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NCN Pro Skin Care GHK-Cu serum
NCN Pro Skin Care

NCN Pro Skin Care GHK-Cu serum

Efficacy87/100IrritancyLow
See all ingredients

Works for

Moisturizing
Copper tripeptide-1, Chenopodium quinoa seed extract + 7 more
Works well

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": hyaluronic acid, aloe barbadensis extract.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: copper tripeptide-1

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.55–1.3%
Chenopodium quinoa seed extractKey activeEffect: HighHelps soften the upper layer of the skin~1.2–1.8%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.4–0.9%
Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.75%
Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.2–0.75%
Aloe barbadensis extract· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~6.1–9.1%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.8–4.2%
Oryza sativa extractEffect: LowA grain extract that helps to create a thicker product consistency. It might have some anti-oxidant properties and help attract water to the upper layer of the skin~2.2–3.3%
Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.45–1.1%
Anti-aging
Copper tripeptide-1, Centella asiatica extract + 2 more
May help

This product contains centella asiatica extract, copper tripeptide-1. There is some human evidence that these ingredients help reduce and prevent fine lines and wrinkles and improve skin elasticity and firmness, though it is smaller or less consistent than the evidence for the best anti-aging ingredients.

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.55–1.3%
Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.75%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.4–0.9%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.2–0.75%
Anti-oxidation
Side benefit · Centella asiatica extract, Glycyrrhiza glabra root extract + 5 more
May help

This product contains antioxidants (centella asiatica extract) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.75%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~3.8–5.7%
Oryza sativa extractEffect: LowA grain extract that helps to create a thicker product consistency. It might have some anti-oxidant properties and help attract water to the upper layer of the skin~2.2–3.3%
Daucus carota sativa root extractEffect: LowCarrot extract. Might have anti-oxidant properties and be used to add orange color~1.4–2.1%
Panax ginseng root extractEffect: LowA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating~0.95–1.4%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.2–0.75%
Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.45–1.1%

Can it cause trouble?

Irritancy
5 flagged ingredients
Low risk
We flag 5 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Panax ginseng root extractA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritatingHigh~0.95–1.4%est.
Aloe barbadensis extractTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~6.1–9.1%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~3.8–5.7%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.2–0.75%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.1–0.45%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Alternatives
Cheaper, or higher on efficacy
Peptide 500 Ampoule
Mizon Peptide 500 Ampoule
Higher efficacy · 100/10052% match
$23.20
Milk Thistle Repair Serum
BANOBAGI Milk Thistle Repair Serum
Higher efficacy · 100/10050% match
$18.36
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Aloe barbadensis extract~6.1–9.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis extract
Glycyrrhiza glabra root extract~3.8–5.7%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin toneReduces rednessAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Butylene glycol~2.8–4.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Oryza sativa extract~2.2–3.3%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A grain extract that helps to create a thicker product consistency. It might have some anti-oxidant properties and help attract water to the upper layer of the skin

More about Oryza sativa extract
Glycine max seed extract~1.7–2.5%
Formula
Irritation risk
Low
More about Glycine max seed extract
Daucus carota sativa root extract~1.4–2.1%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Carrot extract. Might have anti-oxidant properties and be used to add orange color

More about Daucus carota sativa root extract
Chenopodium quinoa seed extract~1.2–1.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Chenopodium quinoa seed extract
Panax ginseng root extract~0.95–1.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating

More about Panax ginseng root extract
Sea kelp bioferment
Not recognized
Copper tripeptide-1~0.55–1.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Copper tripeptide
Not recognized
Bifida ferment lysate~0.45–1.1%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate
Hyaluronic acid~0.4–0.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Beta-glucan~0.2–0.75%
Key active
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan
Centella asiatica extract~0.2–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-oxidationAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Leuconostoc/radish root ferment filtrate~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Root
Not recognized
Ingredient list view

Water, Aloe barbadensis extract, Glycyrrhiza glabra root extract, Butylene glycol, Oryza sativa extract, Glycine max seed extract, Daucus carota sativa root extract, Chenopodium quinoa seed extract, Panax ginseng root extract, Unknown, Copper tripeptide-1, Unknown, Bifida ferment lysate, Hyaluronic acid, Beta-glucan, Centella asiatica extract, Leuconostoc/radish root ferment filtrate, Unknown

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NCN Pro Skin CareGHK-Cu serumYOUR PRODUCTMizonPeptide 500 AmpouleBANOBAGIMilk Thistle Repair SerumNATUREKINDBoosting Bifida Ampoule
Match—52%50%49%
Price—$23.20$18.36$18.03
Shared key ingredients—3 of 62 of 62 of 6
Key difference—AdenosineNiacinamideNiacinamide
Irritancy Low Low Low Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

  1. 1
    Antioxidant and Anti-Inflammatory Properties of Anthocyanins Extracted from Oryza sativa L. in Primary Dermal Fibroblastshindawi.com
  2. 2
    Rice antioxidants: phenolic acids, flavonoids, anthocyanins, proanthocyanidins, tocopherols, tocotrienols, c-oryzanol, and phytic acidonlinelibrary.wiley.com
  3. 3
    Ginseng in Dermatology: A Reviewncbi.nlm.nih.gov
  4. 4
    Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skinncbi.nlm.nih.gov
  5. 5
    Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
  6. 6
    Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
NCN Pro Skin Care GHK-Cu serum
NCN Pro Skin CareGHK-Cu serum
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