Klore

Klore Stem cell PSE

Name: Klore - Stem cell PSE
Brand: Klore

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Niacinamide, Panthenol + 26 more

Works well

What the product description says

“Stem cell PSE is a brightening/anti-wrinkle dual functional product With quadruple hyaluronic acid ingredients that help to build up a strong, tight moisturizing barrier from the deepest layer of the skin.”

Source: N/A

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, sodium acetylated hyaluronate.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, madecassoside, niacinamide, palmitoyl pentapeptide-4, panthenol

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.3–5.2%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.5–0.7%

MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.25–0.45%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1–1.2%

Lactobacillus/soybean ferment extractKey activeEffect: MediumA fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking~0.3–0.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.25–0.4%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%

Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.4%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.25–0.45%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.2–0.4%

Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.2–0.4%

AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.2–0.35%

Avena sativa meal extractKey activeEffect: HighA type of oatmeal extract. Helps restore skin barrier and has antioxidant properties~0.2–0.4%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%

Vitis vinifera fruit extractKey activeEffect: MediumA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.2–0.4%

Leontopodium alpinum callus culture extractKey active· HumectantEffect: MediumA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.2–0.4%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~1.6–1.9%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.45–0.65%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.25–0.5%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.25–0.45%

Portulaca oleracea extract· HumectantEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.25–0.5%

Scutellaria baicalensis root extract· HumectantEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.15–0.3%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%

Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%

Anti-aging

Niacinamide, Adenosine + 7 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, asiaticoside, copper tripeptide-1, madecassoside, palmitoyl pentapeptide-4.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.3–5.2%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1–1.2%

MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.25–0.45%

AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.2–0.35%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Evens skin tone

Niacinamide, Madecassoside + 2 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.25–0.45%

Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%

Anti-blemish

Side benefit · Niacinamide, Salix alba bark extract + 1 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Salix alba bark extractEffect: Low, below effective doseA plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect~0.25–0.5%

Anti-oxidation

Side benefit · Madecassoside, Camellia japonica flower extract + 14 more

Works well

This product contains antioxidants (asiaticoside, madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia japonica flower extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.25–0.45%

Camellia japonica flower extractKey activeEffect: MediumA plant extract that might help neutralize free radicals in skin~0.25–0.45%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1–1.2%

Portulaca oleracea extractEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.25–0.5%

Origanum vulgare leaf extractEffect: LowA plant extract. Can have an anti-oxidant effect, but can also contain irritants~0.25–0.4%

Leontopodium alpinum callus culture extractEffect: LowA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.2–0.4%

Vaccinium angustifolium fruit extractEffect: LowA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking~0.2–0.35%

Spinacia oleracea leaf extractEffect: LowA plant extract that might have some anti-oxidant properties~0.2–0.4%

Vitis vinifera fruit extractEffect: LowA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.2–0.4%

Anemarrhena asphodeloides root extractEffect: LowA plant extract that might have some anti-oxidant properties~0.15–0.3%

Scutellaria baicalensis root extractEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.15–0.3%

Brassica oleracea italica extractEffect: Low, below effective doseMight have some anti-inflammatory properties but research is lacking~0.25–0.4%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%

Can it cause trouble?

Irritancy

27 flagged ingredients — patch-test recommended

High risk

We flagged 27 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~7.4–9%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.5–0.8%est.

Salix alba bark extractA plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effectHigh~0.25–0.5%est.

Origanum vulgare leaf extractA plant extract. Can have an anti-oxidant effect, but can also contain irritantsHigh~0.25–0.4%est.

Cinnamomum cassia bark extractUsed as a fragrance. Can be irritatingHigh~0.25–0.45%est.

Scutellaria baicalensis root extractA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant propertiesHigh~0.15–0.3%est.

Chamaecyparis obtusa leaf extractUsed as a fragranceHigh~0.2–0.35%est.

Camellia japonica flower extractA plant extract that might help neutralize free radicals in skinHigh~0.25–0.45%est.

Butylphenyl methylpropionalA fragrance. Can trigger allergic reactions and be irritatingHigh~0.1–0.15%est.

Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.1–0.15%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~2.2–2.7%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~1.6–1.9%est.

PvpHelps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skinMedium~1.3–1.6%est.

Disodium edtaStabilizes the product formulationMedium~0.5–1%est.

Portulaca oleracea extractA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skinMedium~0.25–0.5%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.25–0.45%est.

1,2-hexanediolA preservativeMedium~0.2–0.35%est.

Brassica oleracea italica extractMight have some anti-inflammatory properties but research is lackingMedium~0.25–0.4%est.

Vaccinium angustifolium fruit extractA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lackingMedium~0.2–0.35%est.

Spinacia oleracea leaf extractA plant extract that might have some anti-oxidant propertiesMedium~0.2–0.4%est.

Vitis vinifera fruit extractA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seedsMedium~0.2–0.4%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.2–0.4%est.

MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.25–0.45%est.

AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.2–0.35%est.

EthylhexylglycerinA preservativeMedium~0.25–0.45%est.

Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.25–0.4%est.

Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.2–0.4%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Alcohol~7.4–9%

Irritant · high

Irritation risk: High

Works for

Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol

Niacinamide~4.3–5.2%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Dipropylene glycol~2.8–3.4%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Hydroxyacetophenone~2.2–2.7%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Polysorbate 80~1.8–2.2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Polysorbate 80

Caprylyl glycol~1.6–1.9%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Pvp~1.3–1.6%

Irritant · medium

Irritation risk: Medium

Helps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin

More about Pvp

Adenosine~1–1.2%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Disodium edta~0.5–1%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Parfum~0.5–0.8%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Panthenol~0.5–0.7%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Butylene glycol~0.45–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Propanediol~0.4–0.6%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Myrothamnus flabellifolia callus culture extract~0.3–0.6%

Formula

Irritation risk: Low

More about Myrothamnus flabellifolia callus culture extract

Salix alba bark extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-oxidationAnti-inflammatoryAnti-blemishExfoliation

A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect

More about Salix alba bark extract

Lactobacillus/soybean ferment extract~0.3–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking

More about Lactobacillus/soybean ferment extract

Portulaca oleracea extract~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizing

A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin

More about Portulaca oleracea extract

Origanum vulgare leaf extract~0.25–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract. Can have an anti-oxidant effect, but can also contain irritants

More about Origanum vulgare leaf extract

Cinnamomum cassia bark extract~0.25–0.45%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Cinnamomum cassia bark extract

Scutellaria baicalensis root extract~0.15–0.3%

Irritant · high

Irritation risk: High

Works for

AntibacterialAnti-oxidationMoisturizingReduces irritationAnti-inflammatory

A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties

More about Scutellaria baicalensis root extract

Chamaecyparis obtusa leaf extract~0.2–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Chamaecyparis obtusa leaf extract

Pentylene glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Glycerin~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Dipotassium glycyrrhizate~0.2–0.35%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

1,2-hexanediol~0.2–0.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Camellia japonica flower extract~0.25–0.45%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin

More about Camellia japonica flower extract

Allium sativum bulb extract~0.2–0.4%

Formula

Irritation risk: Low

More about Allium sativum bulb extract

Brassica oleracea italica extract~0.25–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Might have some anti-inflammatory properties but research is lacking

More about Brassica oleracea italica extract

Vaccinium angustifolium fruit extract~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking

More about Vaccinium angustifolium fruit extract

Spinacia oleracea leaf extract~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Spinacia oleracea leaf extract

Salicornia herbacea extract~0.2–0.4%

Formula

Irritation risk: Low

More about Salicornia herbacea extract

Vitis vinifera fruit extract~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds

More about Vitis vinifera fruit extract

Juglans regia seed extract~0.2–0.4%

Formula

Irritation risk: Low

More about Juglans regia seed extract

Camellia sinensis leaf extract~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Solanum lycopersicum fruit extract~0.25–0.45%

Formula

Irritation risk: Low

More about Solanum lycopersicum fruit extract

Avena sativa meal extract~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of oatmeal extract. Helps restore skin barrier and has antioxidant properties

More about Avena sativa meal extract

Sodium hyaluronate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Leontopodium alpinum callus culture extract~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-inflammatory

A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin

More about Leontopodium alpinum callus culture extract

Sodium hyaluronate crosspolymer~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Madecassoside~0.25–0.45%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside

Sodium acetylated hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Asiaticoside~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside

Hydrolyzed sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Ethylhexylglycerin~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Hydrogenated polyisobutene~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Madecassic acid~0.25–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid

Asiatic acid~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingReduces irritationAnti-inflammatory

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid

Acetyl hexapeptide-8~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Copper tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Palmitoyl pentapeptide-4~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Anemarrhena asphodeloides root extract~0.15–0.3%

Formula

Irritation risk: Low

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Anemarrhena asphodeloides root extract

Tocopherol~0.15–0.3%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Butylphenyl methylpropional~0.1–0.15%

Irritant · high

Irritation risk: High

A fragrance. Can trigger allergic reactions and be irritating

More about Butylphenyl methylpropional

Hexyl cinnamal~0.1–0.15%

Irritant · high

Irritation risk: High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal

Ingredient list view

Water, Alcohol, Niacinamide, Dipropylene glycol, Hydroxyacetophenone, Polysorbate 80, Caprylyl glycol, Pvp, Adenosine, Disodium edta, Parfum, Panthenol, Butylene glycol, Propanediol, Myrothamnus flabellifolia callus culture extract, Salix alba bark extract, Lactobacillus/soybean ferment extract, Portulaca oleracea extract, Origanum vulgare leaf extract, Cinnamomum cassia bark extract, Scutellaria baicalensis root extract, Chamaecyparis obtusa leaf extract, Pentylene glycol, Glycerin, Dipotassium glycyrrhizate, 1,2-hexanediol, Camellia japonica flower extract, Allium sativum bulb extract, Brassica oleracea italica extract, Vaccinium angustifolium fruit extract, Spinacia oleracea leaf extract, Salicornia herbacea extract, Vitis vinifera fruit extract, Juglans regia seed extract, Camellia sinensis leaf extract, Solanum lycopersicum fruit extract, Avena sativa meal extract, Sodium hyaluronate, Leontopodium alpinum callus culture extract, Sodium hyaluronate crosspolymer, Madecassoside, Sodium acetylated hyaluronate, Asiaticoside, Hydrolyzed sodium hyaluronate, Ethylhexylglycerin, Hydrogenated polyisobutene, Madecassic acid, Asiatic acid, Acetyl hexapeptide-8, Copper tripeptide-1, Palmitoyl pentapeptide-4, Anemarrhena asphodeloides root extract, Tocopherol, Butylphenyl methylpropional, Hexyl cinnamal

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	KloreStem cell PSEYOUR PRODUCT	Farm StayBlack Snail & Peptide9 Perfect Serum	VT CosmeticsPDRN Reedle Shot 100	Carenology 95RE:BLUE Deep Concentrate Ampoule
Match	—	89%	85%	83%
Price	—	$20.50	$17.74	$13.50
Shared key ingredients	—	14 of 19	14 of 19	11 of 19
Key difference	—	Oligopeptide-32	Hexapeptide-9	Ceramide Np
Irritancy	High	Medium	Medium	Medium
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Klore - Stem cell PSE" is effective for: Moisturizing, Anti-blemish, Anti-aging and Evens skin tone

Ingredient callouts

A good concentration of Niacinamide (4.30% - 5.20%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
Peptides (palmitoyl pentapeptide-4 0.15% - 0.30%, copper tripeptide-1 0.20% - 0.35% and acetyl hexapeptide-8 0.20% - 0.40%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Adenosine 1.00% - 1.20%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.20% - 0.40%, madecassic acid 0.25% - 0.40%, asiaticoside 0.20% - 0.35% and madecassoside 0.25% - 0.45% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
Humectants (acetyl hexapeptide-8 0.20% - 0.40%, sodium acetylated hyaluronate 0.25% - 0.45%, sodium hyaluronate crosspolymer 0.20% - 0.40%, sodium hyaluronate 0.20% - 0.40%, glycerin 0.25% - 0.40% and panthenol 0.50% - 0.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 40 studies and safety reviews.

1
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
2
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
3
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
4
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
5
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
6
Efficacy and Safety of White Willow Bark (Salix alba) Extractonlinelibrary.wiley.com
7
An evaluation of the effect of a topical product containing salicin on the visible signs of human skin agingncbi.nlm.nih.gov
8
Portulaca oleracea (purslane)mdedge.com
9
Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plantsncbi.nlm.nih.gov
10
Flavonoids in Treating Psoriasissciencedirect.com
11
Improvement of skin barrier dysfunction by Scutellaria baicalensis GEOGI extracts through lactic acid fermentationonlinelibrary.wiley.com
12
Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmeticscir-safety.org
13
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
14
Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent modelresearchgate.net
15
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.ncbi.nlm.nih.gov
16
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
17
Anti-Inflammatory and Neuroactive Properties of Selected Fruit Extractsliebertpub.com
18
Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmeticscir-safety.org
19
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
20
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
21
Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cellshindawi.com
22
Centella asiatica in Dermatology: An Overviewonlinelibrary.wiley.com
23
Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytesncbi.nlm.nih.gov
24
Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stressonlinelibrary.wiley.com
25
Madecassoside Inhibits Melanin Synthesis by Blocking Ultraviolet-Induced Inflammationmdpi.com
26
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
27
The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trialliebertpub.com
28
Stability Study of the Active Constituents in the Centella asiatica Extract Formulationstandfonline.com
29
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
30
Centella asiatica in cosmetologyncbi.nlm.nih.gov
31
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
32
Centella asiatica in Dermatology: An Overviewonlinelibrary.wiley.com
33
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
34
Centella asiatica in Dermatology: An Overviewonlinelibrary.wiley.com
35
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
36
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
37
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
38
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com
39
Vitamin E in dermatologyncbi.nlm.nih.gov
40
Vitamin E and Skin Healthlpi.oregonstate.edu

KloreStem cell PSE

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