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E45 Eczema Repair Cream
E45

E45 Eczema Repair Cream

Efficacy75/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
Cera alba, Oenothera biennis oil + 11 more
Good evidence
What the product description says
“With omega fatty acids to help repair the skin barrier and keep it moisturised for 24 hours, this cream provides a protective layer that helps to lock moisture into the skin and helps keep irritants out to avoid triggering new flare-ups.”
Source: Feelunique

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glyceryl acrylate/acrylic acid copolymer.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, cera alba.

Cera albaKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.35–0.85%
Oenothera biennis oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can support skin barrier function~1.1–1.6%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.3–2%
Synthetic beeswaxKey activeEffect: HighHelps soften the upper layer of the skin~0.55–1.25%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–5.9%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.15–0.6%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~3.7–5.6%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.95–1.45%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~2.8–4.2%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~1.8–2.6%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~2–3.1%
Polyquaternium-51Effect: LowAn emollient that helps create a nice silky finish on the skin~0.05–0.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.35–0.8%

Can it cause trouble?

Irritancy
11 flagged ingredients
Low risk
We flag 11 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Peg-8Used to create a nice product consistencyMedium~2–3.1%est.
Hydrogenated coco-glyceridesHelps oil and water mix together while creating a nice finish on the skinMedium~1.4–2.2%est.
Oenothera biennis oilHelps soften the upper layer of the skin and can support skin barrier functionMedium~1.1–1.6%est.
Potassium sorbateA preservativeMedium~0.3–0.6%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.3–0.75%est.
Cera albaForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergenMedium~0.35–0.85%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.15–0.6%est.
Dimethylimidazolidinone rice starchUsed to create a thicker product consistencyMedium~0.15–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.45%est.
EthylhexylglycerinA preservativeMedium~0.1–0.45%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~3.7–5.6%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.9–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butyrospermum parkii butter~3.7–5.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Hydrogenated polyisobutene~2.8–4.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Peg-8~2–3.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Isononyl isononanoate~1.8–2.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Hydrogenated coco-glycerides~1.4–2.2%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together while creating a nice finish on the skin

More about Hydrogenated coco-glycerides
Dimethicone~1.3–2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Oenothera biennis oil~1.1–1.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-blemishAnti-oxidationAnti-inflammatory

Helps soften the upper layer of the skin and can support skin barrier function

More about Oenothera biennis oil
Cetyl alcohol~0.95–1.45%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Synthetic beeswax~0.55–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Synthetic beeswax
Cetyl hydroxyethylcellulose~0.45–1.1%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize formulations

More about Cetyl hydroxyethylcellulose
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Xanthan gum~0.35–0.85%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Potassium sorbate~0.3–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Tocopherol~0.35–0.8%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.3–0.75%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Cera alba~0.35–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Cera alba
Glyceryl acrylate/acrylic acid copolymer~0.15–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Dimethylimidazolidinone rice starch~0.15–0.5%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Dimethylimidazolidinone rice starch
Disodium edta~0.1–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ethylhexylglycerin~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Phenoxyethanol~0.1–0.4%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Hydrated silica~0.15–0.65%
Formula
Irritation risk
Low
Works for
Mattifying
More about Hydrated silica
Disodium phosphate~0.1–0.3%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Silica dimethyl silylate~0.1–0.35%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Silica dimethyl silylate
Sodium phosphate~0.05–0.2%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Sodium phosphate
Ascorbyl palmitate~0.05–0.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidation

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Polyquaternium-51~0.05–0.2%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps create a nice silky finish on the skin

More about Polyquaternium-51
Ingredient list view

Water, Glycerin, Butyrospermum parkii butter, Hydrogenated polyisobutene, Peg-8, Isononyl isononanoate, Hydrogenated coco-glycerides, Dimethicone, Oenothera biennis oil, Cetyl alcohol, Synthetic beeswax, Cetyl hydroxyethylcellulose, Sodium benzoate, Xanthan gum, Potassium sorbate, Tocopherol, Acrylates/c10-30 alkyl acrylate crosspolymer, Cera alba, Glyceryl acrylate/acrylic acid copolymer, Dimethylimidazolidinone rice starch, Disodium edta, Ethylhexylglycerin, Phenoxyethanol, Hydrated silica, Disodium phosphate, Silica dimethyl silylate, Sodium phosphate, Ascorbyl palmitate, Polyquaternium-51

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 7 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
  3. 3
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  4. 4
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  5. 5
    Vitamin E in dermatologyncbi.nlm.nih.gov
  6. 6
    Vitamin E and Skin Healthlpi.oregonstate.edu
E45 Eczema Repair Cream
E45Eczema Repair Cream
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As an Amazon Associate, WIMJ earns from qualifying purchases.