Medicube PDRN Pink Glutathione Serum Mist

Medicube PDRN Pink Glutathione Serum Mist

Efficacy100/100IrritancyMedium

Works for

Anti-aging
Niacinamide, Adenosine + 7 more
Works well
What the product description says
“Contains elasticity-boosting ingredients to combat visible signs of ageing.”
Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, biotinoyl tripeptide-1, hexapeptide-2, hexapeptide-9, myristoyl pentapeptide-17, tripeptide-1, tripeptide-3.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.45%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.4%
Biotinoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.4%
Tripeptide-3Key activeEffect: Medium~0.1–0.35%
Myristoyl pentapeptide-17Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Hexapeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Moisturizing
Niacinamide, Tripeptide-3 + 16 more
Works well
What the product description says
“Lightweight formula cools, soothes and hydrates skin.”
Source: Lila Beauty

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: hydroxyethyl urea, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, ricinus communis seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, biotinoyl tripeptide-1, hexapeptide-2, hexapeptide-9, myristoyl pentapeptide-17, niacinamide, tripeptide-1, tripeptide-3

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%
Tripeptide-3HeroEffect: High~0.1–0.35%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.45%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.4%
Biotinoyl tripeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.4%
Myristoyl pentapeptide-17HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Hexapeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Ricinus communis seed oilKey active· Emollient, OcclusiveEffect: HighA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency~1.9–2.8%
Hydroxyethyl ureaKey active· HumectantEffect: HighA derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients~1–1.6%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.35–0.75%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.1–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.85–1.25%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.35–0.85%
Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.15–0.65%
BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.1–0.45%
Rosa damascena flower waterEffect: Low, below effective doseUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating~0.1–0.45%
Exfoliation
Side benefit · Hydroxyethyl urea
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: hydroxyethyl urea.

Hydroxyethyl ureaKey activeEffect: HighA derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients~1–1.6%
Evens skin tone
Side benefit · Niacinamide, Glutathione + 1 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, hydroxyethyl urea, niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: paeonia lactiflora root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.1–0.45%
Paeonia lactiflora root extractEffect: LowA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking~0.2–0.8%
Anti-blemish
Side benefit · Niacinamide, Melia azadirachta leaf extract
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.15–0.6%
Anti-oxidation
Side benefit · Glutathione, Paeonia lactiflora root extract + 3 more
Works well

This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.1–0.45%
Paeonia lactiflora root extractEffect: LowA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking~0.2–0.8%
Eclipta prostrata extractEffect: LowA plant extract that might help neutralize free radicals in skin. It can be irritating~0.2–0.7%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%
Rosa damascena flower waterEffect: Low, below effective doseUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating~0.1–0.45%

Can it cause trouble?

Irritancy
2 strong irritants: Parfum, Rosa damascena flower water
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.7%est.
Eclipta prostrata extractA plant extract that might help neutralize free radicals in skin. It can be irritatingHigh~0.2–0.7%est.
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.15–0.6%est.
Rosa damascena flower waterUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritatingHigh~0.1–0.45%est.
1,2-hexanediolA preservativeMedium~1.9–2.8%est.
Ricinus communis seed oilA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistencyMedium~1.9–2.8%est.
EthylhexylglycerinA preservativeMedium~0.4–0.95%est.
Paeonia lactiflora root extractA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lackingMedium~0.2–0.8%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.15–0.65%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.1–0.45%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Collagen water~5.1–7.6%
Formula
Irritation risk
Low
More about Collagen water
1,2-hexanediol~1.9–2.8%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Dipropylene glycol~2.7–4%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
C13-15 alkane~2.1–3.2%
Formula
Irritation risk
Low

Helps dissolve other ingredients in the formula

More about C13-15 alkane
Ricinus communis seed oil~1.9–2.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatory

A plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency

More about Ricinus communis seed oil
Glycereth-26~1.5–2.3%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Niacinamide~1.3–1.9%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Hydroxyethyl urea~1–1.6%
Key active
Irritation risk
Low
Works for
ExfoliationMoisturizing

A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients

More about Hydroxyethyl urea
Butylene glycol~0.85–1.25%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Sodium dna~0.5–1.15%
Formula
Irritation risk
Low
More about Sodium dna
Ethylhexylglycerin~0.4–0.95%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sorbitol~0.35–0.85%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Sodium chloride~0.4–0.9%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Helianthus annuus seed oil~0.35–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Paeonia lactiflora root extract~0.2–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking

More about Paeonia lactiflora root extract
Candida bombicola/glucose/methyl rapeseedate ferment~0.4–0.9%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together and preserve the product formulation

More about Candida bombicola/glucose/methyl rapeseedate ferment
Parfum~0.15–0.7%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Eclipta prostrata extract~0.2–0.7%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might help neutralize free radicals in skin. It can be irritating

More about Eclipta prostrata extract
Melia azadirachta leaf extract~0.15–0.6%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Moringa oleifera seed oil~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Adenosine~0.15–0.55%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Rosa damascena flower water~0.1–0.45%
Irritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating

More about Rosa damascena flower water
Glutathione~0.1–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Biotin~0.1–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Biotinoyl tripeptide-1~0.1–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Biotinoyl tripeptide-1
Acetyl hexapeptide-8~0.1–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Tripeptide-1~0.1–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Tripeptide-3~0.1–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Tripeptide-3
Hexapeptide-9~0.05–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9
Myristoyl pentapeptide-17~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Myristoyl pentapeptide-17
Hexapeptide-2~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-2
Ingredient list view

Water, Collagen water, 1,2-hexanediol, Dipropylene glycol, C13-15 alkane, Ricinus communis seed oil, Glycereth-26, Niacinamide, Hydroxyethyl urea, Butylene glycol, Sodium dna, Ethylhexylglycerin, Sorbitol, Sodium chloride, Helianthus annuus seed oil, Paeonia lactiflora root extract, Candida bombicola/glucose/methyl rapeseedate ferment, Parfum, Eclipta prostrata extract, Melia azadirachta leaf extract, Moringa oleifera seed oil, Adenosine, Rosa damascena flower water, Glutathione, Biotin, Biotinoyl tripeptide-1, Acetyl hexapeptide-8, Tripeptide-1, Tripeptide-3, Hexapeptide-9, Myristoyl pentapeptide-17, Hexapeptide-2

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MedicubePDRN Pink Glutathione Serum MistYOUR PRODUCTSUNGBOON EDITORDeep Collagen Barrier Serum MistSWANICOCOPeptine Biome For Men All In One EssenceBliv:UCollagen Bouncing Toner
Match—76%75%71%
Price—$16.22$22.17$17.22
Shared key ingredients—6 of 147 of 145 of 14
Key difference—Copper Tripeptide-1Acetyl Dipeptide-1 Cetyl EsterCopper Tripeptide-1
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"Medicube - PDRN Pink Glutathione Serum Mist" is effective for: Evens skin tone, Anti-aging, Moisturizing, Exfoliation and Anti-blemish

Ingredient callouts

  • Peptides (hexapeptide-2 0.05% - 0.20%, myristoyl pentapeptide-17 0.05% - 0.20%, hexapeptide-9 0.05% - 0.25%, tripeptide-3 0.10% - 0.35%, tripeptide-1 0.10% - 0.45%, acetyl hexapeptide-8 0.10% - 0.40% and biotinoyl tripeptide-1 0.10% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.15% - 0.55%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Humectants (hexapeptide-9 0.05% - 0.25%, acetyl hexapeptide-8 0.10% - 0.40% and hydroxyethyl urea 1.00% - 1.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 34.95A$ in Australia and for 23.84$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 23 studies and safety reviews.

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Medicube PDRN Pink Glutathione Serum Mist
MedicubePDRN Pink Glutathione Serum Mist

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.