Works for
Anti-agingAdenosine, Acetyl hexapeptide-8Works well
“Anti Wrinkle Effect Ampoule Origin”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
MoisturizingSide benefit the brand mentions · Acetyl hexapeptide-8, Glycerin + 5 moreWorks well
“Bestsellers include the Ultra Whitening Ampoule Origin that brightens skin and blurs blemishes, and the Big 3 Step Whitening Mask Pack that brightens and moisturizes skin while enhancing skin elasticity. All”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed collagen.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: hydrolyzed collagen.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8
Can it cause trouble?
Irritancy3 strong irritants: Rosa centifolia flower water, Zanthoxylum piperitum fruit extract + 1 more — patch-test recommendedHigh risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
Be the first — your take helps the next person decide.
Ingredients
Filter by role to see what each ingredient is doing.
Rosa centifolia flower water~26–38%
- Irritation risk
- High
Glycerin~5.4–8.1%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinSoluble collagen~5–7.6%
- Irritation risk
- Low
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
More about Soluble collagenNatto gum~3.9–5.8%
- Irritation risk
- Low
Wheat amino acids~2.4–3.6%
- Irritation risk
- Low
Panax ginseng root extract~2–3.1%
- Irritation risk
- High
A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating
More about Panax ginseng root extractGlycyrrhiza glabra root extract~1.3–2%
- Irritation risk
- Medium
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
More about Glycyrrhiza glabra root extractPlatycodon grandiflorus root extract~1.2–1.8%
- Irritation risk
- Low
Glycyrrhiza glabra root extract~0.95–1.4%
- Irritation risk
- Medium
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
More about Glycyrrhiza glabra root extractZingiber officinale extract~0.85–1.3%
- Irritation risk
- Low
Lonicera japonica flower extract~0.45–1.1%
- Irritation risk
- High
A plant extract that might help neutralize free radicals in skin. Can contain volalite oils and be irritating
More about Lonicera japonica flower extractZanthoxylum piperitum fruit extract~0.4–0.95%
- Irritation risk
- High
Plant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell
More about Zanthoxylum piperitum fruit extractPulsatilla koreana extract~0.35–0.8%
- Irritation risk
- Low
Citrus grandis fruit extract~0.2–0.75%
- Irritation risk
- High
Hydrolyzed collagen~0.45–1.1%
- Irritation risk
- Low
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
More about Hydrolyzed collagenSodium hyaluronate~0.15–0.55%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateHydroxyethylcellulose~0.2–0.75%
- Irritation risk
- Low
Used to thicken product formulations and create gel-like textures
More about HydroxyethylcelluloseTremella fuciformis sporocarp extract~0.1–0.35%
- Irritation risk
- Low
Mushroom extract that helps attract water to the upper layer of the skin
More about Tremella fuciformis sporocarp extractAcetyl hexapeptide-8~0.05–0.25%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Xanthan gum~0.05–0.15%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumAdenosine~0.05–0.1%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineDisodium edta~0.01–0.05%
Ingredient list view
Rosa centifolia flower water, Glycerin, Soluble collagen, Natto gum, Wheat amino acids, Panax ginseng root extract, Glycyrrhiza glabra root extract, Platycodon grandiflorus root extract, Glycyrrhiza glabra root extract, Unknown, Zingiber officinale extract, Lonicera japonica flower extract, Zanthoxylum piperitum fruit extract, Pulsatilla koreana extract, Citrus grandis fruit extract, Hydrolyzed collagen, Sodium hyaluronate, Unknown, Hydroxyethylcellulose, Unknown, Tremella fuciformis sporocarp extract, Acetyl hexapeptide-8, Xanthan gum, Adenosine, Disodium edta
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| MIGUHARAAnti Wrinkle Effect Ampoule OriginYOUR PRODUCT | CCLIMGLAM24K Gold Luxury Ampoule | EqqualberryNAD+ Peptide Boosting Serum | UNPAAtelo Firm Up Ampoule | |
|---|---|---|---|---|
| Match | — | 63% | 61% | 61% |
| Price | $49.00 | $36.70−$12.30 | $17.91−$31.09 | $25.40−$23.60 |
| Shared key ingredients | — | 5 of 7 | 5 of 7 | 5 of 7 |
| Key difference | — | Madecassoside | Acetyl Tetrapeptide-3 | Copper Tripeptide-1 |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Hanskin Collagen Peptide Hydra AmpouleWellderma PDRN Exosome Hydro Ampoule
Product summary
"MIGUHARA - Anti Wrinkle Effect Ampoule Origin" is effective for: Anti-aging and Moisturizing
Ingredient callouts
- Peptides (acetyl hexapeptide-8 0.05% - 0.25%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.05% - 0.10%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
- Humectants (acetyl hexapeptide-8 0.05% - 0.25%, tremella fuciformis sporocarp extract 0.10% - 0.30%, sodium hyaluronate 0.15% - 0.65%, hydrolyzed collagen 0.45% - 1.05%, soluble collagen 5.00% - 7.60% and glycerin 5.40% - 8.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 27.11$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 9 studies and safety reviews.
- 1
- 2Ginseng in Dermatology: A Reviewncbi.nlm.nih.gov
- 3
- 4
- 5
- 6Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
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