Neutrogena Hydro Boost Hand Gel Cream

Neutrogena Hydro Boost Hand Gel Cream

Efficacy75/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Moisturizing
8 ingredients credited for this claim
Good support
What the product description says
“Hydro Boost Hand Gel Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetyl alcohol.

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.3–0.55%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.6%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.3–0.55%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.3–0.55%
PetrolatumUnder-dosedEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.25–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.25%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 5 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.35–0.65%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~4.1–5%est.
EthylhexylglycerinA preservativeMedium~1.6–2%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~1.2–1.5%est.
Ci 42090A colorant (dye)Medium~0.35–0.65%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~4.1–5%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.3–0.55%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.6–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Isopropyl palmitate~4.1–5%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Cetyl alcohol~2.5–3%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Dimethicone~2.4–2.9%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium hyaluronate~1.9–2.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Ethylhexylglycerin~1.6–2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Petrolatum~1.5–1.8%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Caprylyl glycol~1.2–1.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Cetearyl olivate~0.95–1.15%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Sorbitan olivate~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Carbomer~0.55–0.85%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium polyacrylate~0.55–0.85%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Sodium hydroxide~0.45–0.7%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Tocopherol~0.45–0.65%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Phenoxyethanol~0.45–0.65%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Parfum~0.35–0.65%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ci 42090~0.35–0.65%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Water~0.3–0.55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Isopropyl palmitate~0.3–0.55%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Cetyl alcohol~0.3–0.55%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Dimethicone~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Ethylhexylglycerin~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Petrolatum~0.25–0.5%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Cetearyl olivate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Sorbitan olivate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Carbomer~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium polyacrylate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Sodium hydroxide~0.15–0.3%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Tocopherol~0.15–0.25%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Phenoxyethanol~0.1–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Parfum~0.05–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ci 42090~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Ingredient list view

Water, Glycerin, Isopropyl palmitate, Cetyl alcohol, Dimethicone, Sodium hyaluronate, Ethylhexylglycerin, Petrolatum, Caprylyl glycol, Cetearyl olivate, Sorbitan olivate, Carbomer, Sodium polyacrylate, Sodium hydroxide, Tocopherol, Phenoxyethanol, Parfum, Ci 42090, Water, Glycerin, Isopropyl palmitate, Cetyl alcohol, Dimethicone, Sodium hyaluronate, Ethylhexylglycerin, Petrolatum, Caprylyl glycol, Cetearyl olivate, Sorbitan olivate, Carbomer, Sodium polyacrylate, Sodium hydroxide, Tocopherol, Phenoxyethanol, Parfum, Ci 42090

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Neutrogena
$5.62
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Walgreens
$5.99
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Ulta
$7.59
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Amazon USPrice as of 10/15/2026 06:01 GMT
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Amazon USPrice as of 10/15/2026 03:51 GMT
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Walgreens
$11.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NeutrogenaHydro Boost Hand Gel CreamYOUR PRODUCTKoseCoenRich Q10 Brightening Tone Up Hand CreamUp&UpUnscented Daily Moisturizing Hand LotionAveenoSkin Relief Intense Moisture Hand Cream With Oat
Match—58%58%58%
Price$5.45$11.40+$5.95$6.49+$1.04$8.29+$2.84
Shared key ingredients—5 of 63 of 63 of 6
Key difference—Mineral OilAvena Sativa Kernel FlourAvena Sativa Kernel Flour
Irritancy Medium Low Low Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 8 studies and safety reviews.

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Neutrogena Hydro Boost Hand Gel Cream
NeutrogenaHydro Boost Hand Gel Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.