ISANA Ceramide Cream

ISANA Ceramide Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
14 ingredients credited for this claim
Strong support
What the product description says
“Ceramide Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, lactobacillus ferment.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, panthenol

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.65%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.1–0.4%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.6–5.4%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~2.6–3.9%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.1–1.6%
Theobroma cacao seed butterKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect~1.2–1.9%
Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~0.4–0.95%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.7–2.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.15–0.55%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.1–0.35%
Brassica campestris seed oilKey activeEffect: MediumHelps soften the upper layer of the skin~0.5–1.15%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~4.5–6.7%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.4–0.9%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.1–3.1%
Evens skin tone
1 ingredient credited for this claim
Strong support
What the product description says
“This skin-soothing moisturizer has been carefully developed to soothe redness and irritation of the skin, sustainably strengthen the skin barrier and promote an even complexion.”
Source: German Drugstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.6–5.4%
Anti-blemish
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.6–5.4%
Rosmarinus officinalis leaf extractUnder-dosedEffect: MediumCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.01–0.1%
Anti-aging
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.6–5.4%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~4.5–6.7%

Can it cause trouble?

Irritancy
2 strong irritants: Rosmarinus officinalis leaf extract, Alcohol
Medium risk
We flagged 6 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.01–0.1%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.01–0.05%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.1–3.1%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.4–0.95%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.65%est.
Potassium sorbateA preservativeMedium~0.1–0.45%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Theobroma cacao seed butterHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect3/5~1.2–1.9%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.15–0.55%est.
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Ingredients

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Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Prunus amygdalus dulcis oil~4.5–6.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Niacinamide~3.6–5.4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Panthenol~2.6–3.9%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Pentylene glycol~2.1–3.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Glycerin~1.7–2.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Stearyl alcohol~1.4–2.1%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Theobroma cacao seed butter~1.2–1.9%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-dandruff

Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect

More about Theobroma cacao seed butter
Squalane~1.1–1.6%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Polyglyceryl-3 stearate~0.8–1.25%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polyglyceryl-3 stearate
Brassica campestris seed oil~0.5–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Brassica campestris seed oil
Lactobacillus ferment~0.4–0.95%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatoryReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Potassium cetyl phosphate~0.4–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Glyceryl stearate citrate~0.4–0.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Xanthan gum~0.3–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Citric acid~0.15–0.65%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ceramide np~0.15–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Potassium sorbate~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Cetearyl alcohol~0.15–0.55%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Helianthus annuus seed oil~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Polygonum tinctorium leaf extract~0.1–0.3%
Formula
Cetyl alcohol~0.1–0.35%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Dipotassium phosphate~0.05–0.15%
Formula
Irritation risk
Low

Used to adjust the pH of the product

More about Dipotassium phosphate
Rosmarinus officinalis leaf extract~0.01–0.1%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAntibacterialAnti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Alcohol~0.01–0.05%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Ingredient list view

Water, Prunus amygdalus dulcis oil, Niacinamide, Panthenol, Pentylene glycol, Glycerin, Stearyl alcohol, Theobroma cacao seed butter, Squalane, Polyglyceryl-3 stearate, Brassica campestris seed oil, Lactobacillus ferment, Potassium cetyl phosphate, Glyceryl stearate citrate, Xanthan gum, Sodium benzoate, Citric acid, Ceramide np, Potassium sorbate, Cetearyl alcohol, Helianthus annuus seed oil, Polygonum tinctorium leaf extract, Cetyl alcohol, Dipotassium phosphate, Rosmarinus officinalis leaf extract, Alcohol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ISANACeramide CreamYOUR PRODUCTRilastilAcnestil Attiva CreambotikCica Pantenol + Niacinamida creamCOSNORIPanthenol Barrier Cream
Match—92%92%91%
Price—$24.44—$16.74
Shared key ingredients—5 of 84 of 85 of 8
Key difference—Potassium Azeloyl DiglycinateCeramide EopMadecassoside
Irritancy Medium Low Low Low
Drying alcohol Contains drying alcohol ———
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Product summary

"ISANA - Ceramide Cream" has a good moisturizing formula. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Panthenol, glycerin and lactobacillus ferment in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, theobroma cacao seed butter, helianthus annuus seed oil, squalane and cetearyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We love that this moisturizer contains a good concentration of niacinamide 3.60% - 5.40%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
  • As a plus, this moisturizer also contains Ceramides (ceramide np 0.15% - 0.65%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Panthenol (pro-vitamin B5) at about 2.60% - 3.90% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

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