alcohol——— Contains drying alcohol
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Product summary

Based on the ingredients included, "Perricone MD - Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Perricone MD - Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream ticks this box. Glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Cannabis sativa seed oil, glycine soja oil, vitis vinifera seed oil, bis-diglyceryl polyacyladipate-2 and squalane in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We are excited that this moisturizer contains Cannabidiol, or CBD (0.35% - 0.75%). CBD is a new active in cosmetic products, and the studies on its effect in skin are still going on. CBD is one of the compounds in the cannabis plant. It does not have any psychotropic effects. When used topically, CBD can bind to skin cell receptors and "change their behavior". It can help reduce inflammation, itching, and help support skin barrier function. It also might be able to reduce acne.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, dipotassium glycyrrhizate and allantoin

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails from 36.00$ up to 72.00$ in the United States and from 24.40£ up to 1448.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 23 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Safety assessment of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmeticsncbi.nlm.nih.gov
  3. 3
    Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activitypdfs.semanticscholar.org
  4. 4
    The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)ncbi.nlm.nih.gov
  5. 5
    Final report on the safety assessment of Calendula officinalis extract and Calendula officinalisncbi.nlm.nih.gov
  6. 6
    Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 1: Achillea millefolium–Curcuma longaonlinelibrary.wiley.com
Perricone MD Hypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream
Perricone MDHypoallergenic CBD Sensitive Skin Therapy Soothing & Hydrating Eye Cream
Buy at Perricone MD$36.00Amazon

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Buy at Perricone MD$36.00Amazon

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