GLOXINIALIFE by DR. CALLE Clear Defense SPF 45- Oil-Free Facial Sunscreen for Acne Prone Skin with Zinc Oxide- Daily Botanical Cream for Face Use- Anti Aging with UV Skin Protection
Works for:
based on ingredients and %- Sun protection
- Evens skin tone
- Moisturizing
- Anti-aging
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredient list, we assess that "GLOXINIALIFE by DR. CALLE - Clear Defense SPF 45- Oil-Free Facial Sunscreen for Acne Prone Skin with Zinc Oxide- Daily Botanical Cream for Face Use- Anti Aging with UV Skin Protection" can provide reliable sun protection. It can protect from both UVA and UVB rays. This is great news because not all sunscreens with SPF ratings give UVA protection. (UVA rays do not cause sunburn, but still damage our skin and lead to early aging).
Because it includes good moisturizing ingredients, it can also work as a hydrating day cream. Like all broad-spectrum sunscreens, this product helps prevent early signs of aging.
Sunscreen filters
This sunscreen uses a mixture of both mineral and organic (so-called "chemical") UV filters. Here are the organic filters this product uses: octinoxate. As for the mineral filters, this sunscreen uses zinc oxide.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
What does the product description say?
Anti Aging with UV Skin Protection
Source: From product name
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
This product can also help prevent early signs of skin aging because it offers a good level of broad spectrum sun protection. Sun damage is the main cause of premature skin aging, and protecting your skin from the sun is the best anti-aging strategy.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Anti-oxidation
This product contains antioxidants (polygonum aviculare extract, tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Evens skin tone
What does the product description say?
PROFESSIONAL, MEDICAL GRADE GLOXINIALIFE ® BY DR. CALLE ® CLEAR DEFENSE SPF 45; dermatologist-recommended, offers broad-spectrum UVA/UVB protection; It contains hyaluronic acid and niacinamide providing skin hydration and correction of uneven skin tone CALMS AND PROTECTS ACNE PRONE SKIN; oil-free sunscreen; reduces redness, blotchiness, and hyperpigmentation.
Source: Walmart
This product offers broad spectrum sun protection. It means that it can prevent hyperpigmentation and help keep the skin tone even (sun damage is the main factor causing age spots, darkening of post-acne marks and other discolorations).
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
What does the product description say?
PROFESSIONAL, MEDICAL GRADE GLOXINIALIFE ® BY DR. CALLE ® CLEAR DEFENSE SPF 45; dermatologist-recommended, offers broad-spectrum UVA/UVB protection; It contains hyaluronic acid and niacinamide providing skin hydration and correction of uneven skin tone CALMS AND PROTECTS ACNE PRONE SKIN; oil-free sunscreen; reduces redness, blotchiness, and hyperpigmentation.
Source: Walmart
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: octyldodecyl neopentanoate, cyclopentasiloxane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An emollient that helps soften the skin. Often used to stabilize other ingredients, for example, sunscreen
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Sun protection
This product offers a good level of protection against both UVB and UVA rays.
This sunscreen uses organic (so-called "chemical") sunscreen filters. Organic, or "chemical" filters usually provide reliable sun protection and rarely leave a white cast. Sunscreens with organic filters can sting eyes.
A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant
Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating
Anti-blemish
This product might be able to help reduce blemishes and clogged pores because it contains niacinamide.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Sun protection | |
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 90/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 GLOXINIALIFE by DR. CALLE Clear Defense SPF 45- Oil-Free Facial Sunscreen for Acne Prone Skin with Zinc Oxide- Daily Botanical Cream for Face Use- Anti Aging with UV Skin Protection | Current | - | |
 SkinMedica Essential Defense Everyday Clear Broad Spectrum SPF 47 | 96% | $40.00 | |
 DRMTLGY Daily Anti Aging Facial Moisturizer with Clear Broad Spectrum Sunscreen SPF 45 | 92% | - | |
 NassifMD Dermaceuticals Defend and Soothe Daily Antioxidant Sunscreen SPF46 | 92% | $40.00 | |
Replenix Hydrating Oil-Free Face Sunscreen SPF50+ | 82% | $32.00 | |
 SOBEL SKIN Rx Mineral-Based SPF 50 Sunscreen | 78% | $48.00 |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An emollient that helps soften the skin. Often used to stabilize other ingredients, for example, sunscreen
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant
Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An emollient that helps soften the skin. Often used to stabilize other ingredients, for example, sunscreen
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
Can work as an exfoliant but is typically used to adjust the product pH
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
Can work as an exfoliant but is typically used to adjust the product pH
Comedogenic ingredients
All ingredients
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
An emollient that helps soften the skin. Often used to stabilize other ingredients, for example, sunscreen
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Can work as an exfoliant but is typically used to adjust the product pH
A preservative. It helps prevent bacterial growth in cosmetic products
A type of silicone that helps oil and water mix well together. Helps to disperse other ingredients, e.g. pigments, evenly in a formulation
A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant
Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
An emollient that helps soften the skin. Often used to stabilize other ingredients, for example, sunscreen
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Can work as an exfoliant but is typically used to adjust the product pH
A preservative. It helps prevent bacterial growth in cosmetic products
A type of silicone that helps oil and water mix well together. Helps to disperse other ingredients, e.g. pigments, evenly in a formulation
Ingredient list view
Niacinamide, Tocopherol, Tocopheryl acetate, Rosa damascena extract, Hyaluronic acid, Sodium hyaluronate, Water, Cyclopentasiloxane, Oleth-3 phosphate, Octyldodecyl neopentanoate, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Polyisobutene, Peg-7 trimethylolpropane coconut ether, Glycerin, Tocopheryl acetate, Polygonum aviculare extract, Sodium hyaluronate, Disodium edta, Sodium hydroxide, Citric acid, Phenoxyethanol, Ethylhexylglycerin, Polyglyceryl-3 polydimethylsiloxyethyl dimethicone, Triethoxysilylethyl polydimethylsiloxyethyl hexyl dimethicone, Triethoxycaprylylsilane, Zinc oxide, Ethylhexyl methoxycinnamate, Niacinamide, Tocopherol, Tocopheryl acetate, Rosa damascena extract, Hyaluronic acid, Sodium hyaluronate, Water, Cyclopentasiloxane, Oleth-3 phosphate, Octyldodecyl neopentanoate, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Polyisobutene, Peg-7 trimethylolpropane coconut ether, Glycerin, Tocopheryl acetate, Polygonum aviculare extract, Sodium hyaluronate, Disodium edta, Sodium hydroxide, Citric acid, Phenoxyethanol, Ethylhexylglycerin, Polyglyceryl-3 polydimethylsiloxyethyl dimethicone, Triethoxysilylethyl polydimethylsiloxyethyl hexyl dimethicone, Triethoxycaprylylsilane
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
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- Glycerol and the skin: holistic approach to its origin and functions
- Juglanin ameliorates UVB-induced skin carcinogenesis via anti-inflammatory and proapoptotic effects in vivo and in vitro
- A review of inorganic UV filters zinc oxide and titanium dioxide
- Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens
- Characterization of the UVA protection provided by avobenzone, zinc oxide, and titanium dioxide in broad-spectrum sunscreen products
- Ultraviolet Protection Properties of Commercial Sunscreens and Sunscreens Containing Zno Nanorods
- ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells