Works for:
based on ingredients and %- Exfoliation
- Anti-aging
- Evens skin tone
- Moisturizing
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"NEOSTRATA - Tri-Therapy Lifting Serum" is effective for: Exfoliation, Anti-aging and Evens skin tone
This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Exfoliating acids (). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run. PHAs (gluconolactone 3.60% - 5.40%) in this product also work for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
- Humectants (glycerin 1.80% - 2.70% and biosaccharide gum-1 0.35% - 0.85%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 100.00$ in the United States, from 51.99CA$ up to 120.00CA$ in Canada, for 56.64A$ in Australia and for 58.81£ in the United Kingdom.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
This silky oil-free serum absorbs beautifully into skin and visibly volumizes to smooth out the appearance of wrinkles and fine lines.
Source: Neostrata
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl tyrosinamide, gluconolactone.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
An amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available
Evens skin tone
What does the product description say?
Looking for a multi-tasking serum that addresses concerns like uneven skin tone, rough texture, fine lines and slack skin?
Source: Neostrata
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Exfoliation
What does the product description say?
Ideal for those looking to visibly volumize, exfoliate and renew the surface texture of the skin both day and night.
Source: Neostrata
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Anti-oxidation
This product contains antioxidants (acetyl tyrosinamide, gluconolactone) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
An amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Moisturizing
What does the product description say?
Due to its unique small size, LMW (Low Molecular Weight) Hyaluronic Acid penetrates skin’s surface to attract moisture, providing hydration to visibly improve skin’s texture.
Source: Neostrata
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
biosaccharide gum-1, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethiconol, isopropyl myristate.
A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Attracts water into the upper layer of the skin
An emollient that helps soften the skin. Could be comedogenic
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
An amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available
Helps soften the upper layer of the skin and create a nice product texture
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Used to create a nice product consistency
Used to preserve products, dissolve other ingredients and create a nice product texture
Helps preserve products and creates a nice product texture
A silicone that serves as an emollient. Helps create a nice non-greasy feels
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Exfoliation | |
| Evens skin tone | |
| Moisturizing |
Total Promises Fulfilled score: 93/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 NEOSTRATA Tri-Therapy Lifting Serum | Current | $-1.00 | |
Exuviance Professional Total Correct Serum | 46% | $44.25 | |
Kiehl's Hydro-Plumping Hydrating Serum | 42% | $52.70 | |
 Selfless by Hyram Mandelic Acid & Rice Bran Gentle Exfoliating Serum | 41% | $6.99 | |
 Skingredients Skin Veg Hydrating Hyaluronic Acid Serum | 40% | $49.00 | |
 Naturium PHA Topical Acid 12% | 40% | $15.00 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Peg-8, Gluconolactone, 1,2-hexanediol, Cyclopentasiloxane, Glycerin, Pentylene glycol, Peg-12 dimethicone, Polymethylsilsesquioxane, Acetyl tyrosinamide, Cyclohexasiloxane, Hydrolyzed sodium hyaluronate, Dimethiconol, Biosaccharide gum-1, Polyacrylate-13, Polyisobutene, Isopropyl myristate, Polysorbate 20, Sodium sulfite, Bht, Ammonium hydroxide, Caprylyl glycol, Xanthan gum, Methyldihydrojasmonate, 2,6-dimethyl-7-octen-2-ol, Ethyl acetoacetate, Methyl benzodioxepinone, Phenoxyethanol, Chlorphenesin, Ci 17200, Ci 42090
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Glycerol and the skin: holistic approach to its origin and functions
- A high-strength AHA/bionic acid skincare regimen in combination with a daily AHA home peel containing N-acetyl tyrosinamide (Aminofil) significantly improves signs of aging on the face
- A Novel, Volumizing Cosmetic Formulation Significantly Improves the Appearance of Target Glabellar Lines, Nasolabial Folds, and Crow's Feet in a Double-Blind, Vehicle-Controlled Clinical Trial
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics