Works for:
based on ingredients and %- Evens skin tone
- Moisturizing
- Anti-aging
- Anti-oxidation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 3
Key actives
Product Summary
"Medicube - TXA + Niacinamide Capsule Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Arginine, betaine, glycerin, glyceryl glucoside and hyaluronic acid in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide np, arginine, caprylic/capric triglyceride, ricinus communis seed oil and cetearyl alcohol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- We love that this moisturizer contains a good concentration of niacinamide 4.10% - 5.00%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
- Another benefit is that this moisturizer contain ceramides (ceramide np 0.20% - 0.40%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- Adenosine 0.20% - 0.40%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ferulic acid.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
Anti-oxidation
This product contains antioxidants (ferulic acid, glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin
Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants
A plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking
A plant extract that might be helpful to neutralize free radicals in skin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
Evens skin tone
What does the product description say?
Release the TXA Red Capsule to refine skin tone and texture.
Source: N/A
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: alpha-arbutin, glutathione, niacinamide, tranexamic acid
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: ferulic acid.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Moisturizing
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
arginine, betaine.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide
Attracts water into the upper layer of the skin
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants
Can support skin barrier function and reduce inflammation in skin
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Can help to restore skin barrier function and soften its upper layer
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Helps attract water to the upper layer of the skin and improves the product texture
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An emollient that helps soften the skin and create a nice product texture
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation
Helps attract water to the upper layer of the skin and can help improve skin barrier function
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Glycerin, Niacinamide, Methylpropanediol, Propanediol, 1,2-hexanediol, Dipropylene glycol, Caprylic/capric triglyceride, Glyceryl glucoside, Butylene glycol, Arginine, Ethylhexyl palmitate, Carbomer, Cetearyl alcohol, Cetearyl olivate, Sorbitan olivate, C12-14 alketh-12, Ammonium acryloyldimethyltaurate/vp copolymer, Simethicone, Ethylhexylglycerin, Melia azadirachta flower extract, Melia azadirachta leaf extract, Adenosine, Polyacrylate-13, Disodium edta, Cyanocobalamin, Triethyl citrate, Betaine, Polyisobutene, Glyceryl stearate, Hydrolyzed sclerotium gum, Tranexamic acid, Abelmoschus esculentus fruit extract, Panthenol, Coccinia indica fruit extract, Corallina officinalis extract, Polysorbate 20, Sorbitan isostearate, Glutathione, Fragaria vesca fruit extract, Castanea crenata shell extract, Citrus junos peel extract, Betula platyphylla japonica leaf extract, Ricinus communis seed oil, Bisabolol, Ferulic acid, Cymbopogon citratus leaf oil, Illicium verum fruit/seed oil, Octyldodecanol, Hydrolyzed hyaluronic acid, 3-o-ethyl ascorbic acid, Sodium hyaluronate, Alpha-arbutin, Hydrogenated lecithin, Ceramide np, Hydroxypropyltrimonium hyaluronate, Caprylyl glycol, Sodium acetylated hyaluronate, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Potassium hyaluronate
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin
- Treatment of Xerosis with a Topical Formulation Containing Glyceryl Glucoside, Natural Moisturizing Factors, and Ceramide
- Melia azedarach
- Preliminary and Pharmacological Profile of Melia azedarach L.: An Overview
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trial
- Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis
- Citric Acid, Inorganic Citrate Salts and Alkyl Citrate Esters As Used in Cosmetics
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Glutathione as a skin whitening agent: Facts, myths, evidence and controversies
- Glutathione for skin lightening: a regnant myth or evidence-based verity?
- Glutathione for skin lightening for dermatologists and cosmetologists
- Final report on the safety assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate
- Castor Oil: Properties, Uses, and Optimization of Processing Parameters in Commercial Production
- Effect of ricinoleic acid in acute and subchronic experimental models of inflammation
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Ferulic Acid: Therapeutic Potential Through Its Antioxidant Property
- Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin
- Antioxidant Properties of Ferulic Acid and Its Possible Application
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Antioxidant Ability and Stability Studies of 3-O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitor
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies