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Lancôme Advance Genifique Serum
Lancôme

Lancôme Advance Genifique Serum

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Ascorbyl glucoside, Adenosine + 2 more
Works well
What the product description says
“Super lightweight, the anti-ageing serum melts quickly into skin, quenching and plumping to minimise the appearance of lines and wrinkles.”
Source: Lookfantastic

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ascorbyl glucoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~1.7–2.1%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.65%
Salicyloyl phytosphingosineEffect: LowHelps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking~0.25–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.3%
Moisturizing
Salicyloyl phytosphingosine, Bifida ferment lysate + 14 more
Works well
What the product description says
“Super lightweight, the anti-ageing serum melts quickly into skin, quenching and plumping to minimise the appearance of lines and wrinkles.”
Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: salicyloyl phytosphingosine

Salicyloyl phytosphingosineHero· HumectantEffect: HighHelps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking~0.25–0.45%
Bifida ferment lysateKey activeEffect: HighConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~6.1–7.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.4–3%
LactobacillusKey activeEffect: HighA non-living ingredient made by fermentation with the bacteria Lactobacillus. It can help attract water to the upper layer of the skin and might help reduce inflammation~1.4–1.7%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.9–1.1%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.65%
Faex extractKey activeEffect: HighYeast extract. Helps attract water to the upper layer of the skin~0.35–0.65%
Alpha-glucan oligosaccharideKey activeEffect: HighHelps attract water to the upper layer of the skin~0.25–0.5%
Polymnia sonchifolia root juiceEffect: LowA plant extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties~0.3–0.55%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.4%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.25–0.5%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.2–0.4%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.15–0.3%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.1–0.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.3%
Anti-oxidation
Not advertised by the brand · Bifida ferment lysate, Ascorbyl glucoside + 2 more
May help

This product contains antioxidants (ascorbyl glucoside, bifida ferment lysate) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Bifida ferment lysateKey activeEffect: MediumConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~6.1–7.5%
Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~1.7–2.1%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.65%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.3%
Evens skin tone
Not advertised by the brand · Ascorbyl glucoside, Bifida ferment lysate
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: ascorbyl glucoside, bifida ferment lysate.

Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~1.7–2.1%
Bifida ferment lysateEffect: LowConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~6.1–7.5%

Can it cause trouble?

Irritancy
5 strong irritants: Alcohol denat., Limonene + 3 more — patch-test recommended
High risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~3.1–3.8%est.
Polymnia sonchifolia root juiceA plant extract that helps attract water to the upper layer of the skin and might have some anti-oxidant propertiesHigh~0.3–0.55%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.4%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.2–0.4%est.
Rosa gallica flower extract—High~0.1–0.2%est.
CitronellolA fragrance. Can be irritatingHigh~0.05–0.1%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05%est.
Hydroxyethylpiperazine ethane sulfonic acidUsed to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical productsMedium~1.9–2.3%est.
Ascorbyl glucosideA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsMedium~1.7–2.1%est.
Peg-20 methyl glucose sesquistearateHelps oil and water mix togetherMedium~0.45–0.65%est.
Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~0.4–0.6%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.4%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.25%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Alternatives
Cheaper, or higher on efficacy
Revitalift Concentrated Serum
L'Oréal Paris Revitalift Concentrated Serum
Cheaper62% match
$15.06
LiftActiv Supreme Eyes & Lashes Serum
Vichy LiftActiv Supreme Eyes & Lashes Serum
Cheaper55% match
$29.90
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Bifida ferment lysate~6.1–7.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Alcohol denat.~3.1–3.8%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Dimethicone~2.4–3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Hydroxyethylpiperazine ethane sulfonic acid~1.9–2.3%
Irritant · medium
Irritation risk
Medium
Works for
Exfoliation

Used to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical products

More about Hydroxyethylpiperazine ethane sulfonic acid
Ascorbyl glucoside~1.7–2.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidationEvens skin tone

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about Ascorbyl glucoside
Lactobacillus~1.4–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

A non-living ingredient made by fermentation with the bacteria Lactobacillus. It can help attract water to the upper layer of the skin and might help reduce inflammation

More about Lactobacillus
Tocopherol~1.1–1.3%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Sodium hyaluronate~0.9–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Sodium hydroxide~0.65–0.95%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Phenoxyethanol~0.45–0.7%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Adenosine~0.45–0.65%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Faex extract~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Yeast extract. Helps attract water to the upper layer of the skin

More about Faex extract
Peg-20 methyl glucose sesquistearate~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-20 methyl glucose sesquistearate
Peg-60 hydrogenated castor oil~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil
Polymnia sonchifolia root juice~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Moisturizing

A plant extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties

More about Polymnia sonchifolia root juice
Maltodextrin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Salicyloyl phytosphingosine~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

Helps attract water to the upper layer of the skin. Might have anti-aging benefits but solid study data is lacking

More about Salicyloyl phytosphingosine
Ammonium polyacryloyldimethyl taurate~0.25–0.45%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Ammonium polyacryloyldimethyl taurate
Limonene~0.2–0.4%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Mannose~0.2–0.4%
Formula
Irritation risk
Low
More about Mannose
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Pentylene glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Propylene glycol~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Caprylyl glycol~0.25–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Alpha-glucan oligosaccharide~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Alpha-glucan oligosaccharide
Sorbitol~0.15–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Disodium edta~0.1–0.25%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Rosa gallica flower extract~0.1–0.2%
Irritant · high
Irritation risk
High
More about Rosa gallica flower extract
Octyldodecanol~0.1–0.2%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Citronellol~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Parfum~0.05%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Bifida ferment lysate, Glycerin, Alcohol denat., Dimethicone, Hydroxyethylpiperazine ethane sulfonic acid, Ascorbyl glucoside, Lactobacillus, Tocopherol, Sodium hyaluronate, Sodium hydroxide, Sodium benzoate, Phenoxyethanol, Adenosine, Faex extract, Peg-20 methyl glucose sesquistearate, Peg-60 hydrogenated castor oil, Polymnia sonchifolia root juice, Maltodextrin, Salicyloyl phytosphingosine, Ammonium polyacryloyldimethyl taurate, Limonene, Mannose, Xanthan gum, Pentylene glycol, Propylene glycol, Caprylyl glycol, Alpha-glucan oligosaccharide, Sorbitol, Disodium edta, Rosa gallica flower extract, Octyldodecanol, Citronellol, Parfum

Compare prices

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Amazon USPrice as of 11/2 18:36 GMT
$75.65
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
LancômeAdvance Genifique SerumYOUR PRODUCTBIOTHERMLIFE PLANKTON™ ELIXIR ANTI-AGING SERUML'Oréal ParisRevitalift Concentrated SerumVichyLiftActiv Supreme Eyes & Lashes Serum
Match—72%62%55%
Price$75.65—$15.06−$60.59$29.90−$45.75
Shared key ingredients—9 of 128 of 126 of 12
Key difference—Hyaluronic AcidRetinyl Palmitate—
Irritancy High Medium High Medium
Drying alcohol Contains drying alcohol Contains drying alcohol Contains drying alcohol Contains drying alcohol
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

  1. 1
    Bifidobacterium longumlysate, a new ingredient forreactive skinonlinelibrary.wiley.com
  2. 2
    Use of Probiotics for Dermal Applicationsresearchgate.net
  3. 3
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  4. 4
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  5. 5
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  6. 6
    Oxidative DNA damage induced by HEPES (2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid) buffer in the presence of Au(III)researchgate.net
Lancôme Advance Genifique Serum
LancômeAdvance Genifique Serum
Buy on Amazon$75.65 · as of 11/2 18:36 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$75.65 · as of 11/2 18:36 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.