PRODUCT REVIEW
Medicube TXA + Niacinamide Capsule Cream
Buy from Amazon US $19.90
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Price as of 1/2/2026 1:36 GMT.
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Product summary
What can the product work for?
Evens skin tone
What does the product description say?
Release the TXA Red Capsule to refine skin tone and texture.
alpha-arbutin
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
glutathione
0.25% -
0.45%
Irritation risk:
Concentration: Effectiveness: HIGH
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
niacinamide
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
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Moisturizing
hydrolyzed sodium hyaluronate
0.05% -
0.15%
Irritation risk:
Concentration: Effectiveness: HIGH
Attracts water into the upper layer of the skin
niacinamide
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
ceramide np
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
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Anti-blemish
niacinamide
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
melia azadirachta leaf extract
0.25% -
0.45%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
Anti-aging
adenosine
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
niacinamide
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
ferulic acid
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
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Anti-oxidation
ferulic acid
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
glutathione
0.25% -
0.45%
Irritation risk:
Concentration: Effectiveness: HIGH
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
coccinia indica fruit extract
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin
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Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 3
Potential irritants
melia azadirachta leaf extract
0.25% -
0.45%
Irritation risk:
Works for:
Antibacterial,
Anti-blemish
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
Show more
Comodogenic ingredients
ethylhexyl palmitate
0.6% -
0.85%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
An emollient that helps soften the skin and create a nice product texture
cetearyl alcohol
0.55% -
0.8%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
User reviews (0)
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
4.1% -
5%
Irritation risk:
Works for:
Anti-aging,
Anti-blemish,
Evens skin tone,
Moisturizing,
Reduces irritation,
Anti-inflammatory,
Antibacterial,
Reduces redness
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
ferulic acid
0.2% -
0.4%
Irritation risk:
Works for:
Anti-oxidation,
Anti-inflammatory,
Evens skin tone,
Anti-aging
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
Show more
Potential irritants
melia azadirachta leaf extract
0.25% -
0.45%
Irritation risk:
Works for:
Antibacterial,
Anti-blemish
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
Show more
Comodogenic ingredients
ethylhexyl palmitate
0.6% -
0.85%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
An emollient that helps soften the skin and create a nice product texture
cetearyl alcohol
0.55% -
0.8%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
All ingredients
glycerin
4.7% -
5.7%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
niacinamide
4.1% -
5%
Irritation risk:
Works for:
Anti-aging,
Anti-blemish,
Evens skin tone,
Moisturizing,
Reduces irritation,
Anti-inflammatory,
Antibacterial,
Reduces redness
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Show more
Ingredient list view
Water, Glycerin, Niacinamide, Methylpropanediol, Propanediol, 1,2-hexanediol, Dipropylene glycol, Caprylic/capric triglyceride, Glyceryl glucoside, Butylene glycol, Arginine, Ethylhexyl palmitate, Carbomer, Cetearyl alcohol, Cetearyl olivate, Sorbitan olivate, C12-14 alketh-12, Ammonium acryloyldimethyltaurate/vp copolymer, Simethicone, Ethylhexylglycerin, Melia azadirachta flower extract, Melia azadirachta leaf extract, Adenosine, Polyacrylate-13, Disodium edta, Cyanocobalamin, Triethyl citrate, Betaine, Polyisobutene, Glyceryl stearate, Hydrolyzed sclerotium gum, Tranexamic acid, Abelmoschus esculentus fruit extract, Panthenol, Coccinia indica fruit extract, Corallina officinalis extract, Polysorbate 20, Sorbitan isostearate, Glutathione, Fragaria vesca fruit extract, Castanea crenata shell extract, Citrus junos peel extract, Betula platyphylla japonica leaf extract, Ricinus communis seed oil, Bisabolol, Ferulic acid, Cymbopogon citratus leaf oil, Illicium verum fruit/seed oil, Octyldodecanol, Hydrolyzed hyaluronic acid, 3-o-ethyl ascorbic acid, Sodium hyaluronate, Alpha-arbutin, Hydrogenated lecithin, Ceramide np, Hydroxypropyltrimonium hyaluronate, Caprylyl glycol, Sodium acetylated hyaluronate, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Potassium hyaluronate
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin
- Treatment of Xerosis with a Topical Formulation Containing Glyceryl Glucoside, Natural Moisturizing Factors, and Ceramide
- Melia azedarach
- Preliminary and Pharmacological Profile of Melia azedarach L.: An Overview
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trial
- Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis
- Citric Acid, Inorganic Citrate Salts and Alkyl Citrate Esters As Used in Cosmetics
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Glutathione as a skin whitening agent: Facts, myths, evidence and controversies
- Glutathione for skin lightening: a regnant myth or evidence-based verity?
- Glutathione for skin lightening for dermatologists and cosmetologists
- Final report on the safety assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate
- Castor Oil: Properties, Uses, and Optimization of Processing Parameters in Commercial Production
- Effect of ricinoleic acid in acute and subchronic experimental models of inflammation
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Ferulic Acid: Therapeutic Potential Through Its Antioxidant Property
- Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin
- Antioxidant Properties of Ferulic Acid and Its Possible Application
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Antioxidant Ability and Stability Studies of 3-O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitor
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin