Works for
Evens skin toneNiacinamide, Madecassoside + 1 moreWorks well
“This anti-wrinkle, brightening serum gives a cooling feeling and a non-sticky finish with its transparent gel texture.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
MoisturizingNiacinamide, Madecassoside + 10 moreWorks well
“Hyaluronic Acid helps retain moisture in skin, while Ectoin protects and nourishes dry skin.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": hyaluronic acid, butylene glycol.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide
Anti-agingNiacinamide, Adenosine + 3 moreWorks well
“This anti-wrinkle, brightening serum gives a cooling feeling and a non-sticky finish with its transparent gel texture.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, madecassoside.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Anti-blemishSide benefit · Niacinamide, AllantoinWorks well
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Anti-oxidationSide benefit · Madecassoside, Asiaticoside + 4 moreWorks well
This product contains antioxidants (asiaticoside, madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy8 strong irritants: Citrus aurantium dulcis oil, Citrus aurantium bergamia fruit oil + 6 more — patch-test recommendedHigh risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Dipropylene glycol~7.1–8.6%
- Irritation risk
- Low
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
More about Dipropylene glycolButylene glycol~4.3–5.2%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolNiacinamide~3.2–3.9%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideHydroxyacetophenone~2.4–3%
Carbomer~1.9–2.4%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerTromethamine~1.7–2.1%
Peg-40 hydrogenated castor oil~1.4–1.8%
- Irritation risk
- Medium
Helps oil and water mix together
More about Peg-40 hydrogenated castor oilPpg-26-buteth-26~1.2–1.4%
Caprylyl glycol~1–1.2%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycol1,2-hexanediol~0.65–0.95%
Ectoin~0.55–0.85%
- Irritation risk
- Low
Softens the upper layer of the skin and can support skin barrier function
More about EctoinHyaluronic acid~0.5–0.75%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
More about Hyaluronic acidAdenosine~0.45–0.7%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineDisodium edta~0.45–0.65%
Citrus aurantium dulcis oil~0.45–0.65%
- Irritation risk
- High
Used as a fragrance. It can be irritating and cause photosensitivity
More about Citrus aurantium dulcis oilAllantoin~0.35–0.65%
- Irritation risk
- Low
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
More about AllantoinCitrus aurantium bergamia fruit oil~0.3–0.6%
- Irritation risk
- High
A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity
More about Citrus aurantium bergamia fruit oilLavandula angustifolia oil~0.3–0.55%
- Irritation risk
- High
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
More about Lavandula angustifolia oilRosmarinus officinalis leaf oil~0.3–0.5%
- Irritation risk
- High
A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin
More about Rosmarinus officinalis leaf oilEthylhexylglycerin~0.25–0.5%
Citrus nobilis peel oil~0.25–0.45%
- Irritation risk
- High
A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin
More about Citrus nobilis peel oilPaeonia suffruticosa root extract~0.25–0.4%
Cynanchum atratum extract~0.2–0.35%
- Irritation risk
- Low
Pelargonium graveolens flower oil~0.25–0.4%
- Irritation risk
- High
An essential oil. Can be irritating. Can become an allergen with oxidation
More about Pelargonium graveolens flower oilDipotassium glycyrrhizate~0.2–0.4%
- Irritation risk
- Low
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
More about Dipotassium glycyrrhizateMadecassoside~0.2–0.35%
- Irritation risk
- Medium
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
More about MadecassosideAsiaticoside~0.15–0.25%
- Irritation risk
- Medium
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
More about AsiaticosideMadecassic acid~0.15–0.25%
- Irritation risk
- Medium
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
More about Madecassic acidAsiatic acid~0.1–0.2%
- Irritation risk
- Medium
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
More about Asiatic acidLinalool~0.1–0.15%
Limonene~0.05–0.1%
- Irritation risk
- High
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
More about LimoneneIngredient list view
Water, Dipropylene glycol, Butylene glycol, Niacinamide, Hydroxyacetophenone, Carbomer, Tromethamine, Peg-40 hydrogenated castor oil, Ppg-26-buteth-26, Caprylyl glycol, 1,2-hexanediol, Ectoin, Hyaluronic acid, Adenosine, Disodium edta, Citrus aurantium dulcis oil, Allantoin, Citrus aurantium bergamia fruit oil, Lavandula angustifolia oil, Rosmarinus officinalis leaf oil, Ethylhexylglycerin, Citrus nobilis peel oil, Paeonia suffruticosa root extract, Cynanchum atratum extract, Pelargonium graveolens flower oil, Dipotassium glycyrrhizate, Madecassoside, Asiaticoside, Madecassic acid, Asiatic acid, Linalool, Limonene
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| NeuliiDerma Ectocica 12 SerumYOUR PRODUCT | VT CosmeticsHydrop Reedle Shot 100hL | ilsoHA-Shot Booster Serum 30ml | Dr. Jart+Cicapair Tiger Grass Repair Serum | |
|---|---|---|---|---|
| Match | — | 94% | 92% | 90% |
| Price | $20.99 | $18.00−$2.99 | $16.12−$4.87 | $53.50+$32.51 |
| Shared key ingredients | — | 8 of 10 | 9 of 10 | 6 of 10 |
| Key difference | — | Panthenol | Anhydroxylitol | Panthenol |
| Irritancy | High | Medium | Medium | High |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Centellian24 Expert Madeca Mela Capture AmpouleMEDI-PEEL Phyto Cica-Nol B5 3000 Shot Serum 50ml
Product summary
"Neulii - Derma Ectocica 12 Serum" is effective for: Anti-blemish, Evens skin tone, Moisturizing and Anti-aging
Ingredient callouts
- A good concentration of Niacinamide (3.20% - 3.90%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Adenosine 0.45% - 0.70%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.10% - 0.20%, madecassic acid 0.15% - 0.25%, asiaticoside 0.15% - 0.25% and madecassoside 0.20% - 0.35% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
- Humectants (hyaluronic acid 0.50% - 0.75%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 13.60$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 34 studies and safety reviews.
- 1
- 2
- 3Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
- 4
- 5
- 6
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