NEOGEN X SUR.MEDIC Dermalogy Real Peptide Serum

NEOGEN X SUR.MEDIC Dermalogy Real Peptide Serum

Efficacy100/100IrritancyMedium

Works for

Moisturizing
Acetyl hexapeptide-8, Tripeptide-1 + 26 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, hexapeptide-11, hexapeptide-9, linoleic acid, niacinamide, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol, tripeptide-1, tripeptide-29

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~26–32%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~5.5–6.7%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function5%
Tripeptide-29HeroEffect: High~4.5–5.5%
Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~3.9–4.7%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~3.6–4.4%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.7–3.3%
Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2–2.4%
Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–1.7%
Nonapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.1–1.3%
Hexapeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1–1.2%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.65–1%
Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.5–0.8%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.75–1.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.7–1.05%
Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.65–0.95%
Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.65–1%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.65–0.95%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.6–0.9%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.55–0.8%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.5–0.75%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.5–0.75%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.45–0.7%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.45–0.7%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.9–1.1%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.7–1.05%
BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.6–0.95%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.75%
Anti-aging
Acetyl hexapeptide-8, Tripeptide-1 + 13 more
Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, copper tripeptide-1, folic acid, hexapeptide-11, hexapeptide-9, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1, tripeptide-29.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~26–32%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~5.5–6.7%
Tripeptide-29Key activeEffect: Medium~4.5–5.5%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~3.9–4.7%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~3.6–4.4%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.7–3.3%
Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2–2.4%
Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–1.7%
Nonapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.1–1.3%
Hexapeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1–1.2%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.65–1%
Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.6–0.95%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.5–0.75%
Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.65–1%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.75%
Evens skin tone
Side benefit · Niacinamide
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.65–1%
Anti-blemish
Side benefit · Niacinamide, Linoleic acid + 2 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: linoleic acid

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.65–1%
Linoleic acidKey activeEffect: MediumAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.5–0.8%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.65–1%
Sodium ascorbyl phosphateUnder-dosedA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.65–1%
Anti-oxidation
Side benefit · Pyridoxine, Coccinia indica fruit extract + 6 more
May help

This product contains antioxidants (pyridoxine) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.

PyridoxineKey activeEffect: MediumMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating~0.6–0.95%
Coccinia indica fruit extractEffect: LowA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin~0.65–0.95%
Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.65–0.95%
Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.65–0.95%
Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.65–0.95%
Solanum melongena fruit extractEffect: LowEggplant fruit extract. Might have some anti-oxidant effect~0.65–0.95%
Sodium ascorbyl phosphateUnder-dosedA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.65–1%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.75%

Can it cause trouble?

Irritancy
1 strong irritant: Ocimum sanctum leaf extract
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.65–1%est.
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.65–0.95%est.
Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.6–0.95%est.
PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.6–0.95%est.
1,2-hexanediolA preservativeMedium~0.9–1.15%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.8–1.2%est.
EthylhexylglycerinA preservativeMedium~0.7–1%est.
Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.65–0.95%est.
Coccinia indica fruit extractA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skinMedium~0.65–0.95%est.
Solanum melongena fruit extractEggplant fruit extract. Might have some anti-oxidant effectMedium~0.65–0.95%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.7–1.05%est.
Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.65–1%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.45–0.7%est.
Thiamine hclCan help attract water to the upper layer of the skin. Is studied as a mosquito repellentMedium~0.3–0.6%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.65–0.95%est.
Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.65–1%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Acetyl hexapeptide-8~26–32%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Copper tripeptide-1~3.9–4.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Tripeptide-1~5.5–6.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Tripeptide-29~4.5–5.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Tripeptide-29
Palmitoyl tetrapeptide-7~3.6–4.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl tripeptide-1~2.7–3.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl pentapeptide-4~2–2.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4
Hexapeptide-12~1.5–1.8%
Formula
Irritation risk
Low
More about Hexapeptide-12
Hexapeptide-9~1.4–1.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9
Tripeptide-2~1.3–1.6%
Formula
Irritation risk
Low
More about Tripeptide-2
Nonapeptide-1~1.1–1.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nonapeptide-1
Hexapeptide-11~1–1.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-11
Water~0.95–1.2%
Formula
Irritation risk
Low

Plain old water

More about Water
Panthenol5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Butylene glycol~0.9–1.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Propanediol~0.9–1.15%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
1,2-hexanediol~0.9–1.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Polyglyceryl-10 laurate~0.8–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Sodium hyaluronate~0.75–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Carbomer~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Ethylhexylglycerin~0.7–1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Tromethamine~0.65–1%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Melia azadirachta leaf extract~0.65–1%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Melia azadirachta flower extract~0.65–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract
Coccinia indica fruit extract~0.65–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin

More about Coccinia indica fruit extract
Solanum melongena fruit extract~0.65–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Eggplant fruit extract. Might have some anti-oxidant effect

More about Solanum melongena fruit extract
Glycerin~0.7–1.05%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ocimum sanctum leaf extract~0.65–0.95%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Xanthan gum~0.65–1%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Curcuma longa root extract~0.6–0.95%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract
Corallina officinalis extract~0.65–0.95%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Caprylyl glycol~0.7–1.05%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Hydrogenated lecithin~0.65–1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Sodium ascorbyl phosphate~0.65–1%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate
Glucose~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Niacinamide~0.65–1%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Chondrus crispus extract~0.65–1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract
Hydroxypropyltrimonium hyaluronate~0.75–1.1%
Formula
Biotin~0.6–0.95%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Pyridoxine~0.6–0.95%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine
Folic acid~0.6–0.95%
Key active
Irritation risk
Low
Works for
Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid
Hydrolyzed hyaluronic acid~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Sodium acetylated hyaluronate~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Cyanocobalamin~0.55–0.8%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Tocopherol~0.5–0.75%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Hyaluronic acid~0.5–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Sodium hyaluronate crosspolymer~0.45–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Hydrolyzed sodium hyaluronate~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Riboflavin~0.4–0.6%
Formula
Irritation risk
Low
More about Riboflavin
Thiamine hcl~0.3–0.6%
Irritant · medium
Irritation risk
Medium

Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent

More about Thiamine hcl
Linoleic acid~0.5–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid
Potassium hyaluronate~0.2–0.4%
Formula
Beta-carotene~0.2–0.35%
Formula
Irritation risk
Low

A colorant adding orange or bright yellow color

More about Beta-carotene
Ingredient list view

Acetyl hexapeptide-8, Copper tripeptide-1, Tripeptide-1, Tripeptide-29, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Palmitoyl pentapeptide-4, Hexapeptide-12, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Hexapeptide-11, Water, Panthenol, Butylene glycol, Propanediol, 1,2-hexanediol, Polyglyceryl-10 laurate, Sodium hyaluronate, Carbomer, Ethylhexylglycerin, Tromethamine, Melia azadirachta leaf extract, Melia azadirachta flower extract, Coccinia indica fruit extract, Solanum melongena fruit extract, Glycerin, Ocimum sanctum leaf extract, Xanthan gum, Curcuma longa root extract, Corallina officinalis extract, Caprylyl glycol, Hydrogenated lecithin, Sodium ascorbyl phosphate, Glucose, Niacinamide, Chondrus crispus extract, Hydroxypropyltrimonium hyaluronate, Biotin, Pyridoxine, Folic acid, Hydrolyzed hyaluronic acid, Sodium acetylated hyaluronate, Cyanocobalamin, Tocopherol, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Riboflavin, Thiamine hcl, Linoleic acid, Potassium hyaluronate, Beta-carotene

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Amazon USPrice as of 11/14 09:07 GMT
$35.72
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$38.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NEOGEN X SUR.MEDICDermalogy Real Peptide SerumYOUR PRODUCTInstaNaturalAnti-Aging Collagen SerumLanoliqueСыворотка для лица питательная гиалуроновая кислота, ниацинамид и витамины NUTRYCos De BAHAP M.A Peptide Serum
Match—63%56%53%
Price$38.00——$7.66−$30.34
Shared key ingredients—3 of 286 of 286 of 28
Key difference—Palmitoyl Tripeptide-5SqualaneAdenosine
Irritancy Medium Low Medium High
Drying alcohol————
View product Shop Shop Shop

More alternatives: Civant Firm RenewMesoestetic Collagen 360 Degree Eye Contour

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Product summary

"Neogen - Dermalogy Real Peptide Serum" is effective for: Moisturizing

This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Peptides (hexapeptide-11 1.00% - 1.20%, nonapeptide-1 1.10% - 1.30%, hexapeptide-9 1.40% - 1.70%, palmitoyl pentapeptide-4 2.00% - 2.40%, palmitoyl tripeptide-1 2.70% - 3.30%, palmitoyl tetrapeptide-7 3.60% - 4.40%, tripeptide-29 4.50% - 5.50%, tripeptide-1 5.50% - 6.70%, copper tripeptide-1 3.90% - 4.70% and acetyl hexapeptide-8 26.00% - 32.00%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • We love that there is also Linoleic Acid in this product (0.50% - 0.80%). Linoleic Acid is one of the skin's natural emollients. It supports the skin barrier and can even help reduce clogged pores.
  • Humectants (panthenol 5.00% (declared), sodium hyaluronate crosspolymer 0.45% - 0.70%, hyaluronic acid 0.50% - 0.75%, sodium acetylated hyaluronate 0.50% - 0.75%, hydrolyzed hyaluronic acid 0.60% - 0.90%, glycerin 0.70% - 1.05%, sodium hyaluronate 0.75% - 1.10%, hexapeptide-9 1.40% - 1.70% and acetyl hexapeptide-8 26.00% - 32.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 38.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 37 studies and safety reviews.

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NEOGEN X SUR.MEDIC Dermalogy Real Peptide Serum
NEOGEN X SUR.MEDICDermalogy Real Peptide Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.