PRODUCT REVIEW
Dermedicine Retinol High Potency Face Serum
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Product summary
What can the product work for?
Anti-aging
What does the product description say?
Our premium beauty serum combines Retinol with naturally derived ingredients Vitamin C & Caprylic Acid to be stimulating and boosting helping your complexion appear even, feel youthful and look brighter while helping to fade the appearance of fine lines and wrinkles, blotchiness and unevenness.
retinol
1.5% -
2.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
magnesium ascorbyl phosphate
2.7% -
4.1%
Irritation risk:
Concentration: Insufficient!
A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high
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Evens skin tone
What does the product description say?
Our premium beauty serum combines Retinol with naturally derived ingredients Vitamin C & Caprylic Acid to be stimulating and boosting helping your complexion appear even, feel youthful and look brighter while helping to fade the appearance of fine lines and wrinkles, blotchiness and unevenness.
retinol
1.5% -
2.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
magnesium ascorbyl phosphate
2.7% -
4.1%
Irritation risk:
Concentration: Insufficient!
A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high
Anti-blemish
retinol
1.5% -
2.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
sodium ascorbyl phosphate
3.8% -
5.8%
Irritation risk:
Concentration: Insufficient!
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
Exfoliation
retinol
1.5% -
2.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Moisturizing
glycerin
0.9% -
1.4%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
caprylic/capric triglyceride
1.2% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
ceramide np
0.1% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
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Anti-oxidation
retinol
1.5% -
2.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
sodium ascorbyl phosphate
3.8% -
5.8%
Irritation risk:
Concentration: Insufficient!
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
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Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Evens skin tone |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 1
Potential irritants
retinol
1.5% -
2.3%
Irritation risk:
Works for:
Exfoliation,
Anti-aging,
Anti-oxidation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Works for:
Evens skin tone,
Anti-oxidation,
Anti-aging
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Show more
Comodogenic ingredients
laureth-23
0.4% -
0.95%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing
Helps oil and water mix together
User reviews (0)
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Ingredients & concentrations
All ingredients
Key Actives
retinol
1.5% -
2.3%
Irritation risk:
Works for:
Exfoliation,
Anti-aging,
Anti-oxidation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Works for:
Evens skin tone,
Anti-oxidation,
Anti-aging
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Show more
Potential irritants
retinol
1.5% -
2.3%
Irritation risk:
Works for:
Exfoliation,
Anti-aging,
Anti-oxidation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Works for:
Evens skin tone,
Anti-oxidation,
Anti-aging
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Show more
Comodogenic ingredients
laureth-23
0.4% -
0.95%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing
Helps oil and water mix together
All ingredients
ascorbyl glucoside
6.6% -
9.9%
Irritation risk:
Works for:
Evens skin tone,
Anti-oxidation,
Anti-aging
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
sodium ascorbyl phosphate
3.8% -
5.8%
Irritation risk:
Works for:
Anti-blemish,
Anti-oxidation,
Anti-aging
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
Show more
Ingredient list view
Water, Ascorbyl glucoside, Sodium ascorbyl phosphate, Magnesium ascorbyl phosphate, Sodium hyaluronate, Retinol, Xanthan gum, Caprylic/capric triglyceride, Glycerin, Polysorbate 20, Cetyl palmitate, Laureth-23, Trideceth-6 phosphate, Phenoxyethanol, Triethanolamine, Ceramide np, Ethylhexylglycerin
Sources
- The Roles of Vitamin C in Skin Health
- Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
- Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris
- Sodium ascorbyl phosphate in topical microemulsions
- Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics
- Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphate
- Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
- Application of l-ascorbic acid and its derivatives (sodium ascorbyl phosphate and magnesium ascorbyl phosphate) in topical cosmetic formulations: stability studies
- Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial
- Topical L-ascorbic acid: percutaneous absorption studies
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Glycerol and the skin: holistic approach to its origin and functions
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems