
“CoQ10, niacinamide, glucosamine, retinol and hyaluronic acid formula fights aging on a cellular level”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
“Dark spots caused by hyperpigmentation and signs of aging from the sun are diminished through regular use of this treatment, leaving the hands soft and smooth.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine, niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
“Skin is softened and moisturized with this fast-absorbing rich cream that combines the power of CoQ10, niacinamide, glucosamine and retinol with hyaluronic acid to nourish and repair the hands.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, saccharomyces/copper ferment.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, niacinamide
This product contains antioxidants (thioctic acid, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).


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A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideHelps oil and water mix together and works as an emollient
More about Stearic acidA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinAn emollient that helps soften the skin and could be helpful in repairing its barrier function
More about Persea gratissima oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.
More about Glycine soja oilIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolYeast extract that contains copper. Can help to attract water to the upper layer of the skin and can help in skin wound healing
More about Saccharomyces/copper fermentAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
More about Acetyl glucosamineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
More about CaffeineThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
More about Retinyl palmitateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
More about Sodium ascorbyl phosphateA great emollient that can also have anti-oxidant properties
More about Vitis vinifera seed oilCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
More about UbiquinoneA preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products
More about Glyceryl caprylateCan work as an exfoliant but is typically used to adjust the product pH
More about Citric acidWater, Caprylic/capric triglyceride, Stearic acid, Octyldodecyl stearoyl stearate, Cetearyl alcohol, Glyceryl stearate, Squalane, Glycerin, Persea gratissima oil, Glycine soja oil, Niacinamide, Sodium hyaluronate, Acetyl hexapeptide-8, Tocopherol, Dimethyl mea, Thioctic acid, Saccharomyces/copper ferment, Acetyl glucosamine, Carnitine, Caffeine, Ruscus aculeatus root extract, Sodium benzoate, Retinyl palmitate, Sodium ascorbyl phosphate, Citrus paradisi peel oil, Vitis vinifera seed oil, Ubiquinone, Phenoxyethanol, Ethylhexylglycerin, Aspalathus linearis extract, Sodium hydroxide, Glyceryl caprylate, Citric acid, Potassium sorbate
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Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Goldfaden MDHands To Heart by Goldfaden MdYOUR PRODUCT | skintificRetinol Skin Renewal Moisturizer Acne & Anti-Aging Night Cream | NécessaireThe Hand Cream - With Peptide | BiopelleEmepelle Night Cream | |
|---|---|---|---|---|
| Match | — | 76% | 75% | 74% |
| Price | $37.45 | $14.90−$22.55 | $27.00−$10.45 | — |
| Shared key ingredients | — | 8 of 17 | 5 of 17 | 7 of 17 |
| Key difference | — | Retinol | Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine | Fructose |
| Irritancy | Medium | Medium | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Fenty Skin Thicc N Smooth Rich Peptide Eye CreamNEOGEN X SUR.MEDIC Surmedic 24K Gold Caviar Repair Vital Cream
"Goldfaden MD - Hands To Heart by Goldfaden Md" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Acetyl glucosamine, acetyl hexapeptide-8, glycerin, saccharomyces/copper ferment and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Glycine soja oil, persea gratissima oil, vitis vinifera seed oil, caprylic/capric triglyceride and squalane in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
The product retails for 38.00$ in the United States and for 35.00£ in the United Kingdom.
For a detailed price comparison: click here.
Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.
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