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Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer Cream
Estée Lauder

Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Trifluoroacetyl tripeptide-2, Acetyl glucosamine + 33 more
Strong evidence
What the product description says
“Resilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer Cream”
Source: Sephora CA

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, artemia extract.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, algae extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, linoleic acid, petrolatum, trifluoroacetyl tripeptide-2

Thermus thermophillus fermentKey active· HumectantEffect: HighMight be helpful in neutralising free radicals in skin and have some hydration properties~0.2–0.35%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.15–0.3%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.2–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.2–0.35%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.15–0.3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.9–2.4%
Trifluoroacetyl tripeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.3%
Persea gratissima oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and could be helpful in repairing its barrier function~0.3–0.55%
Zinc pcaKey active· HumectantEffect: HighA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.15–0.25%
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetateKey activeEffect: HighA peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid~0.15–0.3%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.15–0.25%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.25–0.45%
Artemia extractKey active· HumectantEffect: HighZooplankton extract that can attract water to the upper level of the skin and might have some anti-oxidant effect~0.15–0.25%
PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~4.3–5.2%
Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.3–0.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.2–1.4%
Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.2–0.4%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.15–0.3%
Whey protein· EmollientEffect: LowA protein derived from milk. In skincare products, might help to soften the upper layer of the skin~0.25–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.2–2.7%
Caprylic/capric/myristic/stearic triglyceride· EmollientEffect: LowHelps to soften the upper layer of the skin~4.8–5.9%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.8–1.2%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.25–0.45%
Propylene glycol dicaprylate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product texture~0.2–0.4%
Hexyldecyl stearate· EmollientEffect: LowHelps create a nice product feeling on the skin and help soften its upper layer~3.1–3.8%
Myristyl alcohol· EmollientEffect: LowHelps to stabilize the product formulation while softening the upper layer of the skin. Can be irritating~0.2–0.35%
Myristyl myristateUnder-dosedEffect: HighAn emollient. Is not recommended for acne-prone skin as it can be comedogenic~0.15–0.3%
Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.25–0.4%
Yeast extractUnder-dosedEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.15–0.3%
Laminaria digitata extractUnder-dosedEffect: MediumSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.3%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.35–0.6%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.3–0.55%
Anti-aging
Acetyl glucosamine, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate + 8 more
Strong evidence
What the product description says
“Lines and wrinkles appear significantly reduced for skin that’s smooth and healthy-looking.”
Source: Sephora CA

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, trifluoroacetyl tripeptide-2.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.15–0.25%
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetateKey activeEffect: MediumA peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid~0.15–0.3%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Trifluoroacetyl tripeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.15–0.25%
Thermus thermophillus fermentEffect: LowMight be helpful in neutralising free radicals in skin and have some hydration properties~0.2–0.35%
Decarboxy carnosine hclEffect: LowMight be able to protect the skin from free radicals, but further evidence of effectiveness is needed~0.15–0.25%
Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.25–0.45%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.3%
Evens skin tone
Not advertised by the brand · Acetyl glucosamine, Yeast extract + 2 more
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.15–0.25%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Yeast extractEffect: Low, below effective doseHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.15–0.3%
Narcissus tazetta bulb extractEffect: Low, below effective doseMight contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lacking~0.45–0.65%
Anti-oxidation
Not advertised by the brand · Decarboxy carnosine hcl, Thermus thermophillus ferment + 13 more
Moderate evidence

This product contains antioxidants (decarboxy carnosine hcl) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Decarboxy carnosine hclKey activeEffect: MediumMight be able to protect the skin from free radicals, but further evidence of effectiveness is needed~0.15–0.25%
Thermus thermophillus fermentEffect: LowMight be helpful in neutralising free radicals in skin and have some hydration properties~0.2–0.35%
Cucumis melo fruit extractEffect: LowA fruit extract that might have some anti-oxidant properties~0.25–0.45%
CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.2–0.4%
Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.15–0.25%
Artemia extractEffect: LowZooplankton extract that can attract water to the upper level of the skin and might have some anti-oxidant effect~0.15–0.25%
ErgothioneineUnder-dosedEffect: HighCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.15–0.3%
Aminopropyl ascorbyl phosphateUnder-dosedEffect: MediumA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)~0.15–0.3%
Yeast extractUnder-dosedEffect: MediumHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.15–0.3%
Polygonum cuspidatum root extractEffect: Low, below effective doseA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product~0.15–0.3%
Narcissus tazetta bulb extractEffect: Low, below effective doseMight contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lacking~0.45–0.65%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.3%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.35–0.6%
Hordeum vulgare extractEffect: Low, below effective doseA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten~0.3–0.55%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.2–0.35%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 26 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Myristyl alcoholHelps to stabilize the product formulation while softening the upper layer of the skin. Can be irritatingHigh~0.2–0.35%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.
Hexyldecyl stearateHelps create a nice product feeling on the skin and help soften its upper layerMedium~3.1–3.8%est.
Narcissus tazetta bulb extractMight contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lackingMedium~0.45–0.65%est.
Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.35–0.6%est.
Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.3–0.55%est.
Cucumis melo fruit extractA fruit extract that might have some anti-oxidant propertiesMedium~0.25–0.45%est.
Persea gratissima oilAn emollient that helps soften the skin and could be helpful in repairing its barrier functionMedium~0.3–0.55%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.2–0.4%est.
Thermus thermophillus fermentMight be helpful in neutralising free radicals in skin and have some hydration propertiesMedium~0.2–0.35%est.
Polygonum cuspidatum root extractA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the productMedium~0.15–0.3%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenicMedium~0.15–0.3%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.2–0.35%est.
Aminopropyl ascorbyl phosphateA more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)Medium~0.15–0.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.2–0.35%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.25–0.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.35%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.15–0.3%est.
Potassium sulfateUsed to create a thicker product consistencyMedium~0.2–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.
Potassium sorbateA preservativeMedium~0.15–0.3%est.
Disodium edtaStabilizes the product formulationMedium~0.15–0.3%est.
BhtA preservativeMedium~0.15–0.25%est.
Ci 42090A colorant (dye)Medium~0.15–0.25%est.
Ci 17200A red colorantMedium~0.1–0.15%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~0.25–0.45%est.
Laminaria digitata extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment3/5~0.15–0.3%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenic3/5~0.15–0.3%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.2–1.4%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric/myristic/stearic triglyceride~4.8–5.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin

More about Caprylic/capric/myristic/stearic triglyceride
Petrolatum~4.3–5.2%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Hexyldecyl stearate~3.1–3.8%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps create a nice product feeling on the skin and help soften its upper layer

More about Hexyldecyl stearate
Butylene glycol~2.2–2.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dimethicone~1.9–2.4%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glycereth-26~1.6–1.9%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Peg-100 stearate~1.4–1.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Cetearyl alcohol~1.2–1.4%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glyceryl stearate~0.8–1.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Propanediol~0.6–0.9%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Narcissus tazetta bulb extract~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

Might contain compounds called dormins that in theory could help lighten skin and reduce hyperpigmentation, but solid research is lacking

More about Narcissus tazetta bulb extract
Cucumis sativus fruit extract~0.35–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizing

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract
Mimosa tenuiflora bark extract~0.25–0.5%
Formula
Irritation risk
Low
More about Mimosa tenuiflora bark extract
Hordeum vulgare extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract
Cucumis melo fruit extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A fruit extract that might have some anti-oxidant properties

More about Cucumis melo fruit extract
Persea gratissima oil~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and could be helpful in repairing its barrier function

More about Persea gratissima oil
Whey protein~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

A protein derived from milk. In skincare products, might help to soften the upper layer of the skin

More about Whey protein
Caffeine~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Thermus thermophillus ferment~0.2–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-aging

Might be helpful in neutralising free radicals in skin and have some hydration properties

More about Thermus thermophillus ferment
Algae extract~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract
Laminaria digitata extract~0.15–0.3%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment

More about Laminaria digitata extract
Artemia extract~0.15–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Zooplankton extract that can attract water to the upper level of the skin and might have some anti-oxidant effect

More about Artemia extract
Acetyl hexapeptide-8~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Polygonum cuspidatum root extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product

More about Polygonum cuspidatum root extract
Ergothioneine~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Trifluoroacetyl tripeptide-2~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Trifluoroacetyl tripeptide-2
Trehalose~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Sorbitol~0.15–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Glycerin~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Decarboxy carnosine hcl~0.15–0.25%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

Might be able to protect the skin from free radicals, but further evidence of effectiveness is needed

More about Decarboxy carnosine hcl
Cholesterol~0.2–0.35%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Isohexadecane~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Acetyl glucosamine~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Myristyl myristate~0.15–0.3%
Under-dosedComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Is not recommended for acne-prone skin as it can be comedogenic

More about Myristyl myristate
Cetearyl glucoside~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate~0.15–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid

More about Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate
Propylene glycol dicaprylate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Propylene glycol dicaprylate
Aminopropyl ascorbyl phosphate~0.15–0.3%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingEvens skin toneAnti-oxidation

A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)

More about Aminopropyl ascorbyl phosphate
Caprylyl glycol~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Caprylic/capric triglyceride~0.25–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Tocopheryl acetate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Linoleic acid~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid
Polysorbate 80~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Yeast extract~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-oxidationReduces irritationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract
Propylene glycol dicaprate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate
Zinc pca~0.15–0.25%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishAnti-oxidationAnti-aging

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca
Helianthus annuus seedcake~0.25–0.5%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Helianthus annuus seedcake
Hexylene glycol~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.2–0.35%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Sodium hyaluronate~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Myristyl alcohol~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps to stabilize the product formulation while softening the upper layer of the skin. Can be irritating

More about Myristyl alcohol
Tromethamine~0.15–0.3%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Stearic acid~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Potassium sulfate~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Potassium sulfate
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.2–0.35%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Citric acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Maltodextrin~0.2–0.35%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Aluminum hydroxide~0.2–0.4%
Formula
Irritation risk
Low

Is used to add opaque (non-transparent) appearance to formulations. Can be used to coat other ingredients for even dispersion. This is a different ingredient compared to the ones used in antipersperants (aluminium chloride and aluminium chlorohydrate)

More about Aluminum hydroxide
Parfum~0.15–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Potassium sorbate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Dextran~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Disodium edta~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Bht~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Phenoxyethanol~0.15–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ci 42090~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Ci 17200~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Titanium dioxide~0.1–0.2%
Formula
Irritation risk
Low
Works for
Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide
Ingredient list view

Water, Caprylic/capric/myristic/stearic triglyceride, Petrolatum, Hexyldecyl stearate, Butylene glycol, Dimethicone, Glycereth-26, Peg-100 stearate, Cetearyl alcohol, Glyceryl stearate, Propanediol, Narcissus tazetta bulb extract, Cucumis sativus fruit extract, Mimosa tenuiflora bark extract, Hordeum vulgare extract, Cucumis melo fruit extract, Persea gratissima oil, Whey protein, Caffeine, Thermus thermophillus ferment, Algae extract, Laminaria digitata extract, Artemia extract, Acetyl hexapeptide-8, Polygonum cuspidatum root extract, Ergothioneine, Trifluoroacetyl tripeptide-2, Trehalose, Sorbitol, Glycerin, Decarboxy carnosine hcl, Cholesterol, Isohexadecane, Acetyl glucosamine, Myristyl myristate, Cetearyl glucoside, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, Propylene glycol dicaprylate, Aminopropyl ascorbyl phosphate, Caprylyl glycol, Acrylates/c10-30 alkyl acrylate crosspolymer, Caprylic/capric triglyceride, Tocopheryl acetate, Linoleic acid, Polysorbate 80, Yeast extract, Propylene glycol dicaprate, Zinc pca, Helianthus annuus seedcake, Hexylene glycol, Acrylamide/sodium acryloyldimethyltaurate copolymer, Sodium hyaluronate, Myristyl alcohol, Tromethamine, Stearic acid, Potassium sulfate, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Citric acid, Maltodextrin, Aluminum hydroxide, Parfum, Potassium sorbate, Dextran, Disodium edta, Bht, Phenoxyethanol, Ci 42090, Ci 17200, Titanium dioxide

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Amazon USPrice as of 10/26/2026 16:28 GMT
$120.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Estée LauderResilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer CreamYOUR PRODUCTDarphinIdeal Resource Anti-Age & Radiance Eye Contour Radiance Repair CreamCliniqueSmart Night Custom-Repair Moisturizer For Very Dry Skin
Match—51%50%
Price$116.91——
Shared key ingredients—17 of 229 of 22
Key difference—Knotgrass ExtractAminopropyl Ascorbyl Phosphate
Irritancy Medium Medium Medium
Drying alcohol———
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 38 studies and safety reviews.

  1. 1
    Amended Safety Assessment of Triglycerides as Used in Cosmeticir-safety.org
  2. 2
    Safety Assessment of Alkyl Esters as Used in Cosmeticsjournals.sagepub.com
  3. 3
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  4. 4
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  5. 5
    Safety Assessment of Glycerin Ethoxylates as Used in Cosmeticscir-safety.org
  6. 6
    Celiac Disease & Skin Care Productsbadgut.org
Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer Cream
Estée LauderResilience Multi-Effect Night Tri-Peptide Face and Neck Moisturizer Cream
Buy on Amazon$120.00 · as of 10/26 16:28 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$120.00 · as of 10/26 16:28 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.