NEOSTRATA Skin Active Tri-Therapy Lifting Serum

NEOSTRATA Skin Active Tri-Therapy Lifting Serum

Efficacy93/100IrritancyLow

Works for

Exfoliation
Gluconolactone
Works well
What the product description says
“Renews Tone with Gluconolactone A Polyhydroxy Acid & antioxidant chelator that helps to gently exfoliate and promote a more even skin tone.”
Source: Skinstore

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~3.6–5.4%
Anti-aging
Gluconolactone, Acetyl tyrosinamide
Works well
What the product description says
“Volumizes the look of slack skin with AMINOFIL® Amino acid derivative concentrated to target skin’s hydrating matrix for a more lifted appearance.”
Source: Skinstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl tyrosinamide, gluconolactone.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~3.6–5.4%
Acetyl tyrosinamideKey activeEffect: HighAn amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available~0.6–1.4%
Evens skin tone
Gluconolactone
Works well
What the product description says
“Renews Tone with Gluconolactone A Polyhydroxy Acid & antioxidant chelator that helps to gently exfoliate and promote a more even skin tone.”
Source: Skinstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~3.6–5.4%
Moisturizing
Gluconolactone, Cyclopentasiloxane + 12 more
Works
What the product description says
“Volumizes the look of slack skin with AMINOFIL® Amino acid derivative concentrated to target skin’s hydrating matrix for a more lifted appearance.”
Source: Skinstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: biosaccharide gum-1, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethiconol, isopropyl myristate.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~3.6–5.4%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~2.1–3.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.7%
Peg-12 dimethiconeKey activeEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~1.3–1.9%
PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1.1–1.6%
Acetyl tyrosinamideKey activeEffect: HighAn amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available~0.6–1.4%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.4–0.95%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.4–1%
Biosaccharide gum-1Key active· HumectantEffect: HighHelps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin~0.35–0.85%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~0.35–0.8%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~4.8–7.2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.5–2.2%
Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~0.5–1.2%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.6%
Anti-oxidation
Side benefit · Gluconolactone, Acetyl tyrosinamide
May help

This product contains antioxidants (acetyl tyrosinamide, gluconolactone) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.

GluconolactoneKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~3.6–5.4%
Acetyl tyrosinamideKey activeEffect: MediumAn amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available~0.6–1.4%

Can it cause trouble?

Irritancy
12 flagged ingredients
Low risk
We flag 12 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
MethyldihydrojasmonateUsed as a fragrance. Smells similar to jasmineHigh~0.1–0.4%est.
Peg-8Used to create a nice product consistencyMedium~4.8–7.2%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~3.6–5.4%est.
1,2-hexanediolA preservativeMedium~2–3%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.5–2.2%est.
Sodium sulfiteHelps stabilize and preserve a product formulationMedium~0.1–0.2%est.
BhtA preservativeMedium~0.15–0.65%est.
Ammonium hydroxideHelps adjust the product pHMedium~0.15–0.6%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.6%est.
ChlorphenesinA preservativeMedium~0.05–0.2%est.
Ci 17200A red colorantMedium~0.05–0.15%est.
Ci 42090A colorant (dye)Medium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~0.35–0.8%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Peg-8~4.8–7.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Gluconolactone~3.6–5.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
ExfoliationMoisturizingAnti-agingEvens skin toneAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
1,2-hexanediol~2–3%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Cyclopentasiloxane~2.1–3.1%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Glycerin~1.8–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Pentylene glycol~1.5–2.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Peg-12 dimethicone~1.3–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Peg-12 dimethicone
Polymethylsilsesquioxane~1.1–1.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Acetyl tyrosinamide~0.6–1.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-agingAnti-oxidation

An amino acid derivative. A manufacturer's study shows that it can help somewhat reduce wrinkles when used in combination with a low concentration of glycolic acid. No independent human in-vivo studies of this compound are available

More about Acetyl tyrosinamide
Cyclohexasiloxane~0.5–1.2%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Hydrolyzed sodium hyaluronate~0.4–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Dimethiconol~0.4–1%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Biosaccharide gum-1~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin

More about Biosaccharide gum-1
Polyacrylate-13~0.4–0.9%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13
Polyisobutene~0.35–0.85%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Isopropyl myristate~0.35–0.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Polysorbate 20~0.3–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sodium sulfite~0.1–0.2%
Irritant · medium
Irritation risk
Medium

Helps stabilize and preserve a product formulation

More about Sodium sulfite
Bht~0.15–0.65%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Ammonium hydroxide~0.15–0.6%
Irritant · medium
Irritation risk
Medium

Helps adjust the product pH

More about Ammonium hydroxide
Caprylyl glycol~0.15–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Xanthan gum~0.1–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Methyldihydrojasmonate~0.1–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance. Smells similar to jasmine

More about Methyldihydrojasmonate
2,6-dimethyl-7-octen-2-ol~0.1–0.3%
Formula
Ethyl acetoacetate~0.05–0.25%
Formula
Methyl benzodioxepinone~0.05–0.2%
Formula
Phenoxyethanol~0.05–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Chlorphenesin~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Ci 17200~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Ci 42090~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Ingredient list view

Water, Peg-8, Gluconolactone, 1,2-hexanediol, Cyclopentasiloxane, Glycerin, Pentylene glycol, Peg-12 dimethicone, Polymethylsilsesquioxane, Acetyl tyrosinamide, Cyclohexasiloxane, Hydrolyzed sodium hyaluronate, Dimethiconol, Biosaccharide gum-1, Polyacrylate-13, Polyisobutene, Isopropyl myristate, Polysorbate 20, Sodium sulfite, Bht, Ammonium hydroxide, Caprylyl glycol, Xanthan gum, Methyldihydrojasmonate, 2,6-dimethyl-7-octen-2-ol, Ethyl acetoacetate, Methyl benzodioxepinone, Phenoxyethanol, Chlorphenesin, Ci 17200, Ci 42090

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NEOSTRATASkin Active Tri-Therapy Lifting SerumYOUR PRODUCTExuvianceAge Reverse Total Correct + Sculpt SerumKiehl'sHydro-Plumping Hydrating SerumSelfless by HyramMandelic Acid & Rice Bran Gentle Exfoliating Serum
Match—49%42%41%
Price—$89.00$61.02$15.74
Shared key ingredients—5 of 93 of 93 of 9
Key difference—Ascorbyl GlucosideAdenosineSalicylic Acid
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

"NEOSTRATA - Skin Active Tri-Therapy Lifting Serum" is effective for: Anti-aging, Exfoliation and Evens skin tone

This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Exfoliating acids (). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run. PHAs (gluconolactone 3.60% - 5.40%) in this product also work for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
  • Humectants (glycerin 1.80% - 2.70% and biosaccharide gum-1 0.35% - 0.85%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 75.00£ up to 88.00£ in the United Kingdom, for 100.00$ in the United States and for 120.00CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

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NEOSTRATA Skin Active Tri-Therapy Lifting Serum
NEOSTRATASkin Active Tri-Therapy Lifting Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.