DEWYCEL F5 Ampule Cream

DEWYCEL F5 Ampule Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Niacinamide, Ceramide np + 19 more
Strong evidence
What the product description says
“DEWYCEL's Cica Plus Balm 2X, a moisturizing cream that reinforces the skin barrier to boost its resilience against external aggressors.”
Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.5%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.7–4%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.1–0.45%
Undaria pinnatifida extractKey activeEffect: HighA seaweed extract that helps attract water to the upper layer of the skin and might have an anti-oxidant effect~0.1–0.4%
Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.2–0.7%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.1–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–6.5%
Crithmum maritimum callus culture filtrateKey activeEffect: HighA plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties~0.15–0.55%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.1–0.35%
Laminaria japonica extractKey activeEffect: HighSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties~0.1–0.45%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–2.1%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.6%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.3%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.1–0.35%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.05–0.3%
Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~1.3–1.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1–1.6%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.1–0.45%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.45–1.1%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.15–0.55%
Pentaerythrityl tetraethylhexanoateEffect: Low, below effective doseUsed to create a nice product consistency while softening the upper layer of the skin~0.35–0.85%
Evens skin tone
Niacinamide
Strong evidence
What the product description says
“The brand is also renowned for its Turn On Cream, a brightening cream that reduces hyperpigmentation and helps bring out skin's natural glow. All”
Source: Yesstyle

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–2.1%
Anti-aging
Not advertised by the brand · Niacinamide, Adenosine + 1 more
Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–2.1%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.3%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.1–0.35%
Anti-blemish
Not advertised by the brand · Niacinamide
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–2.1%

Can it cause trouble?

Irritancy
2 strong irritants: Alcohol denat., Parfum
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~1.6–2.4%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.15%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.7–4%est.
1,2-hexanediolA preservativeMedium~1.1–1.7%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.45–1.1%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.1–0.3%est.
C12-20 alkyl glucosideHelps water and oil mix togetherMedium~0.1–0.35%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.1–0.35%est.
Myristic acidHelps oil and water mix together. Could be comedogenicMedium~0.15–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.25%est.
EthylhexylglycerinA preservativeMedium~0.05–0.2%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ecklonia cava extract—3/5~0.15–0.5%est.
Laminaria japonica extractSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties3/5~0.1–0.45%est.
Myristic acidHelps oil and water mix together. Could be comedogenic3/5~0.15–0.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–6.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dipropylene glycol~3.4–5.1%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Caprylic/capric triglyceride~2.7–4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
1,2-hexanediol~1.1–1.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Alcohol denat.~1.6–2.4%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Niacinamide~1.4–2.1%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Cyclohexasiloxane~1.3–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Glyceryl stearate~1–1.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
C14-22 alcohols~0.55–1.3%
Formula
Irritation risk
Low

A non-drying alcohol that helps stabilize product formulations

More about C14-22 alcohols
Pentylene glycol~0.45–1.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Pentaerythrityl tetraethylhexanoate~0.35–0.85%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product consistency while softening the upper layer of the skin

More about Pentaerythrityl tetraethylhexanoate
Vinyl dimethicone~0.2–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone
Ceramide np~0.15–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Hydrogenated lecithin~0.15–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Sodium hyaluronate~0.15–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Crithmum maritimum callus culture filtrate~0.15–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties

More about Crithmum maritimum callus culture filtrate
Ecklonia cava extract~0.15–0.5%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Ecklonia cava extract
Hizikia fusiforme extract~0.1–0.5%
Formula
Laminaria japonica extract~0.1–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Seaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties

More about Laminaria japonica extract
Undaria pinnatifida extract~0.1–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A seaweed extract that helps attract water to the upper layer of the skin and might have an anti-oxidant effect

More about Undaria pinnatifida extract
Hydrolyzed hyaluronic acid~0.1–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Adenosine~0.1–0.3%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Palmitic acid~0.1–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Stearic acid~0.15–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.1–0.3%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
C12-20 alkyl glucoside~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about C12-20 alkyl glucoside
Squalane~0.1–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Peg-100 stearate~0.15–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Carbomer~0.1–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Dimethicone/vinyl dimethicone crosspolymer~0.1–0.3%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
Tromethamine~0.1–0.3%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Polysorbate 60~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Propanediol~0.1–0.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Myristic acid~0.15–0.5%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Cleansing

Helps oil and water mix together. Could be comedogenic

More about Myristic acid
Sorbitan isostearate~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Glucose~0.1–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Hyaluronic acid~0.1–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Butylene glycol~0.05–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Disodium edta~0.05–0.25%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ethylhexylglycerin~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Parfum~0.05–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Glycerin, Dipropylene glycol, Caprylic/capric triglyceride, 1,2-hexanediol, Alcohol denat., Niacinamide, Cyclohexasiloxane, Glyceryl stearate, C14-22 alcohols, Pentylene glycol, Pentaerythrityl tetraethylhexanoate, Vinyl dimethicone, Ceramide np, Hydrogenated lecithin, Sodium hyaluronate, Crithmum maritimum callus culture filtrate, Ecklonia cava extract, Hizikia fusiforme extract, Laminaria japonica extract, Undaria pinnatifida extract, Hydrolyzed hyaluronic acid, Adenosine, Palmitic acid, Stearic acid, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, C12-20 alkyl glucoside, Squalane, Peg-100 stearate, Carbomer, Dimethicone/vinyl dimethicone crosspolymer, Tromethamine, Polysorbate 60, Propanediol, Myristic acid, Sorbitan isostearate, Glucose, Hyaluronic acid, Butylene glycol, Disodium edta, Ethylhexylglycerin, Parfum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DEWYCELF5 Ampule CreamYOUR PRODUCTNEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital CreamROUND LABPine Calming Cica Cream Plus 60mlThank You FarmerRice Pure Barrier Capsule Cream
Match—94%92%92%
Price$26.40$60.00+$33.60$18.99−$7.41—
Shared key ingredients—9 of 139 of 138 of 13
Key difference—Copper Tripeptide-1MadecassosideCopper Tripeptide-1
Irritancy Medium Medium Medium Medium
Drying alcohol Contains drying alcohol ———
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Product summary

Judging from the ingredient list, "DEWYCEL - F5 Ampule Cream" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. DEWYCEL - F5 Ampule Cream ticks this box. Glycerin, hyaluronic acid, hydrolyzed hyaluronic acid, sodium hyaluronate and glucose in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, vinyl dimethicone, caprylic/capric triglyceride, squalane and cyclohexasiloxane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (1.40% - 2.10%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
  • As a plus, this moisturizer also contains Ceramides (ceramide np 0.15% - 0.60%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Adenosine 0.10% - 0.30%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: stearic acid

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 26.40$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
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DEWYCEL F5 Ampule Cream
DEWYCELF5 Ampule Cream

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