Works for
Anti-agingSerine, TocopherolMay help
“Expect youthful and healthy-looking results.”
This product contains serine. There is some human evidence that this ingredient helps reduce and prevent fine lines and wrinkles and improve skin elasticity and firmness, though it is smaller or less consistent than the evidence for the best anti-aging ingredients.
MoisturizingGlycerin, Leontopodium alpinum callus culture extract + 16 moreWorks
“A dual-approach sealant that hydrates and retains moisture, with a lightweight profile.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, anhydroxylitol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.
Evens skin toneAlanineNot delivered
This product contains ingredients (alanine) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.
Anti-oxidationLeontopodium alpinum callus culture extract, Mangifera indica seed butter + 2 moreNot delivered
This product contains antioxidants (leontopodium alpinum callus culture extract). In theory, they could help neutralize free radicals in skin and lessen the damage it gets from the UV light (sun), but there is no evidence that these ingredients can have a noticeable effect in skin.
Can it cause trouble?
Irritancy7 flagged ingredientsMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Caprylyl methicone~22–34%
- Irritation risk
- Low
A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin
More about Caprylyl methiconeWater~11–16%
Peg-12 dimethicone/ppg-20 crosspolymer~3.6–5.4%
- Irritation risk
- Low
Helps water and oil mix together
More about Peg-12 dimethicone/ppg-20 crosspolymerGlycerin~3.2–4.8%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPropanediol~2.4–3.7%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolSodium polyacrylate~1.9–2.8%
- Irritation risk
- Low
Used to create a gel-like product texture, as well as to stabilize emulsions
More about Sodium polyacrylateLeontopodium alpinum callus culture extract~1.5–2.2%
- Irritation risk
- Low
A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin
More about Leontopodium alpinum callus culture extractDisodium acetyl glucosamine phosphate~1.3–1.9%
- Irritation risk
- Low
Proline~1.1–1.7%
Alanine~0.9–1.35%
- Irritation risk
- Low
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
More about AlanineSerine~0.55–1.3%
- Irritation risk
- Low
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
More about SerineGlucose~0.45–1.1%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
More about GlucoseXylitol~0.4–1%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and repair the skin barrier function
More about XylitolXylitylglucoside~0.4–0.95%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and repair the skin barrier function
More about XylitylglucosideAnhydroxylitol~0.4–0.9%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and repair the skin barrir function
More about AnhydroxylitolAdansonia digitata fruit extract~0.4–0.95%
- Irritation risk
- Low
Polypodium vulgare rhizome extract~0.35–0.85%
- Irritation risk
- Low
Cetraria islandica thallus extract~0.35–0.8%
- Irritation risk
- Low
Sphagnum magellanicum extract~0.3–0.75%
- Irritation risk
- Low
Pseudoalteromonas ferment extract~0.3–0.7%
- Irritation risk
- Low
Tocopherol~0.35–0.85%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolTocopheryl acetate~0.35–0.85%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateMangifera indica seed butter~0.2–0.7%
- Irritation risk
- Low
Helps to soften the upper layer of the skin and might have some anti-oxidant effect
More about Mangifera indica seed butterOrbignya oleifera seed oil~0.3–0.75%
- Irritation risk
- Low
A plant oil that can help soften the upper layer of the skin. Might be helpful in calming down inflammation in skin
More about Orbignya oleifera seed oilSqualane~0.3–0.7%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneLecithin~0.2–0.75%
- Irritation risk
- Low
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
More about LecithinDisiloxane~0.15–0.6%
- Irritation risk
- Low
Trimethylsiloxysilicate~0.15–0.65%
- Irritation risk
- Low
A type of silicone that helps create a nice product consistency and support the delivery of other ingredients
More about TrimethylsiloxysilicateCyclopentasiloxane~0.15–0.7%
- Irritation risk
- Low
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
More about CyclopentasiloxaneDimethicone~0.2–0.7%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconePolysilicone-11~0.2–0.75%
- Irritation risk
- Low
A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel
More about Polysilicone-11Dimethicone/vinyl dimethicone crosspolymer~0.2–0.7%
- Irritation risk
- Low
Used to stabilize product formulations and create a nice product texture
More about Dimethicone/vinyl dimethicone crosspolymerHydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.15–0.7%
- Irritation risk
- Medium
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerXanthan gum~0.15–0.7%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumCaprylyl glycol~0.2–0.7%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolSodium benzoate~0.25–0.5%
Potassium sorbate~0.1–0.5%
Citric acid~0.1–0.35%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidSodium phosphate~0.1–0.3%
Sodium hydroxide~0.1–0.35%
Ethylhexylglycerin~0.05–0.3%
Phenoxyethanol~0.1–0.3%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolChlorphenesin~0.05–0.25%
Ingredient list view
Caprylyl methicone, Water, Peg-12 dimethicone/ppg-20 crosspolymer, Glycerin, Propanediol, Sodium polyacrylate, Leontopodium alpinum callus culture extract, Disodium acetyl glucosamine phosphate, Proline, Alanine, Serine, Glucose, Xylitol, Xylitylglucoside, Anhydroxylitol, Adansonia digitata fruit extract, Polypodium vulgare rhizome extract, Cetraria islandica thallus extract, Sphagnum magellanicum extract, Pseudoalteromonas ferment extract, Tocopherol, Tocopheryl acetate, Mangifera indica seed butter, Orbignya oleifera seed oil, Squalane, Lecithin, Disiloxane, Trimethylsiloxysilicate, Cyclopentasiloxane, Dimethicone, Polysilicone-11, Dimethicone/vinyl dimethicone crosspolymer, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Xanthan gum, Caprylyl glycol, Sodium benzoate, Potassium sorbate, Citric acid, Sodium phosphate, Sodium hydroxide, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Compare prices
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| NIODHydration Vaccine MoisturiserYOUR PRODUCT | CetaphilRestoring Water Gel | BlissYouth Got This Moisturizer | Step 4: MoisturizeSepicalm 03% Moisturizer | |
|---|---|---|---|---|
| Match | — | 56% | 54% | 54% |
| Price | $56.00 | $17.99−$38.01 | $27.78−$28.22 | — |
| Shared key ingredients | — | 5 of 13 | 7 of 13 | 5 of 13 |
| Key difference | — | Niacinamide | Retinol | Oatmeal Extract |
| Irritancy | Medium | Low | Medium | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Be Minimalist Sepicalm 03% MoisturizerBoots No7 HydraLuminous+ Night Gel
Product summary
"NIOD - Hydration Vaccine Moisturiser" could be helpful for: Anti-aging and Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Humectants (xylitylglucoside 0.45% - 1.00%, glycerin 3.20% - 4.80%, anhydroxylitol 0.40% - 0.95% and alanine 0.90% - 1.35%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails from 35.90£ up to 55.00£ in the United Kingdom, from 66.03$ up to 85.00$ in the United States, for 105.90A$ in Australia and for 113.00CA$ in Canada.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 13 studies and safety reviews.
- 1
- 2
- 3
- 4Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
- 5
- 6Vitamin E in dermatologyncbi.nlm.nih.gov
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