Naturopathica

Naturopathica Argan & Peptide Wrinkle Remedy Eye Cream

Name: Naturopathica - Argan & Peptide Wrinkle Remedy Eye Cream
Brand: Naturopathica

Efficacy87/100IrritancyMedium

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Works for

2 of 2 advertised claims delivered

Moisturizing

Linoleic acid, Palmitoyl tripeptide-38 + 20 more

Strong evidence

What the product description says

“Key Benefits Visibly reduces the appearance of fine lines and wrinkles. Brightens the eye area. Rejuvenates and moisturizes.”

Source: Dermstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, isomalt.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, hippophae rhamnoides oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: linoleic acid, palmitoyl tripeptide-38

Hippophae rhamnoides oilKey active· EmollientEffect: HighA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.~0.5–0.75%

IsomaltKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.6%

LactoperoxidaseKey activeEffect: HighHelps attract water to the upper layer of the skin. In theory, could support healthy skin's microbiome, but evidence of effectiveness in skin is lacking~0.2–0.35%

Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.5–0.75%

Linolenic acidKey active· EmollientEffect: HighAn emollient that helps soften the skin and calm down inflammation~0.45–0.65%

Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~5.7–7%

Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.55–0.8%

Argania spinosa sprout cell extractKey activeEffect: HighPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.55–0.85%

Glucose oxidaseKey activeEffect: HighHelps attract water to the upper layer of the skin~0.15–0.3%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.2%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.3–0.55%

Hydrolyzed rice proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.5–0.75%

C10-18 triglyceridesKey active· EmollientEffect: MediumHelps soften the skin and attract water to its upper layer. Helps create nice product texture~1.8–2.1%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.2–1.4%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.35–0.65%

Porphyridium cruentum extractKey activeEffect: MediumA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect~0.4–0.6%

Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.5–0.75%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.3–1.6%

Cocoglycerides· EmollientEffect: LowHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin~3–3.6%

Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.3–0.5%

Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.7–1.1%

Anti-aging

Palmitoyl tripeptide-38, Glycine soja protein + 2 more

Moderate evidence

What the product description says

“Argan & Peptide Wrinkle Remedy Eye Cream”

From product name

This product contains palmitoyl tripeptide-38. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%

Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.5–0.75%

Argania spinosa sprout cell extractEffect: LowPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.55–0.85%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.7–1.1%

Anti-oxidation

Not advertised by the brand · Superoxide dismutase, Argania spinosa sprout cell extract + 5 more

Strong evidence

This product contains antioxidants (superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Argania spinosa sprout cell extractEffect: LowPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.55–0.85%

Hippophae rhamnoides oilEffect: LowA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.~0.5–0.75%

Hydrolyzed rice proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.5–0.75%

Porphyridium cruentum extractEffect: LowA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect~0.4–0.6%

Can it cause trouble?

Irritancy

1 strong irritant: Bellis perennis flower extract

Medium risk

We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

CocoglyceridesHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skinHigh~3–3.6%est.

Bellis perennis flower extractA plant extract. Used as a fragrance. Can be irritatingHigh~2–2.5%est.

Hippophae rhamnoides oilA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.High~0.5–0.75%est.

PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.3–0.55%est.

Candelilla/jojoba/rice bran polyglyceryl-3 estersHelp oil and water mix togetherMedium~1.5–1.9%est.

Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.8–1.15%est.

Linolenic acidAn emollient that helps soften the skin and calm down inflammationMedium~0.45–0.65%est.

Hydroxypropyl methylcelluloseUsed to create a thicker product consistency and stabilize the formulationMedium~0.25–0.5%est.

Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.3–0.5%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.25%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.7–1.1%est.

Porphyridium cruentum extractA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect3/5~0.4–0.6%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.2–1.4%est.

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Alternatives

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M-61 PowerGlow Eye Cream

CheaperHigher efficacy · 100/10055% match

$82.00

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Squalane~5.7–7%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Glycerin~4.3–5.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Cocoglycerides~3–3.6%

Irritant · high

Irritation risk: High

Works for

CleansingMoisturizing

Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin

More about Cocoglycerides

Glyceryl triacetyl ricinoleate~2.5–3%

Formula

Irritation risk: Low

More about Glyceryl triacetyl ricinoleate

Bellis perennis flower extract~2–2.5%

Irritant · high

Irritation risk: High

A plant extract. Used as a fragrance. Can be irritating

More about Bellis perennis flower extract

C10-18 triglycerides~1.8–2.1%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the skin and attract water to its upper layer. Helps create nice product texture

More about C10-18 triglycerides

Candelilla/jojoba/rice bran polyglyceryl-3 esters~1.5–1.9%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Help oil and water mix together

More about Candelilla/jojoba/rice bran polyglyceryl-3 esters

Glyceryl stearate~1.3–1.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Cetearyl alcohol~1.2–1.4%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Sodium stearoyl lactylate~0.8–1.15%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate

Butyrospermum parkii butter~0.7–1.1%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Palmitoyl tripeptide-38~0.6–0.9%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38

Argania spinosa sprout cell extract~0.55–0.85%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

Plant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals

More about Argania spinosa sprout cell extract

Leontopodium alpinum meristem cell culture~0.55–0.8%

Formula

Irritation risk: Low

More about Leontopodium alpinum meristem cell culture

Superoxide dismutase~0.55–0.8%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryMoisturizing

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase

Ascorbyl dipalmitate~0.55–0.8%

Formula

Irritation risk: Low

More about Ascorbyl dipalmitate

Hydrolyzed rice protein~0.5–0.75%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin. Might have some anti-oxidant properties

More about Hydrolyzed rice protein

Glycine soja protein~0.5–0.75%

Key active

Irritation risk: Low

Works for

CleansingMoisturizingEvens skin toneAnti-agingAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein

Hippophae rhamnoides oil~0.5–0.75%

Key activeIrritant · high

Irritation risk: High

Works for

MoisturizingAnti-oxidation

A good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.

More about Hippophae rhamnoides oil

Tamarindus indica seed polysaccharide~0.4–0.6%

Formula

Irritation risk: Low

More about Tamarindus indica seed polysaccharide

Porphyridium cruentum extract~0.4–0.6%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

A red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect

More about Porphyridium cruentum extract

Phospholipids~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Linoleic acid~0.5–0.75%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid

Linolenic acid~0.45–0.65%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingCleansingReduces irritationAnti-inflammatory

An emollient that helps soften the skin and calm down inflammation

More about Linolenic acid

Isomalt~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Isomalt

Glucose~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Pullulan~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan

Hydroxypropyl methylcellulose~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Hydroxypropyl methylcellulose

Hydroxypropyl cyclodextrin~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin

Lactoperoxidase~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. In theory, could support healthy skin's microbiome, but evidence of effectiveness in skin is lacking

More about Lactoperoxidase

Glucose oxidase~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Glucose oxidase

Citric acid~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Sclerotium gum~0.1–0.25%

Formula

Irritation risk: Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum

Xanthan gum~0.1–0.2%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Sodium phytate~0.05–0.1%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Ingredient list view

Water, Squalane, Glycerin, Cocoglycerides, Glyceryl triacetyl ricinoleate, Bellis perennis flower extract, C10-18 triglycerides, Candelilla/jojoba/rice bran polyglyceryl-3 esters, Glyceryl stearate, Cetearyl alcohol, Sodium stearoyl lactylate, Butyrospermum parkii butter, Palmitoyl tripeptide-38, Argania spinosa sprout cell extract, Leontopodium alpinum meristem cell culture, Superoxide dismutase, Ascorbyl dipalmitate, Hydrolyzed rice protein, Glycine soja protein, Hippophae rhamnoides oil, Tamarindus indica seed polysaccharide, Porphyridium cruentum extract, Phospholipids, Linoleic acid, Linolenic acid, Isomalt, Glucose, Pullulan, Hydroxypropyl methylcellulose, Hydroxypropyl cyclodextrin, Lactoperoxidase, Glucose oxidase, Citric acid, Sclerotium gum, Xanthan gum, Sodium phytate

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Amazon USPrice as of 10/28/2026 15:00 GMT

$100.00

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$100.00

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	NaturopathicaArgan & Peptide Wrinkle Remedy Eye CreamYOUR PRODUCT	M-61PowerGlow Eye Cream
Match	—	55%
Price	$100.00	$82.00−$18.00
Shared key ingredients	—	6 of 13
Key difference	—	Glycolic Acid
Irritancy	Medium	Medium
Drying alcohol	—	—
	View product	Shop

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Product summary

"Naturopathica - Argan & Peptide Wrinkle Remedy Eye Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (glycerin, isomalt, glucose, glycine soja protein and hydrolyzed rice protein) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (linoleic acid, hippophae rhamnoides oil, linolenic acid, squalane and c10-18 triglycerides) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

This moisturizer also contains Peptides (palmitoyl tripeptide-38 0.60% - 0.90%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 100.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

NaturopathicaArgan & Peptide Wrinkle Remedy Eye Cream

Buy at Dermstore$100.00 $100.00as of 10/28 15:00 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Dermstore$100.00 $100.00as of 10/28 15:00 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.