ISANA

ISANA Q10 Anti-Wrinkle Day Cream

Name: ISANA - Q10 Anti-Wrinkle Day Cream
Brand: ISANA

Efficacy87/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Moisturizing

18 ingredients credited for this claim

Strong evidence

What the product description says

“Q10 Anti-Wrinkle Day Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~3.2–3.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2–2.5%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.7–1.05%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.4–0.65%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.45–0.65%

PantolactoneKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.1–0.15%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.4–0.65%

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.45–0.65%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.3–0.55%

Coco-caprylateKey active· EmollientEffect: MediumAn emollient that softens skin and creates a nice product texture~5.7–6.9%

Hydrogenated vegetable glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.6–0.9%

C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~1.7–2%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.4–2.9%

Cocoglycerides· EmollientEffect: LowHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin~1.5–1.8%

Hydrogenated palm glycerides· EmollientEffect: LowAn emollient that softens the skin~0.3–0.55%

Lactic acidUnder-dosedEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.1–0.2%

Macadamia integrifolia seed oilUnder-dosedEffect: MediumA plant oil that helps soften the upper layer of the skin~0.55–0.8%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%

Anti-aging

3 ingredients credited for this claim

Moderate evidence

What the product description says

“Q10 Anti-Wrinkle Day Cream”

From product name

This product contains ubiquinone. This ingredient help neutralize free radicals in skin. By doing so, they might be able to prevent early signs of aging (like fine lines and wrinkles), at least to some extent. These ingredients will not be able to "reverse" signs of aging.

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.45–0.65%

Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.1–0.2%

Anti-oxidation

Not advertised by the brand · 4 ingredients credited for this claim

Strong evidence

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Chlorella vulgaris extractEffect: LowA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.3–0.55%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.5–0.7%

Can it cause trouble?

Irritancy

5 strong irritants: Parfum, Benzyl salicylate + 3 more — patch-test recommended

High risk

We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

CocoglyceridesHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skinHigh~1.5–1.8%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.35%est.

Benzyl salicylateA fragrance. Is a likely irritantHigh~0.2–0.35%est.

Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.15–0.25%est.

LinaloolA fragrance. Can be irritatingHigh~0.1–0.2%est.

CitronellolA fragrance. Can be irritatingHigh~0.05–0.1%est.

Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~5.7–6.9%est.

Phenylbenzimidazole sulfonic acidEnsulizole. A UV filter that is effective against UVB rays. Does not protect against UVA light. It is photostable and can be used to help stabilize other sunscreen ingredients. It is water-soluble meaning that it can help create lighter sunscreen formulationsMedium~4.4–5.4%est.

Bis-ethylhexyloxyphenol methoxyphenyl triazineTinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Unfortunately, not approved by FDA (US) yet.Medium~1.6–2%est.

Ethylhexyl triazoneUvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yetMedium~1.4–1.8%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.7–1.05%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.5–0.7%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.3–0.55%est.

Maris salUsed to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentrationMedium~0.25–0.5%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.2–0.35%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.

Disodium edtaStabilizes the product formulationMedium~0.2–0.35%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.1–0.2%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.3–0.55%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.4–2.9%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.7–1.05%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Coco-caprylate~5.7–6.9%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate

Phenylbenzimidazole sulfonic acid~4.4–5.4%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Ensulizole. A UV filter that is effective against UVB rays. Does not protect against UVA light. It is photostable and can be used to help stabilize other sunscreen ingredients. It is water-soluble meaning that it can help create lighter sunscreen formulations

More about Phenylbenzimidazole sulfonic acid

Arginine~3.2–3.9%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Cetearyl alcohol~2.4–2.9%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Glycerin~2–2.5%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

C12-15 alkyl benzoate~1.7–2%

Key active

Irritation risk: Low

Works for

Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate

Cocoglycerides~1.5–1.8%

Irritant · high

Irritation risk: High

Works for

CleansingMoisturizing

Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin

More about Cocoglycerides

Bis-ethylhexyloxyphenol methoxyphenyl triazine~1.6–2%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Tinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Unfortunately, not approved by FDA (US) yet.

More about Bis-ethylhexyloxyphenol methoxyphenyl triazine

Ethylhexyl triazone~1.4–1.8%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Uvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yet

More about Ethylhexyl triazone

Glycine soja oil~0.7–1.05%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Hydrogenated vegetable glycerides~0.6–0.9%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

Help soften the upper layer of the skin

More about Hydrogenated vegetable glycerides

Macadamia integrifolia seed oil~0.55–0.8%

Under-dosed

Irritation risk: Low

Works for

Moisturizing

A plant oil that helps soften the upper layer of the skin

More about Macadamia integrifolia seed oil

Tocopheryl acetate~0.5–0.7%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Panthenol~0.45–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Ubiquinone~0.45–0.65%

Key active

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone

Tocopherol~0.45–0.65%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Helianthus annuus seed oil~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Squalane~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Chlorella vulgaris extract~0.3–0.55%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-inflammatoryAnti-oxidation

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Maris sal~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Exfoliation

Used to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentration

More about Maris sal

Olive oil decyl esters~0.25–0.5%

Formula

Irritation risk: Low

More about Olive oil decyl esters

Potassium cetyl phosphate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Phenoxyethanol~0.25–0.45%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Bentonite~0.25–0.45%

Formula

Irritation risk: Low

Works for

Anti-blemish

Helps stabilize the product formulation

More about Bentonite

Hydrogenated palm glycerides~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides

Parfum~0.2–0.35%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Carbomer~0.25–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Xanthan gum~0.25–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Benzyl salicylate~0.2–0.35%

Irritant · high

Irritation risk: High

A fragrance. Is a likely irritant

More about Benzyl salicylate

Ethylhexylglycerin~0.2–0.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Citric acid~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Disodium edta~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Hydrated silica~0.3–0.55%

Formula

Irritation risk: Low

Works for

Mattifying

More about Hydrated silica

Alpha-isomethyl ionone~0.15–0.25%

Irritant · high

Irritation risk: High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone

Linalool~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Lactic acid~0.1–0.2%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Pantolactone~0.1–0.15%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Pantolactone

Citronellol~0.05–0.1%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Citronellol

Ingredient list view

Water, Coco-caprylate, Phenylbenzimidazole sulfonic acid, Arginine, Cetearyl alcohol, Glycerin, C12-15 alkyl benzoate, Cocoglycerides, Bis-ethylhexyloxyphenol methoxyphenyl triazine, Ethylhexyl triazone, Glycine soja oil, Hydrogenated vegetable glycerides, Macadamia integrifolia seed oil, Tocopheryl acetate, Panthenol, Ubiquinone, Tocopherol, Helianthus annuus seed oil, Squalane, Chlorella vulgaris extract, Maris sal, Olive oil decyl esters, Potassium cetyl phosphate, Phenoxyethanol, Bentonite, Hydrogenated palm glycerides, Parfum, Carbomer, Xanthan gum, Benzyl salicylate, Ethylhexylglycerin, Citric acid, Disodium edta, Hydrated silica, Alpha-isomethyl ionone, Linalool, Lactic acid, Pantolactone, Citronellol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ISANAQ10 Anti-Wrinkle Day CreamYOUR PRODUCT	BABORSkinovage Complex C Cream	HickapBedtime Magic Repairing Night Cream	MedicubeDeep Vita C Capsule Cream
Match	—	60%	58%	58%
Price	$4.89	$59.99+$55.10	—	$22.50+$17.61
Shared key ingredients	—	6 of 13	7 of 13	7 of 13
Key difference	—	Retinyl Palmitate	Hydroxypinacolone Retinoate	Niacinamide
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"ISANA - Q10 Anti-Wrinkle Day Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Panthenol, arginine, glycerin and pantolactone in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Glycine soja oil, arginine, helianthus annuus seed oil, squalane and c12-15 alkyl benzoate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: lactic acid and vitamin e

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.