Cold Plasma Plus+ The Intensive Hydrating Complex Duo
Efficacy 100/100·Medium irritancy
Efficacy measures how well the formula delivers the claims the brand advertises · 3 of 3 advertised claims delivered
"Perricone MD - Cold Plasma Plus+ The Intensive Hydrating Complex Duo" is effective for: Moisturizing, Evens skin tone, Exfoliation and Anti-agingIngredient calloutsThis moisturizer also contains Peptides (palmitoyl tetrapeptide-7 0.25% …
Product summary
"Perricone MD - Cold Plasma Plus+ The Intensive Hydrating Complex Duo" is effective for: Moisturizing, Evens skin tone, Exfoliation and Anti-aging
Ingredient callouts
- This moisturizer also contains Peptides (palmitoyl tetrapeptide-7 0.25% - 0.50%, palmitoyl tripeptide-1 0.25% - 0.50%, acetyl tetrapeptide-9 0.25% - 0.45%, acetyl tetrapeptide-11 0.25% - 0.45%, acetyl hexapeptide-8 0.25% - 0.45% and copper tripeptide-1 0.30% - 0.55%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails for 358.00$ in the United States.
For a detailed price comparison: click here.
Product claims breakdown
Moisturizing17 ingredients contribute at the levels belowStrong evidence
17 ingredients contribute at the levels below
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, acetyl tetrapeptide-11, acetyl tetrapeptide-9, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
ACETYL TETRAPEPTIDE-9Role: HeroA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
ACETYL TETRAPEPTIDE-11Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
COPPER TRIPEPTIDE-1Role: Key activeA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%
ACETYL HEXAPEPTIDE-8Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
PALMITOYL TRIPEPTIDE-1Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
PETROLATUMRole: Under-dosedOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.25–0.5%
PALMITOYL TETRAPEPTIDE-7Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
POLYSILICONE-11Role: Key activeA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.25–0.5%
SODIUM HYALURONATERole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.6%
CAPRYLIC/CAPRIC TRIGLYCERIDERole: Key activeA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.6–5.6%
DIMETHICONERole: Key activeA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–0.85%
ECHIUM PLANTAGINEUM SEED OILRole: Key activeA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin~0.2–0.4%
GLYCERINRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.2%
HELIANTHUS ANNUUS SEED OILRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%
PHYTOSTEROLSRole: Key activeLipids that work as an emollient and can be helpful in repairing skin barrier function~0.15–0.25%
Evens skin toneGLYCOLIC ACID at ~0.2–0.35%Strong evidence
GLYCOLIC ACID at ~0.2–0.35%
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
GLYCOLIC ACIDRole: Key activeAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.2–0.35%
C12-15 alkyl benzoateRole: Key activeEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~4.8–5.9%
Caprylic/capric triglycerideRole: Key activeA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.6–5.6%
GlycerinRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.2%
Cetearyl alcoholRole: Key activeA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.8%
DimethiconeRole: Key activeA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–0.85%
Hydrogenated vegetable oilRole: Key activeAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.45–0.7%
Sodium hyaluronateRole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.6%
Copper tripeptide-1Role: Key activeA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%
Acetyl hexapeptide-8Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-11Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-9Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-1Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Palmitoyl tetrapeptide-7Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Rosmarinus officinalis leaf extractRole: Key activeCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.4%
Polysilicone-11Role: Key activeA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.25–0.5%
Echium plantagineum seed oilRole: Key activeA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin~0.2–0.4%
Helianthus annuus seed oilRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%
PhytosterolsRole: Key activeLipids that work as an emollient and can be helpful in repairing skin barrier function~0.15–0.25%
Anti-agingGLYCOLIC ACID at ~0.2–0.35% + 6 more curated activesStrong evidence
GLYCOLIC ACID at ~0.2–0.35% + 6 more curated actives
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, acetyl tetrapeptide-11, acetyl tetrapeptide-9, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
ACETYL TETRAPEPTIDE-9Role: HeroA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
ACETYL TETRAPEPTIDE-11Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
COPPER TRIPEPTIDE-1Role: Key activeA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%
GLYCOLIC ACIDRole: Key activeAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.2–0.35%
ACETYL HEXAPEPTIDE-8Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
PALMITOYL TRIPEPTIDE-1Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
PALMITOYL TETRAPEPTIDE-7Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
ExfoliationGLYCOLIC ACID at ~0.2–0.35% delivers this without it being on the labelQuiet bonus
GLYCOLIC ACID at ~0.2–0.35% delivers this without it being on the label
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.
GLYCOLIC ACIDRole: Key activeAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.2–0.35%
C12-15 alkyl benzoateRole: Key activeEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~4.8–5.9%
Caprylic/capric triglycerideRole: Key activeA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.6–5.6%
GlycerinRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.2%
Cetearyl alcoholRole: Key activeA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.8%
DimethiconeRole: Key activeA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–0.85%
Hydrogenated vegetable oilRole: Key activeAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.45–0.7%
Sodium hyaluronateRole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.6%
Copper tripeptide-1Role: Key activeA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%
Acetyl hexapeptide-8Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-11Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-9Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-1Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Palmitoyl tetrapeptide-7Role: Key activeA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Rosmarinus officinalis leaf extractRole: Key activeCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.4%
Polysilicone-11Role: Key activeA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.25–0.5%
Echium plantagineum seed oilRole: Key activeA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin~0.2–0.4%
Helianthus annuus seed oilRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%
PhytosterolsRole: Key activeLipids that work as an emollient and can be helpful in repairing skin barrier function~0.15–0.25%
Irritancy14 flagged ingredients — patch-test recommendedHigh risk
14 flagged ingredients — patch-test recommended
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.2–0.4%est.
Coco-glucosideUsed as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritatingHigh~0.3–0.55%est.
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.2–0.35%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinLow~4.6–5.6%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Low~0.25–0.45%est.
Echium plantagineum seed oilA plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skinLow~0.2–0.4%est.
PhytosterolsLipids that work as an emollient and can be helpful in repairing skin barrier functionLow~0.15–0.25%est.
ComedogenicCetearyl alcohol ~1.5–1.8% — rinse-off or low %Low risk
Cetearyl alcohol ~1.5–1.8% — rinse-off or low %
We flag 3 ingredients with a low-to-moderate comedogenic rating — at these concentrations, or in rinse-off use, they're unlikely to clog pores for most skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product textureMed~1.5–1.8%est.
Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skinMed~0.45–0.7%est.
~ marks concentrations estimated from label position and typical use levels
Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
C12-15 alkyl benzoate~4.8–5.9%
Caprylic/capric triglyceride~4.6–5.6%
Dicaprylyl carbonate~3.3–4%
Propanediol~2.4–3%
Shea butter ethyl esters~2–2.5%
Glycerin~1.8–2.2%
Cetearyl alcohol~1.5–1.8%
Behenyl alcohol~1.3–1.6%
Bentonite~1–1.2%
Glyceryl stearate~0.7–1.1%
Hydrogenated vegetable glycerides citrate~0.6–0.9%
Dimethicone~0.55–0.85%
Isoamyl laurate~0.5–0.7%
Hydrogenated vegetable oil~0.45–0.7%
Hydrogenated soybean oil~0.45–0.65%
Butylene glycol~0.4–0.6%
Sodium hyaluronate~0.3–0.6%
Copper tripeptide-1~0.3–0.55%
Phosphatidylcholine~0.3–0.55%
Acetyl hexapeptide-8~0.25–0.45%
Acetyl tetrapeptide-11~0.25–0.45%
Acetyl tetrapeptide-9~0.25–0.45%
Palmitoyl tripeptide-1~0.25–0.5%
Palmitoyl tetrapeptide-7~0.25–0.5%
Dimethyl mea~0.25–0.45%
Tetrahexyldecyl ascorbate~0.25–0.45%
Tyrosine~0.25–0.4%
Hydrolyzed myrtus communis leaf extract~0.25–0.45%
Rosmarinus officinalis leaf extract~0.2–0.4%
Polysorbate 20~0.25–0.5%
Dimethyl isosorbide~0.25–0.45%
Polysilicone-11~0.25–0.5%
Phenoxyethanol~0.25–0.45%
Petrolatum~0.25–0.5%
Hydrogenated olive oil~0.2–0.4%
Caprylyl glycol~0.25–0.45%
Coco-glucoside~0.3–0.55%
Hydrogenated jojoba oil~0.3–0.5%
Echium plantagineum seed oil~0.2–0.4%
Citric acid~0.2–0.35%
Glycolic acid~0.2–0.35%
Helianthus annuus seed oil~0.2–0.35%
Glycine soja lipids~0.15–0.3%
Carbomer~0.15–0.3%
Disodium edta~0.15–0.25%
Phytosterols~0.15–0.25%
Ethylhexylglycerin~0.1–0.15%
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