Medicube

Medicube TXA Niacinamide 15 Serum

Name: Medicube - TXA Niacinamide 15 Serum
Brand: Medicube

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Evens skin tone

Niacinamide, Tranexamic acid + 3 more

Works well

What the product description says

“DESCRIPTION Medicube TXA Niacinamide 15 Serum is infused with TXA 5% and Niacinamide 10% to target dark spots, hyperpigmentation and uneven skin tone. Helps improve skin clarity.”

Source: Lila Beauty

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide, tranexamic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: arbutin, ferulic acid.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.9–7.3%

Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~1.9–2.9%

ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~1.6–2.4%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.15–0.5%

Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.1–0.45%

Moisturizing

Niacinamide, Palmitoyl tripeptide-5 + 18 more

Works well

What the product description says

“Strengthens the skin barrier while providing deep hydration. Suitable for all skin types.”

Source: Lila Beauty

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": betaine, glycerin.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-5, hexapeptide-9, niacinamide, palmitoyl tripeptide-5

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.9–7.3%

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

Acetyl tetrapeptide-5Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.6–5.4%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.35–0.75%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.15–0.55%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.15–0.6%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.1–0.4%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.1–0.45%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.1–0.45%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.1–0.35%

Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.1–0.45%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.05–0.15%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.5–3.8%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.6%

PanthenolUnder-dosedHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.15–0.65%

Sodium hyaluronate crosspolymerUnder-dosedAttracts water into the upper layer of the skin~0.05–0.25%

Anti-oxidation

Side benefit · Arbutin, Glutathione + 5 more

Works well

This product contains antioxidants (ferulic acid, glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - arbutin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Ferulic acidKey activeEffect: HighA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.1–0.45%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.35–0.75%

Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.2–0.75%

Coccinia indica fruit extractEffect: LowA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin~0.1–0.5%

Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.1–0.45%

Anti-aging

Side benefit · Niacinamide, Adenosine + 5 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-5, ferulic acid, hexapeptide-9, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.35–0.75%

Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

Acetyl tetrapeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.1–0.4%

Anti-blemish

Side benefit · Niacinamide, Melia azadirachta leaf extract

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.2–0.75%

Can it cause trouble?

Irritancy

1 strong irritant: Rosa centifolia flower oil

Medium risk

We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.2–0.75%est.

Rosa centifolia flower oilAn essential oil. Can be irritatingHigh~0.1–0.45%est.

ArbutinBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutinMedium~1.6–2.4%est.

ChlorphenesinA preservativeMedium~0.16–0.32%est.

EthylhexylglycerinA preservativeMedium~0.6–1.35%est.

Disodium edtaStabilizes the product formulationMedium~0.3–0.75%est.

Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.2–0.75%est.

1,2-hexanediolA preservativeMedium~0.2–0.7%est.

Coccinia indica fruit extractA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skinMedium~0.1–0.5%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.6%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.15–0.5%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.05–0.25%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.1–0.45%est.

Alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%

Formula

Irritation risk: Low

Plain old water

More about Water

Niacinamide~4.9–7.3%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Glycerin~3.6–5.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Butylene glycol~2.5–3.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Tranexamic acid~1.9–2.9%

Key active

Irritation risk: Low

Works for

Evens skin toneMoisturizing

An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally

More about Tranexamic acid

Arbutin~1.6–2.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-oxidation

Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin

More about Arbutin

Diethoxyethyl succinate~1.3–2%

Formula

Irritation risk: Low

Helps dissolve other ingredients in the formulation

More about Diethoxyethyl succinate

Chlorphenesin~0.16–0.32%

Irritant · medium

Irritation risk: Medium

A preservative

More about Chlorphenesin

C12-14 alketh-12~0.95–1.45%

Formula

Irritation risk: Low

More about C12-14 alketh-12

Ethylhexylglycerin~0.6–1.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Xanthan gum~0.45–1.05%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Carbomer~0.4–0.9%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Adenosine~0.35–0.75%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Disodium edta~0.3–0.75%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Melia azadirachta leaf extract~0.2–0.75%

Irritant · high

Irritation risk: High

Works for

AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract

Melia azadirachta flower extract~0.2–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract

1,2-hexanediol~0.2–0.7%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Panthenol~0.15–0.65%

Under-dosed

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Cyanocobalamin~0.15–0.6%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Betaine~0.15–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Coccinia indica fruit extract~0.1–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin

More about Coccinia indica fruit extract

Rosa centifolia flower oil~0.1–0.45%

Irritant · high

Irritation risk: High

An essential oil. Can be irritating

More about Rosa centifolia flower oil

Ferulic acid~0.1–0.45%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-agingEvens skin toneAnti-inflammatory

A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%

More about Ferulic acid

Corallina officinalis extract~0.1–0.45%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract

Pentylene glycol~0.15–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Glutathione~0.15–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Hydrolyzed hyaluronic acid~0.1–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Hydrolyzed sodium hyaluronate~0.1–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Dimethylsilanol hyaluronate~0.1–0.45%

Formula

Irritation risk: Low

More about Dimethylsilanol hyaluronate

Hyaluronic acid~0.1–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Potassium hyaluronate~0.1–0.4%

Formula

Irritation risk: Low

More about Potassium hyaluronate

Sodium hyaluronate~0.1–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydroxypropyltrimonium hyaluronate~0.1–0.3%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Sodium hyaluronate crosspolymer~0.05–0.25%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Sodium hyaluronate dimethylsilanol~0.05–0.2%

Formula

Irritation risk: Low

More about Sodium hyaluronate dimethylsilanol

Sodium acetylated hyaluronate~0.05–0.15%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Acetyl tetrapeptide-5~0.05–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-5

Hexapeptide-9~0.05–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9

Palmitoyl tripeptide-5~0.05–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Ingredient list view

Water, Niacinamide, Glycerin, Butylene glycol, Tranexamic acid, Arbutin, Diethoxyethyl succinate, Chlorphenesin, C12-14 alketh-12, Ethylhexylglycerin, Xanthan gum, Carbomer, Adenosine, Disodium edta, Melia azadirachta leaf extract, Melia azadirachta flower extract, 1,2-hexanediol, Panthenol, Cyanocobalamin, Betaine, Coccinia indica fruit extract, Rosa centifolia flower oil, Ferulic acid, Corallina officinalis extract, Pentylene glycol, Glutathione, Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate, Dimethylsilanol hyaluronate, Hyaluronic acid, Potassium hyaluronate, Sodium hyaluronate, Hydroxypropyltrimonium hyaluronate, Sodium hyaluronate crosspolymer, Sodium hyaluronate dimethylsilanol, Sodium acetylated hyaluronate, Acetyl tetrapeptide-5, Hexapeptide-9, Palmitoyl tripeptide-5

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MedicubeTXA Niacinamide 15 SerumYOUR PRODUCT	EqqualberryVitamin illuminating Serum	BIODANCEPore tightening collagen ampoule	ArocellMilky Drop Ampoule
Match	—	87%	84%	83%
Price	—	$17.73	$34.32	—
Shared key ingredients	—	17 of 21	11 of 21	14 of 21
Key difference	—	3-O-Ethyl Ascorbic Acid	Allantoin	Sodium Ascorbyl Phosphate
Irritancy	Medium	Medium	Low	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Medicube - Buy TXA Niacinamide 15 Serum in Australia - Korean Skincare Online" is effective for: Evens skin tone, Moisturizing, Anti-aging and Anti-blemish

Ingredient callouts

A good concentration of Niacinamide (4.90% - 7.30%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
Peptides (palmitoyl tripeptide-5 0.05% - 0.15%, hexapeptide-9 0.05% - 0.15% and acetyl tetrapeptide-5 0.05% - 0.15%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.35% - 0.75%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Humectants (hexapeptide-9 0.05% - 0.15%, acetyl tetrapeptide-5 0.05% - 0.15%, sodium acetylated hyaluronate 0.05% - 0.15%, sodium hyaluronate 0.10% - 0.35%, hyaluronic acid 0.10% - 0.40%, hydrolyzed hyaluronic acid 0.10% - 0.45%, betaine 0.15% - 0.55% and glycerin 3.60% - 5.40%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 38.10A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 28 studies and safety reviews.

1
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
2
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
3
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
4
Effect of tranexamic acid on melasma: a clinical trial with histological evaluationonlinelibrary.wiley.com
5
Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skinonlinelibrary.wiley.com
6
The amelioration effect of tranexamic acid in wrinkles induced by skin drynesssciencedirect.com
7
Efficacy and possible mechanisms of topical tranexamic acid in melasmaonlinelibrary.wiley.com
8
Arbutin - Commentatymdedge.com
9
TOPICAL TREATMENT OF MELASMAncbi.nlm.nih.gov
10
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
11
Melia azedarachmdedge.com
12
Preliminary and Pharmacological Profile of Melia azedarach L.: An Overviewjapsonline.com
13
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
14
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
15
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MedicubeTXA Niacinamide 15 Serum

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