Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Evens skin tone
- Anti-oxidation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
Based on the ingredient list, "Le Mieux - Bio Cell Rejuvenating Cream" can work well for skin moisturization. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl hexapeptide-8, galactomyces ferment filtrate, hyaluronic acid, hydrolyzed hyaluronic acid and saccharomyces lysate extract) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide eop, ceramide np, oenothera biennis oil, oryza sativa bran oil and plukenetia volubilis seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- As a plus, this moisturizer also contains Ceramides (ceramide np 0.35% - 0.85% and ceramide eop 0.40% - 0.90%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (palmitoyl tripeptide-5 0.35% - 0.80%, palmitoyl pentapeptide-4 0.40% - 0.90% and acetyl hexapeptide-8 0.45% - 1.00%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-oxidation
This product contains antioxidants (galactomyces ferment filtrate, tocotrienols, vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - tocopheryl linoleate also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Helps soften the upper layer of the skin and can support skin barrier function
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties
Moisturizing
What does the product description say?
Bio Cell Rejuvenating Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
galactomyces ferment filtrate, hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: plukenetia volubilis seed oil, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide eop, ceramide np, palmitoyl pentapeptide-4, palmitoyl tripeptide-5
A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes
Helps soften the upper layer of the skin and can support skin barrier function
Helps soften the upper layer of the skin and might have some anti-oxidant properties
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant oil that works as a good moisturizer by softening the upper layer of the skin. Might be helpful in reducing inflammation in skin and reducing blemishes due to the large content of linoleic acid
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
Helps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
Helps preserve products and creates a nice product texture
Might be somewhat helpful for attracting water to the upper layer of the skin
Used to create a nice product texture
An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-aging
What does the product description say?
Improves tone & texture • Reduces appearance of fine lines & wrinkles • Provides immediate & lasting moisture • Smooths & hydrates dry, sagging skin
Source: N/A
This product contains acetyl hexapeptide-8, galactomyces ferment filtrate, palmitoyl pentapeptide-4, palmitoyl tripeptide-5, tocotrienols, vitis vinifera seed extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Evens skin tone
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: galactomyces ferment filtrate.
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging | |
| Evens skin tone |
Total Promises Fulfilled score: 83/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
Helps soften the upper layer of the skin and can support skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Helps soften the upper layer of the skin and might have some anti-oxidant properties
A plant oil that works as a good moisturizer by softening the upper layer of the skin. Might be helpful in reducing inflammation in skin and reducing blemishes due to the large content of linoleic acid
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Attracts water into the upper layer of the skin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Helps soften the upper layer of the skin and can support skin barrier function
A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes
Helps preserve products and creates a nice product texture
Comedogenic ingredients
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
All ingredients
A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Might be somewhat helpful for attracting water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties
Helps soften the upper layer of the skin and might have some anti-oxidant properties
A plant oil that works as a good moisturizer by softening the upper layer of the skin. Might be helpful in reducing inflammation in skin and reducing blemishes due to the large content of linoleic acid
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Helps thicken the product formulation and create a gel-like texture
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
Helps soften the upper layer of the skin and can support skin barrier function
A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes
Used to thicken product formulations and create gel-like textures
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
An aromatic blend of unspecified and possibly irritating ingredients
Helps preserve products and creates a nice product texture
Helps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin
Ingredient list view
Galactomyces ferment filtrate, Sodium hyaluronate, Oryza sativa bran water, Hyaluronic acid, Zinc hydrolyzed hyaluronate, Hydroxypropyltrimonium hyaluronate, Sodium hyaluronate dimethylsilanol, Sodium hyaluronate crosspolymer, C12-13 alkyl glyceryl hydrolyzed hyaluronate, Hydrolyzed hyaluronic acid, Sodium acetylated hyaluronate, Ascorbyl propyl hyaluronate, Acetyl hexapeptide-8, Oligopeptide-123, Oligopeptide-25, Dipalmitoyl hydroxyproline, Palmitoyl pentapeptide-4, Palmitoyl tripeptide-5, Ceramide eop, Ceramide np, Squalane, Saccharomyces lysate extract, Phospholipids, Glyceryl polymethacrylate, Simmondsia chinensis seed oil, Argania spinosa kernel oil, Oryza sativa bran oil, Plukenetia volubilis seed oil, Butyrospermum parkii butter, Cetyl alcohol, Tocotrienols, Tocopheryl linoleate, Sodium carboxymethyl beta-glucan, Vitis vinifera seed extract, Oenothera biennis oil, Rosa canina seed oil, Hydroxyethylcellulose, Tocopherol, Parfum, Caprylyl glycol, Ethylhexylglycerin, Undecylenoyl glycine, Capryloyl glycine
- Effects of galactomyces ferment filtrate on epidermal barrier marker caspase-14 in human skin cells.
- Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner
- The Effects of Essence-Formed Cosmetic Ingredients Containing the Galactomyces Ferment Filtrate on Skin Improvements in Keratinization, Pores, Sebum Excretion, Brightness and Acne
- Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate downregulate senescence marker CDKN2A/p16INK4A via NRF2 activation in keratinocytes
- Galactomyces Ferment Filtrate Suppresses Reactive Oxygen Species Generation and Promotes Cellular Redox Balance in Human Melanocytes via Nrf2-ARE Pathway
- Galactomyces Ferment Filtrate Suppresses Melanization and Oxidative Stress in Epidermal Melanocytes
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Use of Probiotics for Dermal Applications
- Natural vegetable fats in the prevention of irritant contact dermatitis
- Study on the Composition of Rice Bran Oil and Its Higher Free Fatty Acids Value
- Chemical composition of Sacha Inchi ( Plukenetia volubilis L.) seeds and characteristics of their lipid fraction
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside study
- Tocotrienols: Vitamin E beyond tocopherols
- Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)
- Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics
- An Epidemic Outbreak of Papular and Follicular Contact Dermatitis to Tocopheryl Linoleate in Cosmetics. Swiss Contact Dermatitis Research Group
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics
- The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healing
- Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update
- Nutrient composition of rose (Rosa canina L.) seed and oils
- Characterization of Rosehip (Rosa canina L.) Seed and Seed Oil
- Bioactive ingredients of rose hips (Rosa canina L) with special reference to antioxidative and anti-inflammatory properties: in vitro studies
- Vitamin E in dermatology
- Vitamin E and Skin Health