Perricone MD Hypoallergenic CBD Nourishing & Calming Moisturizer

Perricone MD Hypoallergenic CBD Nourishing & Calming Moisturizer

Efficacy75/100IrritancyMedium
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Works for

1 of 2 advertised claims delivered

Moisturizing
14 ingredients credited for this claim
Strong support
What the product description says
“Hypoallergenic CBD Nourishing & Calming Moisturizer”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: cannabis sativa seed oil, cetearyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: cannabidiol - derived from extract or tincture or resin of cannabis, ceramide np

Cannabidiol - derived from extract or tincture or resin of cannabisHeroEffect: HighCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function~0.2–0.8%
Cannabis sativa seed oilKey active· EmollientEffect: HighA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer~1.4–2%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.55%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~3.8–5.7%
Mauritia flexuosa fruit oilKey activeEffect: HighHelps soften the upper layer of the skin~0.45–1.05%
TriethylhexanoinKey activeEffect: HighHelps soften the upper layer of the skin~1.9–2.9%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–7.2%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1–1.5%
Coco-caprylateKey active· EmollientEffect: MediumAn emollient that softens skin and creates a nice product texture~2.8–4.2%
Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.4–0.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.55–1.3%
Dipotassium glycyrrhizateUnder-dosedEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.1–0.35%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.75%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%
Anti-aging
1 ingredient credited for this claim
Limited support
What the product description says
“CBD revitalizes the look and feel of stressed and problematic skin for a healthy, youthful-looking appearance.”
Source: Feelunique

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%

Can it cause trouble?

Irritancy
1 strong irritant: Calendula officinalis flower extract
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~1.4–2.1%est.
Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~2.8–4.2%est.
TriethylhexanoinHelps soften the upper layer of the skinMedium~1.9–2.9%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~1.6–2.4%est.
Cannabis sativa seed oilA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layerMedium~1.4–2%est.
Mauritia flexuosa fruit oilHelps soften the upper layer of the skinMedium~0.45–1.05%est.
Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~0.4–1%est.
Cannabidiol - derived from extract or tincture or resin of cannabisCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier functionMedium~0.2–0.8%est.
Caprylhydroxamic acidA preservativeMedium~0.05–0.2%est.
1,2-hexanediolA preservativeMedium~0.05–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1–1.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.8–7.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Betaine~3.8–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Coco-caprylate~2.8–4.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate
Triethylhexanoin~1.9–2.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Triethylhexanoin
Sodium acrylates copolymer~1.6–2.4%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Calendula officinalis flower extract~1.4–2.1%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Cannabis sativa seed oil~1.4–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Ceteareth-30~1.2–1.8%
Formula
Irritation risk
Low
Works for
Cleansing
More about Ceteareth-30
Cetearyl alcohol~1–1.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glyceryl stearate~0.55–1.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Mauritia flexuosa fruit oil~0.45–1.05%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Mauritia flexuosa fruit oil
Polyglyceryl-3 methylglucose distearate~0.4–1%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate
Glyceryl caprylate~0.4–0.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Cannabidiol - derived from extract or tincture or resin of cannabis~0.2–0.8%
Hero · MoisturizingIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-blemishAnti-oxidation

CBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function

More about Cannabidiol - derived from extract or tincture or resin of cannabis
Bisabolol~0.15–0.55%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Lecithin~0.2–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Ceramide np~0.15–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Dipotassium glycyrrhizate~0.1–0.35%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Tocopherol~0.1–0.35%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Caprylhydroxamic acid~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
1,2-hexanediol~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Ingredient list view

Water, Glycerin, Betaine, Coco-caprylate, Triethylhexanoin, Sodium acrylates copolymer, Calendula officinalis flower extract, Cannabis sativa seed oil, Ceteareth-30, Cetearyl alcohol, Glyceryl stearate, Mauritia flexuosa fruit oil, Polyglyceryl-3 methylglucose distearate, Glyceryl caprylate, Cannabidiol - derived from extract or tincture or resin of cannabis, Bisabolol, Lecithin, Ceramide np, Dipotassium glycyrrhizate, Tocopherol, Caprylhydroxamic acid, 1,2-hexanediol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDHypoallergenic CBD Nourishing & Calming MoisturizerYOUR PRODUCTDerma ESkin De-Stress Calming CBD MoisturizerPaula's choiceCBD Skin Transformative Treatment Milk Full SizeEcooking50+ Wake Up Cream
Match—71%69%69%
Price$58.50$16.45−$42.05$33.60−$24.90$35.10−$23.40
Shared key ingredients—3 of 83 of 82 of 8
Key difference—PanthenolPanthenolNiacinamide
Irritancy Medium Low Medium Low
Drying alcohol————
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Product summary

Based on the ingredient list, "Perricone MD - Hypoallergenic CBD Nourishing & Calming Moisturizer" can work well for skin moisturization. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Perricone MD - Hypoallergenic CBD Nourishing & Calming Moisturizer ticks this box. Humectants in this product (betaine and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, cannabis sativa seed oil, cetearyl alcohol, coco-caprylate and glyceryl caprylate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • What makes this product special is the inclusion of Cannabidiol, or CBD (0.20% - 0.80%). CBD is a new active in skincare, and the research about it is still ongoing. It is already clear though that CBD can bind to skin cell receptors. It can help reduce inflammation, itching, and help support skin barrier function. It also has a promise in reducing acne.
  • As a plus, this moisturizer also contains Ceramides (ceramide np 0.15% - 0.55%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, lecithin and dipotassium glycyrrhizate

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails from 59.00$ up to 99.00$ in the United States and from 30.50£ up to 1689.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

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Perricone MD Hypoallergenic CBD Nourishing & Calming Moisturizer
Perricone MDHypoallergenic CBD Nourishing & Calming Moisturizer

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