Works for:
based on ingredients and %- Moisturizing
- Evens skin tone
- Anti-aging
- Anti-oxidation
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"iS Clinical - Super Serum Advance Plus" is effective for: Anti-inflammatory, Moisturizing, Evens skin tone and Anti-aging
Ingredient callouts
- This product also contains Vitamin C (Ascorbic Acid) 7.20% (declared) It can be helpful in stimulating collagen production, neutralizing free radicals in skin and improving pigmentation marks. We recommend to use up this product quickly after opening: Ascorbic Acid degrades fast when it gets in contact with air and light. The moment the product turns orange, it is a sign that a significant share of the vitamin C in it is no longer effective.
- Peptides (tripeptide-1 1.30% - 1.90%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiaticoside 0.20% - 0.75% and asiatic acid 0.15% - 0.55% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
- Humectants (urea 2.30% - 3.40%, hyaluronic acid 4.20% - 6.30% and glycerin 0.10% - 0.35%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 158.00$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
This super serum combines a 15 percent concentration of Vitamin C with Copper Tripeptide Growth Factors for enhanced anti-aging properties.
Source: Skinstore
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains ascorbic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Anti-oxidation
This product contains antioxidants (ascorbic acid, asiaticoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - arbutin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin
Evens skin tone
What does the product description say?
Safely and effectively treats hyperpigmentation. Helps to lighten scars. Provides UV photo-protection.
Source: Skinstore
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: ascorbic acid.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: arbutin.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin
Moisturizing
What does the product description say?
Recommended for all skin types except very dry and hyper-sensitive.
Source: Skinstore
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: tripeptide-1, pentylene glycol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: tripeptide-1, urea
Helps support skin barrier function improving skin hydration and reducing sensitivity
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
Used to preserve products, dissolve other ingredients and create a nice product texture
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 iS Clinical Super Serum Advance Plus | Current | $158.00 | |
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Reform Skincare Vitamin C 20% Serum | 69% | - | |
Biovene VITAMIN C 27% SERUM | 69% | $65.10 | |
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Key Actives
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin
Helps support skin barrier function improving skin hydration and reducing sensitivity
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Potential irritants
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Used to preserve products, dissolve other ingredients and create a nice product texture
Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Used to preserve products, dissolve other ingredients and create a nice product texture
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin
Helps support skin barrier function improving skin hydration and reducing sensitivity
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A preservative. It helps prevent bacterial growth in cosmetic products
Ingredient list view
Water, Ascorbic acid, Hyaluronic acid, Pentylene glycol, Urea, Glucose, Guanine, Tripeptide-1, Arbutin, Polyporus umbellatus extract, Calcium pantothenate, Asiaticoside, Asiatic acid, Zinc sulfate, Glycerin, Phenoxyethanol
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Topical urea in skincare: A review
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Arbutin - Commentaty
- TOPICAL TREATMENT OF MELASMA
- Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts
- Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivo
- Dexapanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation
- Centella asiatica in cosmetology
- Contact dermatitis due to Madecassol
- Centella asiatica in Dermatology: An Overview
- Contact dermatitis due to Madecassol
- Centella asiatica in Dermatology: An Overview
- Safety Assessment of Zinc Salts as Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions