Works for:
based on ingredients and %- Moisturizing
- Anti-oxidation
- Anti-aging
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
Based on the ingredient list, "DERMAFIRM - Ultra Soothing Hydra Cream R4" can work well for skin moisturization. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Acetyl hexapeptide-8, alanine, arginine, aspartic acid and betaine in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, hydrolyzed collagen, oenothera biennis oil, arginine and dimethiconol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- Another benefit is that this moisturizer contain ceramides (ceramide np 0.20% - 0.40%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- We like that this moisturizer contains peptides (palmitoyl oligopeptide 0.25% - 0.45%, acetyl hexapeptide-8 0.20% - 0.35% and copper tripeptide-1 0.20% - 0.35%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 29.50$ up to 40.30$ in the United States.
For a detailed price comparison: click here.
Works for
Moisturizing
What does the product description say?
Ultra Soothing Hydra Cream R4
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, arginine.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, dimethiconol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np, copper tripeptide-1, palmitoyl oligopeptide
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
Helps attract water to the upper layer of the skin and improves the product texture
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
An amino-acid that helps attract water to the upper layer of the skin
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Helps soften the upper layer of the skin and can support skin barrier function
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Might help neutralize free radicals in skin and might be helpful against hyperpigmentation
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
An emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A silicone that serves as an emollient. Helps create a nice non-greasy feels
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Helps to soften the upper layer of the skin and create a nice product texture
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-aging
This product contains acetyl hexapeptide-8, aspartic acid, copper tripeptide-1, lysine, palmitoyl oligopeptide, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-oxidation
This product contains antioxidants (cysteine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Might help neutralize free radicals in skin and might be helpful against hyperpigmentation
Helps soften the upper layer of the skin and can support skin barrier function
A plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritating
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 DERMAFIRM Ultra Soothing Hydra Cream R4 | Current | $29.50 | |
Evercell Deep Wrinkle Solution Cream Syringe Type | 52% | $14.10 | |
 The Saem Repair Rx Cream | 50% | $32.40 | |
KLAVUU Rejuve Pearlsation Multi Pearl Peptide Cream | 50% | $29.10 |
Key Actives
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Helps soften the upper layer of the skin and can support skin barrier function
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might help neutralize free radicals in skin and might be helpful against hyperpigmentation
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin and improves the product texture
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating
An amino-acid that helps attract water to the upper layer of the skin
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Potential irritants
A plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritating
A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating
Helps water and oil in the product mix well together and improves product texture
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Helps soften the upper layer of the skin and can support skin barrier function
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Comedogenic ingredients
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
All ingredients
A silicone that serves as an emollient. Helps create a nice non-greasy feels
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture
Helps attract water to the upper layer of the skin and improves the product texture
Helps water and oil in the product mix well together and improves product texture
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
Helps to soften the upper layer of the skin and create a nice product texture
Used to stabilize product formulations and create a nice product texture
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
A plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritating
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
An amino-acid that helps attract water to the upper layer of the skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
Helps soften the upper layer of the skin and can support skin barrier function
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Might help neutralize free radicals in skin and might be helpful against hyperpigmentation
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Ingredient list view
Water, Cyclohexasiloxane, Glycerin, Cetearyl alcohol, Butylene glycol, 1,2-hexanediol, Isododecane, Betaine, Cetearyl glucoside, Sodium polyacryloyldimethyl taurate, Dimethiconol, Hydrogenated polydecene, Dimethicone/vinyl dimethicone crosspolymer, Tocopherol, Hydrogenated phosphatidylcholine, Carbomer, Tromethamine, Ethylhexylglycerin, Dipotassium glycyrrhizate, Trideceth-10, Olea europaea fruit oil, Glyceryl acrylate/acrylic acid copolymer, Sodium hyaluronate, Glucose, Perilla ocymoides leaf extract, Sodium guaiazulene sulfonate, Centella asiatica extract, Glycine, Serine, Arginine, Hamamelis virginiana extract, Portulaca oleracea extract, Aspartic acid, Glutamic acid, Leucine, Lysine, Alanine, Proline, Phenylalanine, Threonine, Valine, Isoleucine, Tyrosine, Histidine, Disodium edta, Oenothera biennis oil, Copper tripeptide-1, Ppg-26-buteth-26, Peg-40 hydrogenated castor oil, Acetyl hexapeptide-8, Ceramide np, Palmitoyl oligopeptide, Oleic acid, Cysteine, Methionine, Hydrolyzed collagen
- Glycerol and the skin: holistic approach to its origin and functions
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Safety Assessment of Polyene Group as Used in Cosmetics
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Safety Assessment of Tromethamine as Used in Cosmetics
- Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
- Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Ethnomedicinal, Phytochemical and Pharmacological Investigations of Perilla frutescens (L.) Britt.
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Anti-Inflammatory Efficacy of Topical Preparations with 10% Hamamelis Distillate in a UV Erythema Test
- Anti-inflammatory activity of hamamelis distillate applied topically to the skin
- ASSESSMENT REPORT ON HAMAMELIS VIRGINIANA L., CORTEX HAMAMELIS VIRGINIANA L., FOLIUM HAMAMELIS VIRGINIANA L., FOLIUM ET CORTEX AUT RAMUNCULUS DESTILLATUM
- Portulaca oleracea (purslane)
- Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proof
- In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmness
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells
- Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trial
- Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases
- Safety Assessment of α-Amino Acids as Used in Cosmetics
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
- Amended Safety Assessment of Butyl Polyoxyalkylene Ethers as Used in Cosmetics
- Amended Safety Assessment of PEGylated Oils as Used in Cosmetics
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
- https://www.sciencedirect.com/science/article/pii/0168365995000887
- The Potential Uses of N-acetylcysteine in Dermatology: A Review