NassifMD Dermaceuticals Age Defying Eye Renewal Serum with Dual Action Peptides

NassifMD Dermaceuticals Age Defying Eye Renewal Serum with Dual Action Peptides

Efficacy87/100IrritancyLow

Works for

Moisturizing
Acetyl hexapeptide-8, Acetyl tetrapeptide-5 + 9 more
Works well
What the product description says
“Deeply moisturizes with a lightweight serum that absorbs quickly”
Source: Nassif MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, peg-10 dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, acetyl tetrapeptide-5, panthenol

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Acetyl tetrapeptide-5Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.3–0.6%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~7.2–8.8%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.3–5.3%
PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1.7–2%
Peg-10 dimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that works to soften the upper layer of the skin and reduce its water loss~1.5–1.9%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.25–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.3–2.9%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.4%
Anti-aging
Acetyl hexapeptide-8, Acetyl tetrapeptide-5 + 1 more
May help
What the product description says
“Smooth crow’s feet, fine lines, and wrinkles both immediately and long-term”
Source: Nassif MD

This product contains acetyl hexapeptide-8, acetyl tetrapeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Acetyl tetrapeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%
Anti-oxidation
Not advertised by the brand · Camellia oleifera leaf extract, Caffeine + 2 more
Works well

This product contains antioxidants (camellia oleifera leaf extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Camellia oleifera leaf extractKey activeEffect: HighA plant extract that can help neutralize free radicals and reduce inflammation, even though it is not usually used in sufficient concentration in cosmetics~0.2–0.35%
CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.45–0.65%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.4–0.6%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%

Can it cause trouble?

Irritancy
7 flagged ingredients
Low risk
We flag 7 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.95–1.2%est.
Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.2–0.4%est.
Ci 16035A red dyeHigh~0.1–0.15%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.45–0.65%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.4–0.6%est.
Sodium sulfateUsed to improve the product consistency and stabilize formulationsMedium~0.15–0.3%est.
Ci 42090A colorant (dye)Medium~0.05–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ci 16035A red dye3/5~0.1–0.15%est.

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Cyclopentasiloxane~7.2–8.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Dimethicone~4.3–5.3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Dimethicone/vinyl dimethicone crosspolymer~3.2–3.9%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
Butylene glycol~2.3–2.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Ppg-12/smdi copolymer~2–2.5%
Formula
Irritation risk
Low

Used to create a nice product finish

More about Ppg-12/smdi copolymer
Polymethylsilsesquioxane~1.7–2%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Peg-10 dimethicone~1.5–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that works to soften the upper layer of the skin and reduce its water loss

More about Peg-10 dimethicone
Sodium chloride~1.2–1.5%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Pullulan~0.95–1.2%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Propanediol~0.65–1%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Phenoxyethanol~0.5–0.75%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Caffeine~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Tocopheryl acetate~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Panthenol~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Disteardimonium hectorite~0.3–0.6%
Formula
Irritation risk
Low

A type of clay that is used to thicken the product consistency

More about Disteardimonium hectorite
Acetyl tetrapeptide-5~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-5
Acetyl hexapeptide-8~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Tocopherol~0.25–0.5%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Allantoin~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Glycerin~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Chamomilla recutita flower extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract
Camellia oleifera leaf extract~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatory

A plant extract that can help neutralize free radicals and reduce inflammation, even though it is not usually used in sufficient concentration in cosmetics

More about Camellia oleifera leaf extract
Sodium phytate~0.2–0.35%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Ethylhexyl polyhydroxystearate~0.25–0.4%
Formula
Sodium hydroxide~0.15–0.3%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium carbonate~0.2–0.35%
Formula
Irritation risk
Low

Helps regulate product's pH

More about Sodium carbonate
Sodium sulfate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Used to improve the product consistency and stabilize formulations

More about Sodium sulfate
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ci 16035~0.1–0.15%
Comedogenic 3/5Irritant · high
Irritation risk
High
Comedogenicity
3/5

A red dye

More about Ci 16035
Ci 42090~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Ingredient list view

Water, Cyclopentasiloxane, Dimethicone, Dimethicone/vinyl dimethicone crosspolymer, Butylene glycol, Ppg-12/smdi copolymer, Polymethylsilsesquioxane, Peg-10 dimethicone, Sodium chloride, Pullulan, Propanediol, Phenoxyethanol, Caffeine, Tocopheryl acetate, Panthenol, Disteardimonium hectorite, Acetyl tetrapeptide-5, Acetyl hexapeptide-8, Tocopherol, Allantoin, Glycerin, Chamomilla recutita flower extract, Camellia oleifera leaf extract, Sodium phytate, Ethylhexyl polyhydroxystearate, Sodium hydroxide, Sodium carbonate, Sodium sulfate, Sodium benzoate, Ci 16035, Ci 42090

Compare prices

Retailers ranked by price — lowest first.

Nassif MD5 oz
$60.00
Buy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NassifMD DermaceuticalsAge Defying Eye Renewal Serum with Dual Action PeptidesYOUR PRODUCTDerm InstituteYouth Alchemy Eye SerumRapidLashRapidEye Firming Wrinkle SmootherM-61Hydraboost Eye Serum
Match—41%41%39%
Price$60.00$290.00+$230.00$18.99−$41.01$78.06+$18.06
Shared key ingredients—6 of 137 of 135 of 13
Key difference—RetinolRetinolPalmitoyl Tetrapeptide-7
Irritancy Low Medium High Low
Drying alcohol————
View product Shop Shop Shop

More alternatives: NIOD Fractionated Eye-Contour Concentrate SerumDIME Luminosity Eye Serum

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

"NassifMD Dermaceuticals - Age Defying Eye Renewal Serum with Dual Action Peptides" is effective for: Anti-oxidation and Moisturizing

This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Peptides (acetyl tetrapeptide-5 0.30% - 0.60% and acetyl hexapeptide-8 0.30% - 0.55%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Humectants (panthenol 0.30% - 0.60%, glycerin 0.25% - 0.45%, acetyl tetrapeptide-5 0.30% - 0.60% and acetyl hexapeptide-8 0.30% - 0.55%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 60.00$ in the United States.

For a detailed price comparison: click here.

NassifMD Dermaceuticals Age Defying Eye Renewal Serum with Dual Action Peptides
NassifMD DermaceuticalsAge Defying Eye Renewal Serum with Dual Action Peptides

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.