Works for
Anti-agingAscorbic acidWorks well
“The appearance of fine lines and wrinkles are visibly reduced and skin tone is left looking more even and refined.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains ascorbic acid.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Evens skin toneAscorbic acidWorks well
“The appearance of fine lines and wrinkles are visibly reduced and skin tone is left looking more even and refined.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: ascorbic acid.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
MoisturizingSodium hyaluronate, Propylene glycolWorks
“Nourish lacklustre and ageing skin with the i S Clinical C-15 Serum Advance+ ; a water-based serum that expertly blends natural plant-based extracts with scientific active ingredients to infuse skin with hydration and vitamins.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": sodium hyaluronate, propylene glycol.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
Anti-oxidationSide benefit · Ascorbic acidWorks well
This product contains antioxidants (ascorbic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy3 flagged ingredientsLow risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
Be the first — your take helps the next person decide.
Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Sodium hyaluronate~8.1–12.2%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateAscorbic acid~4.8–7.2%
- Irritation risk
- High
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
More about Ascorbic acidPropylene glycol~2.6–3.9%
- Irritation risk
- High
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
More about Propylene glycolZinc sulfate~1.1–1.6%
Bioflavonoids~0.8–1.25%
- Irritation risk
- Low
Phenoxyethanol~0.5–1%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIngredient list view
Water, Sodium hyaluronate, Ascorbic acid, Propylene glycol, Zinc sulfate, Bioflavonoids, Phenoxyethanol
Compare prices
Retailers ranked by price — lowest first.
Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.
Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| iS ClinicalC-15 Serum Advance PlusYOUR PRODUCT | SkinCeuticalsSerum 20 AOX | Cellex-CHigh Potency Serum | NourishMaxVITAMIN C + B + E + FERULIC & RETINOL SERUM | |
|---|---|---|---|---|
| Match | — | 100% | 99% | 98% |
| Price | $177.00 | $128.00−$49.00 | $116.57−$60.43 | $59.00−$118.00 |
| Shared key ingredients | — | 2 of 2 | 2 of 2 | 2 of 2 |
| Key difference | — | Ferulic Acid | Camellia Sinensis Leaf Extract | Ferulic Acid |
| Irritancy | Low | Low | Low | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: NuFace Lifter Vitamin C and Hyaluronic Acid Serum S3Paula's choice Active Serum Intensive Vitamin C and E + Ferulic Acid
Product summary
"iS Clinical - C-15 Serum Advance Plus" is effective for: Anti-aging and Evens skin tone
This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- This product also contains Vitamin C (Ascorbic Acid) 4.80% - 7.20% It can be helpful in stimulating collagen production, neutralizing free radicals in skin and improving pigmentation marks. We recommend to use up this product quickly after opening: Ascorbic Acid degrades fast when it gets in contact with air and light. The moment the product turns orange, it is a sign that a significant share of the vitamin C in it is no longer effective.
- Humectants (sodium hyaluronate 8.10% - 12.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 52.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.
- 1Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 2
- 3Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
- 4Propylene Glycolpubmed.ncbi.nlm.nih.gov
- 5Skin-sensitizing and irritant properties of propylene glycolonlinelibrary.wiley.com
- 6Safety Assessment of Zinc Salts as Used in Cosmeticscir-safety.org
Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.