ISDIN Ureadin MANOS Handcreme Protect

ISDIN Ureadin MANOS Handcreme Protect

Efficacy75/100IrritancyHigh
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Works for

1 of 2 advertised claims delivered

Moisturizing
Paraffinum liquidum, Urea + 12 more
Strong evidence
What the product description says
“Speichert Wasser und spendet bis zu 24 Stunden lang Feuchtigkeit nach nur einer Anwendung.”
Source: ISDIN

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sorbitol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, isopropyl myristate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum, urea

Persea gratissima oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and could be helpful in repairing its barrier function~0.45–1.05%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–1.3%
Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~3.8–5.6%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~4.9–7.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.35–0.85%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~1.4–2%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.1–1.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.4–3.7%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~1.6–2.4%
Cetearyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin~1.3–1.9%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.35–0.8%
Lactic acidUnder-dosedEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.1–0.5%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.8%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.4–0.9%
Anti-aging
Lactic acid
Limited evidence
What the product description says
“Die Formel der ISDIN Ureadin® Manos Handcreme Protect enthält Inhaltsstoffe mit feuchtigkeitsspendenden und pflegenden Eigenschaften, die zur Regeneration der Haut beitragen und die Zeichen der Hautalterung reduzieren.”
Source: ISDIN

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.1–0.5%

Can it cause trouble?

Irritancy
7 strong irritants: Parfum, Limonene + 5 more — patch-test recommended
High risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.4%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.3%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.05–0.25%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.05–0.25%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.05–0.2%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.15%est.
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.01–0.1%est.
Persea gratissima oilAn emollient that helps soften the skin and could be helpful in repairing its barrier functionMedium~0.45–1.05%est.
EthylhexylglycerinA preservativeMedium~0.15–0.7%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.1–0.5%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~4.9–7.4%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Isopropyl myristate~4.9–7.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Paraffinum liquidum~3.8–5.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Glyceryl stearate~2.4–3.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-40 stearate~2–3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Peg-40 stearate
Sorbitol~1.6–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Urea~1.4–2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Cetearyl ethylhexanoate~1.3–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin

More about Cetearyl ethylhexanoate
Cetyl alcohol~1.1–1.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Dimethicone~0.55–1.3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Persea gratissima oil~0.45–1.05%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and could be helpful in repairing its barrier function

More about Persea gratissima oil
Carbomer~0.35–0.85%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Glycerin~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Allantoin~0.2–0.8%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Palmitic acid~0.35–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Stearic acid~0.4–0.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Ethylhexylglycerin~0.15–0.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium hydroxide~0.15–0.5%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Lactic acid~0.1–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Parfum~0.1–0.4%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Glyceryl polyacrylate~0.1–0.45%
Formula
Irritation risk
Low

Helps to create a nice product texture and spread the product more easily on the skin

More about Glyceryl polyacrylate
Limonene~0.1–0.3%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Hexyl cinnamal~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Coumarin~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Citral~0.05–0.2%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Linalool~0.05–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Alpha-isomethyl ionone~0.01–0.1%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Ingredient list view

Water, Isopropyl myristate, Paraffinum liquidum, Glyceryl stearate, Peg-40 stearate, Sorbitol, Urea, Cetearyl ethylhexanoate, Cetyl alcohol, Phenoxyethanol, Dimethicone, Persea gratissima oil, Carbomer, Glycerin, Allantoin, Palmitic acid, Stearic acid, Ethylhexylglycerin, Sodium hydroxide, Lactic acid, Parfum, Glyceryl polyacrylate, Limonene, Hexyl cinnamal, Coumarin, Citral, Linalool, Alpha-isomethyl ionone

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ISDINUreadin MANOS Handcreme ProtectYOUR PRODUCTTina’s DresserMoisturizing Hand Cream - 4 TypesPalmersCocoa Butter Intensive Relief Hand CreamPretty skinDesign Your Beauty Crocodile Hand Cream
Match—62%61%61%
Price—$9.00$2.67$10.50
Shared key ingredients—5 of 74 of 74 of 7
Key difference—NiacinamidePetrolatumCaprylic/Capric Triglyceride
Irritancy High Medium Low Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 8 studies and safety reviews.

  1. 1
  2. 2
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  3. 3
  4. 4
  5. 5
  6. 6
ISDIN Ureadin MANOS Handcreme Protect
ISDINUreadin MANOS Handcreme Protect

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