La Roche-Posay Hyalu B5 Hyaluronic Moisturiser

La Roche-Posay Hyalu B5 Hyaluronic Moisturiser

Efficacy66/100IrritancyMedium
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Works for

2 of 3 advertised claims delivered

Anti-aging
2 ingredients credited for this claim
Strong support
What the product description says
“La Roche-Posay Hyalu B5 Anti-Wrinkle Care Repairing Replumping 40ml is a cream that acts on wrinkles, loss of volume and elasticity.Its unique hydrating and plumping formula combines two types of pure hyaluronic acid and vitamin B5.”
Source: Cocoon Center

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.8%
Moisturizing
12 ingredients credited for this claim
Strong support
What the product description says
“Hyalu B5 Hyaluronic Moisturiser”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, peg-10 dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

Peg-10 dimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that works to soften the upper layer of the skin and reduce its water loss~0.5–1.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.7–5.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.1–6.1%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.75%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.2–0.75%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~1.7–2.5%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.1–1.6%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.45%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~2–3.1%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~2.8–4.2%
Propylene carbonateEffect: LowIs used to dissolve other ingredients and create nice product texture~0.1–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.8%
Anti-blemish
No ingredient credited for this claim
No support
What the product description says
“Also of note is the Effaclar Duo+ M Serum, a salicylic acid-rich serum additionally infused with niacinamide to clear pores and deliver radiance.”
Source: Yesstyle

Effective ingredients missing or their concentration is too low.

Can it cause trouble?

Irritancy
2 strong irritants: Alcohol denat., Parfum
Medium risk
We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~2–3.1%est.
Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~1.7–2.5%est.
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~1.5–2.2%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.1%est.
Dimethicone/peg-10/15 crosspolymerHelps oil and water mix togetherMedium~0.45–1%est.
Hydroxyethylpiperazine ethane sulfonic acidUsed to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical productsMedium~0.35–0.85%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.15–0.5%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.1–6.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~3.7–5.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Hydrogenated polyisobutene~2.8–4.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Propylene glycol~2–3.1%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Hydroxypropyl tetrahydropyrantriol~1.7–2.5%
Key activeIrritant · high
Irritation risk
High
Works for
Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol
Alcohol denat.~1.5–2.2%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Propanediol~1.3–2%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Panthenol~1.1–1.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Synthetic wax~0.9–1.35%
Formula
Irritation risk
Low

Used to stabilize product formulations and thicken product consistency

More about Synthetic wax
Nylon-12~0.8–1.25%
Formula
Irritation risk
Low

Used to create a nice product consistency

More about Nylon-12
Peg-10 dimethicone~0.5–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that works to soften the upper layer of the skin and reduce its water loss

More about Peg-10 dimethicone
Dimethicone/peg-10/15 crosspolymer~0.45–1%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Dimethicone/peg-10/15 crosspolymer
Hydroxyethylpiperazine ethane sulfonic acid~0.35–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Exfoliation

Used to regulate product's pH, but can be also used as an exfoliator when included in higher concentrations. There is a controversy about whether it can generate free radicals and induce skin cell damage when used in topical products

More about Hydroxyethylpiperazine ethane sulfonic acid
Tocopherol~0.35–0.8%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Sodium polyacrylate~0.35–0.85%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Sodium hyaluronate~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Hydrolyzed hyaluronic acid~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Sodium citrate~0.15–0.5%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Phenoxyethanol~0.1–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Adenosine~0.1–0.45%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Propylene carbonate~0.1–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Is used to dissolve other ingredients and create nice product texture

More about Propylene carbonate
Dipropylene glycol~0.05–0.25%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Disteardimonium hectorite~0.05–0.25%
Formula
Irritation risk
Low

A type of clay that is used to thicken the product consistency

More about Disteardimonium hectorite
Disodium edta~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Parfum~0.05–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
(code f.i.l. : c213954/1)
Not recognized
Ingredient list view

Water, Glycerin, Dimethicone, Hydrogenated polyisobutene, Propylene glycol, Hydroxypropyl tetrahydropyrantriol, Alcohol denat., Propanediol, Panthenol, Synthetic wax, Nylon-12, Peg-10 dimethicone, Dimethicone/peg-10/15 crosspolymer, Hydroxyethylpiperazine ethane sulfonic acid, Tocopherol, Sodium polyacrylate, Sodium hyaluronate, Hydrolyzed hyaluronic acid, Sodium citrate, Phenoxyethanol, Adenosine, Chlorphenesin, Propylene carbonate, Dipropylene glycol, Disteardimonium hectorite, Disodium edta, Parfum, Unknown

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Amazon USPrice as of 10/18/2026 18:04 GMT
$35.99
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$70.30
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
La Roche-PosayHyalu B5 Hyaluronic MoisturiserYOUR PRODUCTDr. Reju-AllAdvanced PDRN Rejuvenating Cream 20gBIOTHERMBlue Therapy Amber Algae Revitalize Nutrition and Radiance Day CreamHeimishBlack Rose Hydra Plumping Sorbet Cream 50ml
Match—63%60%59%
Price$34.50$54.14+$19.64$71.55+$37.05$37.68+$3.18
Shared key ingredients—6 of 116 of 117 of 11
Key difference—NiacinamideCapryloyl Salicylic AcidCopper Tripeptide-1
Irritancy Medium Low Medium Medium
Drying alcohol Contains drying alcohol ———
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Product summary

Judging from the ingredient list, "La Roche-Posay - Hyalu B5 Hyaluronic Moisturiser" works well for improving skin hydration This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Panthenol, glycerin, hydrolyzed hyaluronic acid, sodium hyaluronate and propylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Dimethicone, peg-10 dimethicone and hydrogenated polyisobutene in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Adenosine 0.10% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • An effective concentration of Panthenol (pro-vitamin B5) - about 1.10% - 1.60%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 56.06A$ in Australia, from 29.89£ up to 32.00£ in the United Kingdom, for 47.00CA$ in Canada and from 34.50$ up to 70.30$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 20 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
La Roche-Posay Hyalu B5 Hyaluronic Moisturiser
La Roche-PosayHyalu B5 Hyaluronic Moisturiser

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As an Amazon Associate, WIMJ earns from qualifying purchases.