ISANA

ISANA Q10 Anti-Wrinkle Day Cream

Name: ISANA - Q10 Anti-Wrinkle Day Cream
Brand: ISANA

Efficacy87/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Palmitoyl tripeptide-5, Panthenol + 14 more

Works well

What the product description says

“Infused with Vitamin E and Panthenol , this cream works to soothe / calm environmental stress while providing intense hydration .”

Source: German Drugstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, pantolactone.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, glycine soja oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tripeptide-5, panthenol

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.5%

C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~5.6–6.8%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.8–4.7%

Hydrogenated vegetable glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~2.9–3.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2–2.5%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.45–0.65%

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.4–0.6%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.25–0.45%

PantolactoneKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.2–0.4%

Dicaprylyl carbonate· EmollientEffect: LowHelps products spread more easily and works as an emollient to soften skin~1.2–1.4%

Dibutyl adipate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~0.55–0.8%

Hydrogenated palm glycerides· EmollientEffect: LowAn emollient that softens the skin~0.25–0.45%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.6–0.95%

Macadamia integrifolia seed oilUnder-dosedA plant oil that helps soften the upper layer of the skin~0.45–0.65%

Anti-aging

Palmitoyl tripeptide-5, Ubiquinone + 1 more

May help

What the product description says

“Q10 Anti-Wrinkle Day Cream”

Source: German Drugstore

This product contains palmitoyl tripeptide-5. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.4–0.6%

Anti-oxidation

Side benefit · Ubiquinone, Tocopheryl acetate + 1 more

Works well

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.45%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Can it cause trouble?

Irritancy

5 strong irritants: Parfum, Benzyl salicylate + 3 more — patch-test recommended

High risk

We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.

Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.2%est.

Benzyl salicylateA fragrance. Is a likely irritantHigh~0.1–0.2%est.

LinaloolA fragrance. Can be irritatingHigh~0.1–0.2%est.

Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.1–0.15%est.

CitronellolA fragrance. Can be irritatingHigh~0.05–0.1%est.

Phenylbenzimidazole sulfonic acidEnsulizole. A UV filter that is effective against UVB rays. Does not protect against UVA light. It is photostable and can be used to help stabilize other sunscreen ingredients. It is water-soluble meaning that it can help create lighter sunscreen formulationsMedium~3.2–3.9%est.

Butyl methoxydibenzoylmethaneAvobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.Medium~2.1–2.5%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.95–1.15%est.

Bis-ethylhexyloxyphenol methoxyphenyl triazineTinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Approved by the US FDA in 2026 (listed as bemotrizinol on US labels).Medium~1.1–1.4%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.6–0.95%est.

Ethylhexyl triazoneUvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yetMedium~0.65–1%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.45–0.65%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.

EthylhexylglycerinA preservativeMedium~0.2–0.4%est.

Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.8–4.7%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.45–0.65%est.

Alternatives

Cheaper, or higher on efficacy

Mizon S-Venom Wrinkle Tox Cream

Higher efficacy · 100/10056% match

$17.58

Abib YesStyle Exclusive PDRN Volume Fill-it Booster Crème 2.5 Tube Mini 5pcs Bundle Set

Higher efficacy · 100/10056% match

$37.53

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

C12-15 alkyl benzoate~5.6–6.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate

Cetearyl alcohol~3.8–4.7%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Hydrogenated vegetable glycerides~2.9–3.5%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

Help soften the upper layer of the skin

More about Hydrogenated vegetable glycerides

Phenylbenzimidazole sulfonic acid~3.2–3.9%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Ensulizole. A UV filter that is effective against UVB rays. Does not protect against UVA light. It is photostable and can be used to help stabilize other sunscreen ingredients. It is water-soluble meaning that it can help create lighter sunscreen formulations

More about Phenylbenzimidazole sulfonic acid

Glycerin~2–2.5%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Butyl methoxydibenzoylmethane~2.1–2.5%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Avobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.

More about Butyl methoxydibenzoylmethane

Cellulose~1.5–1.8%

Formula

Irritation risk: Low

Works for

Mattifying

Can be used to help absorb oil as well as add volume and imporve texture of products.

More about Cellulose

Dicaprylyl carbonate~1.2–1.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps products spread more easily and works as an emollient to soften skin

More about Dicaprylyl carbonate

Potassium cetyl phosphate~0.95–1.15%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Bis-ethylhexyloxyphenol methoxyphenyl triazine~1.1–1.4%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Tinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Approved by the US FDA in 2026 (listed as bemotrizinol on US labels).

More about Bis-ethylhexyloxyphenol methoxyphenyl triazine

Caprylic/capric triglyceride~0.6–0.95%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Dibutyl adipate~0.55–0.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Dibutyl adipate

Ethylhexyl triazone~0.65–1%

Irritant · medium

Irritation risk: Medium

Works for

Sun protection

Uvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yet

More about Ethylhexyl triazone

Glycine soja oil~0.45–0.65%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Macadamia integrifolia seed oil~0.45–0.65%

Under-dosed

Irritation risk: Low

Works for

Moisturizing

A plant oil that helps soften the upper layer of the skin

More about Macadamia integrifolia seed oil

Ubiquinone~0.4–0.6%

Key active

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone

Palmitoyl tripeptide-5~0.3–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Panthenol~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Tocopherol~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Tocopheryl acetate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Ethylhexylglycerin~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Hydrogenated palm glycerides~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides

Helianthus annuus seed oil~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Parfum~0.15–0.3%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Xanthan gum~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Sodium hydroxide~0.2–0.4%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Disodium edta~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Pantolactone~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Pantolactone

Citric acid~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Phenoxyethanol~0.15–0.3%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Benzyl alcohol~0.1–0.2%

Irritant · high

Irritation risk: High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol

Benzyl salicylate~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Is a likely irritant

More about Benzyl salicylate

Linalool~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Alpha-isomethyl ionone~0.1–0.15%

Irritant · high

Irritation risk: High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone

Citronellol~0.05–0.1%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Citronellol

Anise alcohol~0.05–0.1%

Formula

Irritation risk: Low

More about Anise alcohol

Ingredient list view

Water, C12-15 alkyl benzoate, Cetearyl alcohol, Hydrogenated vegetable glycerides, Phenylbenzimidazole sulfonic acid, Glycerin, Butyl methoxydibenzoylmethane, Cellulose, Dicaprylyl carbonate, Potassium cetyl phosphate, Bis-ethylhexyloxyphenol methoxyphenyl triazine, Caprylic/capric triglyceride, Dibutyl adipate, Ethylhexyl triazone, Glycine soja oil, Macadamia integrifolia seed oil, Ubiquinone, Palmitoyl tripeptide-5, Panthenol, Tocopherol, Tocopheryl acetate, Ethylhexylglycerin, Hydrogenated palm glycerides, Helianthus annuus seed oil, Parfum, Xanthan gum, Sodium hydroxide, Disodium edta, Pantolactone, Citric acid, Phenoxyethanol, Benzyl alcohol, Benzyl salicylate, Linalool, Alpha-isomethyl ionone, Citronellol, Anise alcohol

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German Drugstore50 ml

$4.69

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ISANAQ10 Anti-Wrinkle Day CreamYOUR PRODUCT	Dr. Duve MedicalClarifying Face Cream	StriVectinMulti-Action Restorative Cream	MizonS-Venom Wrinkle Tox Cream
Match	—	57%	57%	56%
Price	$4.69	—	$60.23+$55.54	$17.58+$12.89
Shared key ingredients	—	5 of 13	5 of 13	5 of 13
Key difference	—	Niacinamide	Acetyl Tetrapeptide-2	Copper Tripeptide-1
Irritancy	High	Medium	Low	Medium
Drying alcohol	—	Contains drying alcohol	—	—
	View product	Shop	Shop	Shop

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Product summary

"ISANA - Q10 Anti-Wrinkle Day Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Panthenol, arginine, glycerin and pantolactone in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Glycine soja oil, arginine, helianthus annuus seed oil, squalane and c12-15 alkyl benzoate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: lactic acid and vitamin e

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.