Neulii Derma Ectocica 13 Cream

Neulii Derma Ectocica 13 Cream

Efficacy100/100IrritancyHigh
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Works for

3 of 3 advertised claims delivered

Moisturizing
12 ingredients credited for this claim
Strong support
What the product description says
“Hyaluronic Acid helps retain moisture in skin, while Ectoin protects and nourishes dry skin.”
Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: phenyl trimethicone, glyceryl caprylate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–3%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.15–0.65%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.25%
MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.05–0.2%
Phenyl trimethiconeKey active· OcclusiveEffect: HighA type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture~1.7–2.6%
Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.2%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.15%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~0.35–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.5–5.3%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~5.8–8.8%
Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.45–1.1%
Anti-aging
5 ingredients credited for this claim
Strong support
What the product description says
“Helps reduce wrinkles and brighten up skin tone with its transparent gel texture.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, madecassoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–3%
AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.15%
MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.05–0.2%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.15–0.65%
Evens skin tone
2 ingredients credited for this claim
Strong support
What the product description says
“Helps reduce wrinkles and brighten up skin tone with its transparent gel texture.”
Source: Yesstyle

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–3%
MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.05–0.2%
Anti-oxidation
Not advertised by the brand · 6 ingredients credited for this claim
Strong support

This product contains antioxidants (asiaticoside, madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.05–0.2%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.15%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.6%
Paeonia suffruticosa root extractEffect: Low~0.1–0.35%
Pelargonium graveolens flower oilEffect: LowAn essential oil. Can be irritating. Can become an allergen with oxidation~0.1–0.3%
Rosmarinus officinalis leaf oilEffect: Low, below effective doseA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin~0.1–0.4%
Anti-blemish
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2–3%

Can it cause trouble?

Irritancy
9 strong irritants: Alcohol, Citrus aurantium dulcis oil + 7 more — patch-test recommended
High risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~2.7–4.1%est.
Ethyl hexanediolUsed to dissolve other ingredients. Might be irritatingHigh~1.4–2.1%est.
Citrus aurantium dulcis oilUsed as a fragrance. It can be irritating and cause photosensitivityHigh~0.15–0.6%est.
Citrus aurantium bergamia fruit oilA plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivityHigh~0.1–0.45%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.1–0.45%est.
Rosmarinus officinalis leaf oilA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skinHigh~0.1–0.4%est.
Citrus nobilis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.1–0.35%est.
Paeonia suffruticosa root extract—High~0.1–0.35%est.
Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.1–0.3%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.01–0.1%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.55–1.3%est.
1,2-hexanediolA preservativeMedium~0.15–0.7%est.
Disodium edtaStabilizes the product formulationMedium~0.15–0.55%est.
EthylhexylglycerinA preservativeMedium~0.1–0.35%est.
MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.05–0.2%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.05–0.15%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.05–0.25%est.
Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.05–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Butylene glycol~5.8–8.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Glycerin~3.5–5.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Alcohol~2.7–4.1%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Niacinamide~2–3%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-blemishAnti-agingReduces irritationReduces rednessAnti-inflammatoryAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Phenyl trimethicone~1.7–2.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture

More about Phenyl trimethicone
Ethyl hexanediol~1.4–2.1%
Irritant · high
Irritation risk
High

Used to dissolve other ingredients. Might be irritating

More about Ethyl hexanediol
Tromethamine~1.2–1.8%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Carbomer~0.95–1.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Polysorbate 60~0.55–1.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Glyceryl caprylate~0.45–1.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Ectoin~0.35–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Xylitol~0.2–0.75%
Formula
Irritation risk
Low

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitol
1,2-hexanediol~0.15–0.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Hyaluronic acid~0.15–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Adenosine~0.15–0.6%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Citrus aurantium dulcis oil~0.15–0.6%
Irritant · high
Irritation risk
High

Used as a fragrance. It can be irritating and cause photosensitivity

More about Citrus aurantium dulcis oil
Disodium edta~0.15–0.55%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Citrus aurantium bergamia fruit oil~0.1–0.45%
Irritant · high
Irritation risk
High

A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity

More about Citrus aurantium bergamia fruit oil
Lavandula angustifolia oil~0.1–0.45%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Rosmarinus officinalis leaf oil~0.1–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAntibacterial

A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin

More about Rosmarinus officinalis leaf oil
Allantoin panthenol~0.1–0.4%
Formula
Citrus nobilis peel oil~0.1–0.35%
Irritant · high
Irritation risk
High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus nobilis peel oil
Ethylhexylglycerin~0.1–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Paeonia suffruticosa root extract~0.1–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation
More about Paeonia suffruticosa root extract
Cynanchum atratum extract~0.05–0.3%
Formula
Pelargonium graveolens flower oil~0.1–0.3%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil
Madecassoside~0.05–0.2%
Hero · MoisturizingIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside
Asiaticoside~0.05–0.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Madecassic acid~0.05–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Asiatic acid~0.05–0.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryMoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Limonene~0.01–0.1%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Ingredient list view

Water, Butylene glycol, Glycerin, Alcohol, Niacinamide, Phenyl trimethicone, Ethyl hexanediol, Tromethamine, Carbomer, Polysorbate 60, Glyceryl caprylate, Ectoin, Xylitol, 1,2-hexanediol, Hyaluronic acid, Adenosine, Citrus aurantium dulcis oil, Disodium edta, Citrus aurantium bergamia fruit oil, Lavandula angustifolia oil, Rosmarinus officinalis leaf oil, Allantoin panthenol, Citrus nobilis peel oil, Ethylhexylglycerin, Paeonia suffruticosa root extract, Cynanchum atratum extract, Pelargonium graveolens flower oil, Madecassoside, Asiaticoside, Madecassic acid, Asiatic acid, Linalool, Limonene

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NeuliiDerma Ectocica 13 CreamYOUR PRODUCTTOSOWOONGJeju Mayu CreamSkinRx LabMadeCera CreamDr.wantMega Zinc Cream
Match—97%97%95%
Price$13.28—$2.64−$10.64$13.88+$0.60
Shared key ingredients—8 of 107 of 108 of 10
Key difference—Oligopeptide-1Ceramide NpPanthenol
Irritancy High Medium Medium Medium
Drying alcohol Contains drying alcohol —— Contains drying alcohol
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Product summary

Based on the ingredients included, "Neulii - Derma Ectocica 13 Cream" works well for moisturizing the skin. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (glycerin, hyaluronic acid and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (phenyl trimethicone and glyceryl caprylate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We love that this moisturizer contains a good concentration of niacinamide 2.00% - 3.00%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
  • Adenosine 0.15% - 0.60%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.05% - 0.20%, madecassic acid 0.05% - 0.25%, asiaticoside 0.05% - 0.15% and asiatic acid 0.05% - 0.20% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 13.28$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 31 studies and safety reviews.

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Neulii Derma Ectocica 13 Cream
NeuliiDerma Ectocica 13 Cream

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