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“Toleriane Ultra Overnight Moisturiser”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
carnosine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide
This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

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Filter by role to see what each ingredient is doing.
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneActs as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
More about Butyrospermum parkii butterUsed to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeUsed to create a thicker product consistency
More about Ammonium polyacryloyldimethyl taurateA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss
More about PolymethylsilsesquioxaneHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
More about AllantoinHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
More about Glyceryl acrylate/acrylic acid copolymerA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
More about DimethiconolUsed to thicken the product's consistency
More about Aluminum starch octenylsuccinateA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
More about CarnosineCan work as an exfoliant but is typically used to adjust the product pH
More about Citric acidA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl dipeptide-1 cetyl esterUsed to create a thicker product consistency
More about Xanthan gumUsed to dissolve other ingredients and to improve smell of products. It could be irritating
More about T-butyl alcoholPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolWater, Glycerin, Squalane, Propanediol, Butylene glycol, Butyrospermum parkii butter, Pentylene glycol, Niacinamide, Dimethicone, Ammonium polyacryloyldimethyl taurate, Polymethylsilsesquioxane, Polysorbate 20, Allantoin, Glyceryl acrylate/acrylic acid copolymer, Dimethiconol, Aluminum starch octenylsuccinate, Carnosine, Disodium edta, Citric acid, Acetyl dipeptide-1 cetyl ester, Xanthan gum, T-butyl alcohol, Toluene sulfonic acid, Tocopherol
Retailers ranked by price — lowest first.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| La Roche-PosayToleriane Ultra Overnight MoisturiserYOUR PRODUCT | UltraceuticalsUltra Calming Moisturiser Cream | OleHenriksenStrength Trainer Peptide Boost Moisturiser | Dr.Reju-AllAdvanced LC-Ceramide Barrier Cream | |
|---|---|---|---|---|
| Match | — | 89% | 78% | 78% |
| Price | $22.47 | $76.54+$54.07 | $43.11+$20.64 | $25.65+$3.18 |
| Shared key ingredients | — | 6 of 11 | 5 of 11 | 6 of 11 |
| Key difference | — | Ceramide Np | Acetyl Octapeptide-3 | Madecassoside |
| Irritancy | Low | Low | High | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Based on the ingredients included, "La Roche-Posay - Toleriane Ultra Overnight Moisturiser" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. La Roche-Posay - Toleriane Ultra Overnight Moisturiser ticks this box. Carnosine, glycerin, glyceryl acrylate/acrylic acid copolymer and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (butyrospermum parkii butter, dimethicone, dimethiconol, squalane and pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
The product retails from 39.23A$ up to 46.00A$ in Australia and from 20.00£ up to 21.00£ in the United Kingdom.
For a detailed price comparison: click here.
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
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