Murad Biome-Balancing Clear & Prevent Acne Treatment Serum

Murad Biome-Balancing Clear & Prevent Acne Treatment Serum

Efficacy100/100IrritancyHigh

Works for

Evens skin tone
Mandelic acid, Salicylic acid + 1 more
Works well
What the product description says
“Salicylic acid clears, mandelic acid smooths and evens tone, and Biome-Sensing Tech + glutamic acid empower your microbiome to generate what it needs to thrive for balanced, healthier-looking skin.”
Source: Murad

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: mandelic acid, salicylic acid

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Mandelic acidKey activeEffect: HighHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid~5.6–6.8%
Salicylic acidEffect: LowUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)1%
TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.4–0.65%
Anti-blemish
Salicylic acid, Mandelic acid + 3 more
Works well
What the product description says
“Clear all types of breakouts—from whiteheads to hormonal—and prevent acne relapses with this breakthrough serum.”
Source: Murad

This product can help reduce breakouts and clogged pores because it contains the following ingredient: salicylic acid. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: mandelic acid

Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)1%
Mandelic acidKey activeEffect: MediumHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid~5.6–6.8%
TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.4–0.65%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.35–0.6%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.6–0.85%
Exfoliation
Mandelic acid, Salicylic acid + 2 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: mandelic acid, salicylic acid.

Mandelic acidKey activeEffect: HighHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid~5.6–6.8%
Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)1%
UreaKey activeEffect: MediumNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.5–0.75%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.6–0.85%
Moisturizing
Not advertised by the brand · Urea, Glycerin + 14 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, erythritol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: urea

UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.5–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.3–4%
ErythritolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~2.5–3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.7–2%
Saccharide isomerateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~1–1.2%
Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.7–1.1%
InositolKey active· HumectantEffect: High~0.45–0.65%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.45–0.7%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.35–0.6%
Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.3–0.6%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.1–2.6%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.45–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.45%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.25%
Nelumbo nucifera flower extractEffect: Low, below effective dose~0.5–0.75%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.6–0.85%

Can it cause trouble?

Irritancy
3 strong irritants: Nelumbo nucifera flower extract, Ocimum basilicum flower/leaf extract + 1 more — patch-test recommended
High risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High1%
Mandelic acidHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acidHigh~5.6–6.8%est.
Nelumbo nucifera flower extract—High~0.5–0.75%est.
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.35–0.6%est.
Aloe barbadensis flower extractA plant extract that might have some anti-oxidant effectHigh~0.35–0.6%est.
Ocimum basilicum flower/leaf extractUsed as a fragrance. Canbe irritatingHigh~0.3–0.55%est.
Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.25–0.5%est.
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.3–0.55%est.
Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.3–0.6%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.1–2.6%est.
Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~1.6–1.9%est.
TaurineCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectivenessMedium~0.4–0.65%est.
Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.3–0.6%est.
Coccinia indica fruit extractA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skinMedium~0.3–0.55%est.
Solanum melongena fruit extractEggplant fruit extract. Might have some anti-oxidant effectMedium~0.3–0.55%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.15–0.25%est.
1,2-hexanediolA preservativeMedium~0.1–0.25%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.15–0.25%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.25%est.
ChlorphenesinA preservativeMedium~0.1–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.3–0.6%est.

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Salicylic acid1%
Hero · Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-inflammatoryExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~7.7–9.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Mandelic acid~5.6–6.8%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneExfoliationAnti-blemishAntibacterial

Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid

More about Mandelic acid
Glycerin~3.3–4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Erythritol~2.5–3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Erythritol
Pentylene glycol~2.1–2.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Sodium polyacryloyldimethyl taurate~1.6–1.9%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate
Dimethicone~1.7–2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium hydroxide~1.2–1.5%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Saccharide isomerate~1–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Saccharide isomerate
Glutamic acid~0.7–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Allantoin~0.6–0.85%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Punica granatum pericarp extract~0.55–0.85%
Formula
Nelumbo nucifera flower extract~0.5–0.75%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationMoisturizing
More about Nelumbo nucifera flower extract
Nymphaea caerulea flower extract~0.5–0.75%
Formula
Urea~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Yeast amino acids~0.5–0.75%
Formula
Trehalose~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Inositol~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Inositol
Taurine~0.4–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-blemishAnti-oxidationEvens skin tone

Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness

More about Taurine
Betaine~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Melia azadirachta leaf extract~0.35–0.6%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Melia azadirachta flower extract~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract
Corallina officinalis extract~0.3–0.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Coccinia indica fruit extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin

More about Coccinia indica fruit extract
Aloe barbadensis flower extract~0.35–0.6%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect

More about Aloe barbadensis flower extract
Solanum melongena fruit extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Eggplant fruit extract. Might have some anti-oxidant effect

More about Solanum melongena fruit extract
Ocimum basilicum flower/leaf extract~0.3–0.55%
Irritant · high
Irritation risk
High

Used as a fragrance. Canbe irritating

More about Ocimum basilicum flower/leaf extract
Curcuma longa root extract~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract
Ocimum sanctum leaf extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Maltodextrin~0.45–0.65%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Glyceryl polyacrylate~0.45–0.65%
Formula
Irritation risk
Low

Helps to create a nice product texture and spread the product more easily on the skin

More about Glyceryl polyacrylate
Polysilicone-11~0.45–0.65%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Butylene glycol~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Decyl glucoside~0.3–0.6%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside
Tetrasodium glutamate diacetate~0.2–0.4%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Citric acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium citrate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
1,2-hexanediol~0.1–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Leuconostoc/radish root ferment filtrate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Caprylyl glycol~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Chlorphenesin~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Ingredient list view

Salicylic acid, Water, Propanediol, Mandelic acid, Glycerin, Erythritol, Pentylene glycol, Sodium polyacryloyldimethyl taurate, Dimethicone, Sodium hydroxide, Saccharide isomerate, Glutamic acid, Allantoin, Punica granatum pericarp extract, Nelumbo nucifera flower extract, Nymphaea caerulea flower extract, Urea, Yeast amino acids, Trehalose, Inositol, Taurine, Betaine, Melia azadirachta leaf extract, Melia azadirachta flower extract, Corallina officinalis extract, Coccinia indica fruit extract, Aloe barbadensis flower extract, Solanum melongena fruit extract, Ocimum basilicum flower/leaf extract, Curcuma longa root extract, Ocimum sanctum leaf extract, Maltodextrin, Glyceryl polyacrylate, Polysilicone-11, Butylene glycol, Decyl glucoside, Tetrasodium glutamate diacetate, Citric acid, Sodium citrate, 1,2-hexanediol, Leuconostoc/radish root ferment filtrate, Caprylyl glycol, Chlorphenesin

Compare prices

Retailers ranked by price — lowest first.

Murad
$48.00
Buy
Sephora
$48.00
Buy
Sephora
Price unavailable
Check

Affiliate links

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MuradBiome-Balancing Clear & Prevent Acne Treatment SerumYOUR PRODUCTGLAMGLOWSuperserum by GlamglowFacetheoryPolyPep Collagen Boosting Serum S8 with ChroNOline Tetrapeptide, Polyhydroxy Acids and Centella AsiaticaUltraceuticalsUltra B2 Hydrating Serum
Match—90%86%85%
Price$48.00$56.00+$8.00——
Shared key ingredients—6 of 152 of 154 of 15
Key difference—Lactic AcidCaprooyl Tetrapeptide-3Niacinamide
Irritancy High Medium Low Low
Drying alcohol————
View product Shop Shop Shop

More alternatives: skintific 2% SALICYLIC ACID ANTI ACNE SERUMPure Blends Hydrating Serum

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

"Murad - Biome-Balancing Clear & Prevent Acne Treatment Serum" is effective for: Exfoliation, Anti-blemish, Moisturizing and Evens skin tone

Ingredient callouts

  • Exfoliating acids (mandelic acid 5.60% - 6.80%). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run.
  • Humectants (betaine 0.35% - 0.60%, inositol 0.45% - 0.65%, trehalose 0.45% - 0.70%, urea 0.50% - 0.75%, glutamic acid 0.70% - 1.10%, saccharide isomerate 1.00% - 1.20%, erythritol 2.50% - 3.00% and glycerin 3.30% - 4.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

About the brand

According to Cruelty-Free Kitty "Murad" is cruelty free, but its parent company is not.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
Murad Biome-Balancing Clear & Prevent Acne Treatment Serum
MuradBiome-Balancing Clear & Prevent Acne Treatment Serum

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.