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Hada labo Unscented Hada Labo Tokyo Overnight Treatment Cream
Hada labo

Hada labo Unscented Hada Labo Tokyo Overnight Treatment Cream

Efficacy75/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Tetrapeptide-5, Glycine soja seed extract
May help
What the product description says
“Formulated to hydrate, repair and firm skin, this hydrating moisturizer contains Super Hyaluronic Acid (TM) for long-lasting moisture to restore and strengthen skin's natural hydrating levels, a soy peptide complex to help fortify skin's structure and reduce the appearance of fine lines and improve loss of elasticity, and collagen for improved texture and firmness.”
Source: Target

This product contains tetrapeptide-5. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Tetrapeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.35–0.75%
Moisturizing
Glycerin, Dimethicone + 14 more
Works
What the product description says
“Formulated to hydrate, repair and firm skin, this hydrating moisturizer contains Super Hyaluronic Acid (TM) for long-lasting moisture to restore and strengthen skin's natural hydrating levels, a soy peptide complex to help fortify skin's structure and reduce the appearance of fine lines and improve loss of elasticity, and collagen for improved texture and firmness.”
Source: Target

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed collagen.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–5.8%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.7–4.1%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.7–2.6%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~1.4–2.1%
TriethylhexanoinKey activeEffect: HighHelps soften the upper layer of the skin~1.1–1.6%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.55–1.25%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.35–0.85%
Glycine soja seed extractKey active· EmollientEffect: MediumAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.35–0.75%
Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.3–0.75%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.15–0.7%
Hydrolyzed soy proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.15–0.65%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.1–0.3%
Tetrapeptide-5Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.05–0.25%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.5–5.2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.1–3.1%
Evens skin tone
Side benefit · Pancratium maritimum extract, Glycine soja seed extract + 1 more
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycine soja seed extract, pancratium maritimum extract.

Pancratium maritimum extractKey activeEffect: MediumA plant extract that might help neutralize free radicals in skin. It might help reduce hyperpigmentation~0.1–0.5%
Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.35–0.75%
Hydrolyzed soy proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.15–0.65%

Can it cause trouble?

Irritancy
1 strong irritant: Alcohol
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.8–1.25%est.
Lonicera japonica flower extractA plant extract that might help neutralize free radicals in skin. Can contain volalite oils and be irritatingHigh~0.1–0.5%est.
Pancratium maritimum extractA plant extract that might help neutralize free radicals in skin. It might help reduce hyperpigmentationHigh~0.1–0.5%est.
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.1–0.45%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.1–3.1%est.
TriethylhexanoinHelps soften the upper layer of the skinMedium~1.1–1.6%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.55–1.25%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Disodium edtaStabilizes the product formulationMedium~0.3–0.7%est.
Glycine soja seed extractAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.Medium~0.35–0.75%est.
Laureth-4Helps water and oil mix togetherMedium~0.15–0.6%est.
Laureth-23Helps oil and water mix togetherMedium~0.2–0.7%est.
PvpHelps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skinMedium~0.1–0.35%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.05–0.15%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laureth-4Helps water and oil mix together2/5~0.15–0.6%est.
Laureth-23Helps oil and water mix together2/5~0.2–0.7%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.9–5.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~3.5–5.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dimethicone~2.7–4.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Pentylene glycol~2.1–3.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Squalane~1.7–2.6%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Trehalose~1.4–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Triethylhexanoin~1.1–1.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Triethylhexanoin
Ammonium acryloyldimethyltaurate/vp copolymer~1–1.5%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Alcohol~0.8–1.25%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Caprylic/capric triglyceride~0.55–1.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Dimethicone crosspolymer-3~0.35–0.8%
Formula
Irritation risk
Low
More about Dimethicone crosspolymer-3
Dimethiconol~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Disodium edta~0.3–0.7%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Glycine soja seed extract~0.35–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationReduces rednessEvens skin toneAnti-aging

An emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.

More about Glycine soja seed extract
Hydrolyzed collagen~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen
Hydrolyzed hyaluronic acid~0.15–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Hydrolyzed soy protein~0.15–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing

More about Hydrolyzed soy protein
Kjellmaniella crassifolia extract~0.15–0.7%
Formula
Irritation risk
Low
More about Kjellmaniella crassifolia extract
Laureth-4~0.15–0.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps water and oil mix together

More about Laureth-4
Laureth-23~0.2–0.7%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together

More about Laureth-23
Lonicera japonica flower extract~0.1–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals in skin. Can contain volalite oils and be irritating

More about Lonicera japonica flower extract
Pancratium maritimum extract~0.1–0.5%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-oxidation

A plant extract that might help neutralize free radicals in skin. It might help reduce hyperpigmentation

More about Pancratium maritimum extract
Peg-8 methyl ether triethoxysilane~0.1–0.5%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-8 methyl ether triethoxysilane
Phenoxyethanol~0.1–0.45%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Physalis angulata extract~0.1–0.45%
Formula
Irritation risk
Low
More about Physalis angulata extract
Pullulan~0.1–0.45%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Pvp~0.1–0.35%
Irritant · medium
Irritation risk
Medium

Helps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin

More about Pvp
Sodium acetylated hyaluronate~0.1–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Sodium hyaluronate~0.05–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Tetrapeptide-5~0.05–0.2%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tetrapeptide-5
Titanium dioxide~0.05–0.2%
Formula
Irritation risk
Low
Works for
Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide
Tocopheryl acetate~0.05–0.15%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ingredient list view

Water, Glycerin, Butylene glycol, Dimethicone, Pentylene glycol, Squalane, Trehalose, Triethylhexanoin, Ammonium acryloyldimethyltaurate/vp copolymer, Alcohol, Caprylic/capric triglyceride, Chlorphenesin, Dimethicone crosspolymer-3, Dimethiconol, Disodium edta, Glycine soja seed extract, Hydrolyzed collagen, Hydrolyzed hyaluronic acid, Hydrolyzed soy protein, Kjellmaniella crassifolia extract, Laureth-4, Laureth-23, Lonicera japonica flower extract, Pancratium maritimum extract, Peg-8 methyl ether triethoxysilane, Phenoxyethanol, Physalis angulata extract, Pullulan, Pvp, Sodium acetylated hyaluronate, Sodium hyaluronate, Tetrapeptide-5, Titanium dioxide, Tocopheryl acetate

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Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Hada laboUnscented Hada Labo Tokyo Overnight Treatment CreamYOUR PRODUCTPeter Thomas RothFirm X Collagen MoisturiserDr.Reju-AllAdvanced PDRN Rejuvenating Cream MaxNatureONEIntensive Neck Cream
Match—41%41%40%
Price—$61.60$62.56$23.70
Shared key ingredients—5 of 145 of 147 of 14
Key difference—Palmitoyl Tripeptide-5NiacinamideCopper Tripeptide-1
Irritancy Medium Low Low Low
Drying alcohol Contains drying alcohol ———
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Amended Safety Assessment of Triglycerides as Used in Cosmeticscir-safety.org
  5. 5
    Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
  6. 6
    Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
Hada labo Unscented Hada Labo Tokyo Overnight Treatment Cream
Hada laboUnscented Hada Labo Tokyo Overnight Treatment Cream
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