Perricone MD Essential Fx Acyl-Glutathione: Eyelid Lift Serum
Works for
MoisturizingPalmitoyl tripeptide-38, Pantethine + 9 moreWorks well
“It quickly works to replenish skin’s natural moisture barrier, creating a more even-textured surface for smoother, longer-lasting eye makeup application.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, pantethine.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tripeptide-38
Anti-agingPalmitoyl tripeptide-38, Tetrahexyldecyl ascorbateMay help
“Ultra-lightweight serum with a fluid, fast-absorbing texture visibly smooths eyelid creases, crepiness and uneven texture, as it noticeably improves the look of sagging lids and diminishes the appearance of under-eye circles and darkness.”
This product contains palmitoyl tripeptide-38. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Anti-oxidationTetrahexyldecyl ascorbate ~2.5–3%Under-dosed
Effective ingredients missing or their concentration is too low.
Evens skin toneTetrahexyldecyl ascorbate ~2.5–3%Under-dosed
“Addresses loss of elasticity and discoloration.”
Effective ingredients missing or their concentration is too low
Can it cause trouble?
Irritancy1 strong irritant: Rosmarinus officinalis leaf extractMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Propanediol~5.9–7.2%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolPantethine~4.7–5.7%
- Irritation risk
- Low
Helps to hydrate the skin by improving its barrier funciton
More about PantethineGlycerin~3.2–4%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinTetrahexyldecyl ascorbate~2.5–3%
- Irritation risk
- Medium
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
More about Tetrahexyldecyl ascorbateS-palmitoylglutathione~2–2.5%
- Irritation risk
- Low
Dimethyl mea~1.8–2.2%
- Irritation risk
- Low
Palmitoyl tripeptide-38~1.6–1.9%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-38Acetyl tyrosine~1.3–1.6%
- Irritation risk
- Low
Avena sativa kernel extract~1.1–1.3%
- Irritation risk
- Low
An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties
More about Avena sativa kernel extractXanthan gum~0.8–1.15%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumMacadamia ternifolia seed oil~0.7–1.05%
- Irritation risk
- Medium
Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients
More about Macadamia ternifolia seed oilLinum usitatissimum seed oil~0.6–0.85%
Salvia hispanica seed oil~0.6–0.9%
- Irritation risk
- Low
Chia seed oil. Helps to soften the upper layer of the skin and might be helpful in repairing skin barrier
More about Salvia hispanica seed oilSilica cetyl silylate~0.55–0.8%
- Irritation risk
- Low
Ethylhexylglycerin~0.5–0.8%
Sodium hyaluronate~0.5–0.75%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateHelianthus annuus seed oil~0.45–0.65%
- Irritation risk
- Low
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
More about Helianthus annuus seed oilRosmarinus officinalis leaf extract~0.3–0.55%
- Irritation risk
- High
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
More about Rosmarinus officinalis leaf extractTetrasodium glutamate diacetate~0.3–0.55%
- Irritation risk
- Low
Helps stabilize the product formulation
More about Tetrasodium glutamate diacetateAcrylates/c10-30 alkyl acrylate crosspolymer~0.25–0.5%
- Irritation risk
- Medium
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
More about Acrylates/c10-30 alkyl acrylate crosspolymerCaprylyl glycol~0.25–0.5%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolHydroxypropyl cyclodextrin~0.25–0.45%
- Irritation risk
- Medium
Used to stabilize product formulations and help soften the upper layer of the skin
More about Hydroxypropyl cyclodextrinPhenoxyethanol~0.2–0.35%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolSilica~0.25–0.45%
Titanium dioxide~0.15–0.3%
- Irritation risk
- Low
Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin
More about Titanium dioxideIron oxides~0.1–0.2%
- Irritation risk
- Low
An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear
More about Iron oxidesIngredient list view
Water, Propanediol, Pantethine, Glycerin, Tetrahexyldecyl ascorbate, S-palmitoylglutathione, Dimethyl mea, Palmitoyl tripeptide-38, Acetyl tyrosine, Avena sativa kernel extract, Xanthan gum, Macadamia ternifolia seed oil, Linum usitatissimum seed oil, Salvia hispanica seed oil, Silica cetyl silylate, Ethylhexylglycerin, Sodium hyaluronate, Helianthus annuus seed oil, Rosmarinus officinalis leaf extract, Tetrasodium glutamate diacetate, Acrylates/c10-30 alkyl acrylate crosspolymer, Caprylyl glycol, Hydroxypropyl cyclodextrin, Phenoxyethanol, Silica, Titanium dioxide, Iron oxides
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDEssential Fx Acyl-Glutathione: Eyelid Lift SerumYOUR PRODUCT | Sanctuary SpaPower Peptide Awakening Eye Serum | NIODFractionated Eye-Contour Concentrate Serum | Derm InstituteYouth Alchemy Eye Serum | |
|---|---|---|---|---|
| Match | — | 42% | 41% | 40% |
| Price | — | $0.40 | $44.58 | $290.00 |
| Shared key ingredients | — | 2 of 10 | 3 of 10 | 4 of 10 |
| Key difference | — | Caffeine | Decapeptide-22 | Retinol |
| Irritancy | Medium | Low | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Proactiv Eye Brightening SerumThe Ordinary Multi-Peptide Eye Serum
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.
- 1Topical use of dexpanthenol in skin disordersncbi.nlm.nih.gov
- 2
- 3
- 4
- 5
- 6Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
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