Naturium Multi-Peptide Advanced Serum

Naturium Multi-Peptide Advanced Serum

Efficacy83/100IrritancyMedium

Works for

Moisturizing
Copper palmitoyl heptapeptide-14, Acetyl hexapeptide-8 + 14 more
Works well
What the product description says
“Hydrates & plumps for a lifted effect”
Source: Naturium

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, diglycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper palmitoyl heptapeptide-14

Copper palmitoyl heptapeptide-14Hero· HumectantEffect: HighThe copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.~0.45–0.65%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.1–5.1%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2–2.5%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.2–1.5%
Helianthus annuus extractKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.75–1.1%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.55–0.8%
Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.45–0.65%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.45–0.7%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.4–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.35–0.65%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.35–0.6%
DiglycerinKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.55%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1.4–1.8%
LysolecithinEffect: LowLecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin~0.3–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%
Evens skin tone
Ferulic acid
May help
What the product description says
“smooths texture”
Source: Soko Glam

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: ferulic acid.

Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–0.7%
Anti-aging
Ferulic acid, Acetyl hexapeptide-8 + 3 more
May help
What the product description says
“Our powerful serum is formulated with an advanced multi-peptide blend, including encapsulated copper peptides and Argireline® Amplified peptide, to improve texture and reduce the appearance of fine lines and wrinkles.”
Source: Naturium

This product contains acetyl hexapeptide-8, copper palmitoyl heptapeptide-14, ferulic acid. There is some human evidence that these ingredients help reduce and prevent fine lines and wrinkles and improve skin elasticity and firmness, though it is smaller or less consistent than the evidence for the best anti-aging ingredients.

Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–0.7%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
Copper palmitoyl heptapeptide-14Key activeEffect: MediumThe copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.~0.45–0.65%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.2–1.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%
Anti-oxidation
Side benefit · Ferulic acid, Butyrospermum parkii butter + 3 more
Works well

This product contains antioxidants (ferulic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Ferulic acidKey activeEffect: HighA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–0.7%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.2–1.5%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.3–0.6%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.3%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Can it cause trouble?

Irritancy
1 strong irritant: Rosmarinus officinalis leaf extract
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
TetradecaneUsed as a fragrance. Can be irritatingHigh~1.4–1.7%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.3–0.6%est.
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.3–0.6%est.
Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.25–0.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.1–5.1%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.55–0.8%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.3–0.55%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.3–0.5%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.3–0.55%est.
Potassium sorbateA preservativeMedium~0.2–0.4%est.
Polyvinyl alcoholHelps improve the product textureMedium~0.2–0.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.3%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.2–1.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~4.2–5.2%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Caprylic/capric triglyceride~4.1–5.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Isopentyldiol~3.1–3.8%
Formula
Irritation risk
Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol
Ethylhexyl polyhydroxystearate~2.4–2.9%
Formula
Squalane~2–2.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Tetradecane~1.4–1.7%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Tetradecane
Glyceryl stearate citrate~1.4–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Butyrospermum parkii butter~1.2–1.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Polyglyceryl-3 stearate~0.95–1.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polyglyceryl-3 stearate
Helianthus annuus extract~0.75–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus extract
Oryza sativa bran extract~0.6–0.9%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Mannitol~0.55–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Phosphatidylcholine~0.55–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Ferulic acid~0.5–0.7%
Key active
Irritation risk
Low
Works for
Anti-oxidationEvens skin toneAnti-inflammatoryAnti-aging

A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%

More about Ferulic acid
Arginine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Acetyl hexapeptide-8~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Copper palmitoyl heptapeptide-14~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

The copper palmitoyl heptapeptide-14 is a synthetic peptide developed by ingredient supplier Infinitec, which claims that it can increase collagen production in skin when combined with Heptapeptide-15 Palmitate. The complex was tested in vitro (in a lab) and in a clinical test with 30 volunteers, but the latter wasn't placebo-controlled. The manufacturer reported wrinkle reduction after 28 days of use, but the details of the study aren't publicly available.

More about Copper palmitoyl heptapeptide-14
Palmitoyl sh-hexapeptide-13 serine sp amide
Not recognized
Hydrolyzed collagen~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen
Rosmarinus officinalis leaf extract~0.3–0.6%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Lactic acid/glycolic acid copolymer~0.3–0.6%
Formula
Glycerin~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Tocopherol~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Pullulan~0.3–0.6%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Lysolecithin~0.3–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Lecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin

More about Lysolecithin
Sclerotium gum~0.3–0.55%
Formula
Irritation risk
Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Dimethicone~0.4–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium phytate~0.3–0.55%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Diglycerin~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Diglycerin
Hydrogenated lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Silica~0.45–0.65%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Cetyl alcohol~0.35–0.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Hydroxyacetophenone~0.3–0.5%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Polysorbate 60~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sorbitan isostearate~0.3–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium benzoate~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Polyvinyl alcohol~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Helps improve the product texture

More about Polyvinyl alcohol
Decyl glucoside~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside
Xanthan gum~0.15–0.25%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Tocopheryl acetate~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Sodium chloride~0.15–0.25%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Citric acid~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Propanediol, Caprylic/capric triglyceride, Isopentyldiol, Ethylhexyl polyhydroxystearate, Squalane, Tetradecane, Glyceryl stearate citrate, Butyrospermum parkii butter, Polyglyceryl-3 stearate, Helianthus annuus extract, Oryza sativa bran extract, Mannitol, Phosphatidylcholine, Ferulic acid, Arginine, Acetyl hexapeptide-8, Copper palmitoyl heptapeptide-14, Unknown, Hydrolyzed collagen, Rosmarinus officinalis leaf extract, Lactic acid/glycolic acid copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium gum, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Dimethicone, Sodium phytate, Diglycerin, Hydrogenated lecithin, Silica, Cetyl alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan isostearate, Sodium hydroxide, Sodium benzoate, Potassium sorbate, Polyvinyl alcohol, Decyl glucoside, Xanthan gum, Tocopheryl acetate, Sodium chloride, Citric acid, Phenoxyethanol

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Amazon USPrice as of 11/14 09:08 GMT
$24.88
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$25.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NaturiumMulti-Peptide Advanced SerumYOUR PRODUCTREMEDY SCIENCEREMEDY for healthy agingMedik8Liquid PeptidesLancer SkincareLancer Triple Peptide Drops with Vitamin E + Niacinamide
Match—46%46%44%
Price$25.00$35.00+$10.00$68.00+$43.00$124.90+$99.90
Shared key ingredients—6 of 163 of 164 of 16
Key difference—RetinolPentapeptide-18Acetyl Tetrapeptide-2
Irritancy Medium Medium Low Medium
Drying alcohol————
View product Shop Shop Shop

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Product summary

"Naturium - Multi-Peptide Advanced Serum" is effective for: Moisturizing

This product could be helpful for: Anti-aging and Evens skin tone, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Peptides (copper palmitoyl heptapeptide-14 0.45% - 0.65% and acetyl hexapeptide-8 0.45% - 0.70%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Humectants (diglycerin 0.30% - 0.55%, glycerin 0.35% - 0.60%, hydrolyzed collagen 0.40% - 0.60%, copper palmitoyl heptapeptide-14 0.45% - 0.65%, acetyl hexapeptide-8 0.45% - 0.70%, arginine 0.45% - 0.70% and mannitol 0.55% - 0.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 25.00$ in the United States.

For a detailed price comparison: click here.

Naturium Multi-Peptide Advanced Serum
NaturiumMulti-Peptide Advanced Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.