Works for:
based on ingredients and %- Moisturizing
- Evens skin tone
- Anti-oxidation
- Anti-aging
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"Medicube - Exosome Cica Ampoule" is effective for: Anti-aging, Moisturizing, Evens skin tone and Anti-blemish
Ingredient callouts
- A good concentration of Niacinamide (1.60% - 2.40%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.05% - 0.30%, madecassic acid 0.05% - 0.30%, asiaticoside 0.10% - 0.35% and madecassoside 0.35% - 0.85% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
- An effective concentration of Panthenol (pro-vitamin B5) - about 0.45% - 1.05%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
- Dipotassium Glycyrrhizate in this product (0.50% - 1.10%) can also further help improve the skin barrier. It might be able to calm down inflammation and reduce sensitivity. Dipotassium Glycyrrhizate is an active compound from the licorice root.
- In addition, this product contains Allantoin (0.45% - 1.05%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.
- Humectants (hyaluronic acid 0.10% - 0.35%, saccharide isomerate 0.15% - 0.65%, sodium hyaluronate 0.20% - 0.70%, biosaccharide gum-1 0.20% - 0.75%, panthenol 0.45% - 1.05%, glyceryl acrylate/acrylic acid copolymer 0.45% - 1.05%, betaine 1.20% - 1.80% and glycerin 4.70% - 7.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 26.01$ in the United States.
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Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, centella asiatica leaf extract, madecassoside.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Anti-oxidation
This product contains antioxidants (asiaticoside, madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Evens skin tone
What does the product description say?
This ampoule is enriched with 12 types of Cica ingredients, and 2% Niacinamide offers a soothing effect to irritated skin and brightens dark skin.
Source: Yesstyle
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Moisturizing
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": betaine, biosaccharide gum-1.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide, panthenol
Helps attract water to the upper layer of the skin and improves the product texture
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Helps attract water to the upper layer of the skin and might support the healthy skin microbiome
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Helps attract water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Softens the upper layer of the skin and can support skin barrier function
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used to preserve products, dissolve other ingredients and create a nice product texture
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin and improves the product texture
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
Softens the upper layer of the skin and can support skin barrier function
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin
Helps attract water to the upper layer of the skin and might support the healthy skin microbiome
Potential irritants
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to preserve products, dissolve other ingredients and create a nice product texture
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and improves the product texture
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Softens the upper layer of the skin and can support skin barrier function
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
Used to preserve products, dissolve other ingredients and create a nice product texture
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin and might support the healthy skin microbiome
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Ingredient list view
Centella asiatica leaf water, Water, Glycerin, Butylene glycol, Methylpropanediol, Glycereth-26, Niacinamide, 1,2-hexanediol, Betaine, Carbomer, Tromethamine, Glycereth-25 pca isostearate, Ethylhexylglycerin, Dipotassium glycyrrhizate, Allantoin, Glyceryl acrylate/acrylic acid copolymer, Panthenol, Gardenia florida fruit extract, Coptis japonica extract, Centella asiatica root extract, Centella asiatica leaf extract, Centella asiatica extract, Hydrogenated lecithin, Melaleuca alternifolia leaf water, Propanediol, Madecassoside, Glycyrrhiza uralensis extract, Ectoin, Dipropylene glycol, Centella asiatica leaf, Unknown, Caprylic/capric triglyceride, Biosaccharide gum-1, Pentylene glycol, Melaleuca alternifolia extract, Sodium hyaluronate, Vegetable amino acids, Saccharide isomerate, Lactobacillus ferment filtrate, Hydrolyzed vegetable protein, Hyaluronic acid, Houttuynia cordata extract, Asiaticoside, Madecassic acid, Asiatic acid
- Glycerol and the skin: holistic approach to its origin and functions
- Safety Assessment of Glycerin Ethoxylates as Used in Cosmetics
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Safety Assessment of Tromethamine as Used in Cosmetics
- Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
- Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.
- Profile of wound healing process induced by allantoin
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Allergic contact dermatitis from gardenia fruit
- VOLATILE CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF GARDENIA JASMINOIDES
- Centella asiatica in Dermatology: An Overview
- Contact dermatitis due to Madecassol
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Centella asiatica in Dermatology: An Overview
- Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes
- Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress
- Madecassoside Inhibits Melanin Synthesis by Blocking Ultraviolet-Induced Inflammation
- Stability Study of the Active Constituents in the Centella asiatica Extract Formulations
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Contact dermatitis due to Madecassol
- Centella asiatica in Dermatology: An Overview