DERMAFIRM

DERMAFIRM Ultra Soothing Hydra Cream R4

Name: DERMAFIRM - Ultra Soothing Hydra Cream R4
Brand: DERMAFIRM

Efficacy100/100IrritancyMedium

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Works for

1 of 1 advertised claim delivered

Moisturizing

Palmitoyl oligopeptide, Copper tripeptide-1 + 34 more

Strong evidence

What the product description says

“Ultra Soothing Hydra Cream R4”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, dimethiconol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np, copper tripeptide-1, palmitoyl oligopeptide

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.15–0.3%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.15–0.3%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.15–0.3%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~1.4–1.7%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.15–0.3%

HistidineKey active· HumectantEffect: High~0.15–0.3%

DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.7–1%

Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.15–0.3%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.2–0.35%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.15–0.3%

LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.3%

Oenothera biennis oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can support skin barrier function~0.2–0.4%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–4.8%

CysteineKey activeEffect: HighMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.15–0.25%

Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.2–0.35%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.3%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.3%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.4%

TyrosineKey activeEffect: High~0.2–0.35%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.2–0.35%

IsododecaneKey active· Emollient, OcclusiveEffect: MediumAn emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture~1.7–2%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.2–0.4%

ProlineKey activeEffect: Medium~0.2–0.35%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.5–3.1%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.3–2.8%

Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~6.3–7.8%

Oleic acid· EmollientEffect: LowHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness~0.2–0.4%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~0.5–0.75%

Portulaca oleracea extract· HumectantEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.2–0.35%

Dipotassium glycyrrhizateUnder-dosedEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.25–0.45%

Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.4%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.6%

Anti-oxidation

Not advertised by the brand · Cysteine, Oenothera biennis oil + 4 more

Moderate evidence

This product contains antioxidants (cysteine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

CysteineKey activeEffect: MediumMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.15–0.25%

Oenothera biennis oilEffect: LowHelps soften the upper layer of the skin and can support skin barrier function~0.2–0.4%

Perilla ocymoides leaf extractEffect: LowA plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritating~0.2–0.35%

Portulaca oleracea extractEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.2–0.35%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.6%

Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.4%

Anti-aging

Not advertised by the brand · Lysine, Serine + 7 more

Moderate evidence

This product contains acetyl hexapeptide-8, aspartic acid, copper tripeptide-1, lysine, palmitoyl oligopeptide, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.3%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.15–0.3%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.15–0.3%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Can it cause trouble?

Irritancy

2 strong irritants: Perilla ocymoides leaf extract, Hamamelis virginiana extract

Medium risk

We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Perilla ocymoides leaf extractA plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritatingHigh~0.2–0.35%est.

Hamamelis virginiana extractA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~0.15–0.3%est.

1,2-hexanediolA preservativeMedium~0.7–1.05%est.

Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~1.1–1.4%est.

Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.8–1.2%est.

Hydrogenated phosphatidylcholineHelps oil and water mix togetherMedium~0.3–0.6%est.

EthylhexylglycerinA preservativeMedium~0.3–0.5%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.2–0.4%est.

Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.2–0.35%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.2–0.4%est.

Portulaca oleracea extractA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skinMedium~0.2–0.35%est.

Disodium edtaStabilizes the product formulationMedium~0.15–0.3%est.

Oenothera biennis oilHelps soften the upper layer of the skin and can support skin barrier functionMedium~0.2–0.4%est.

Ppg-26-buteth-26Helps oil and water mix togetherMedium~0.2–0.4%est.

Peg-40 hydrogenated castor oilHelps oil and water mix togetherMedium~0.2–0.4%est.

Oleic acidHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin drynessMedium~0.2–0.4%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.5–3.1%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Cyclohexasiloxane~6.3–7.8%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

Glycerin~3.9–4.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Cetearyl alcohol~2.5–3.1%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Butylene glycol~2.3–2.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~0.7–1.05%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Isododecane~1.7–2%

Key active

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin and can decrease moisture loss. Helps create a nice product texture

More about Isododecane

Betaine~1.4–1.7%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Cetearyl glucoside~1.1–1.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside

Sodium polyacryloyldimethyl taurate~0.8–1.2%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate

Dimethiconol~0.7–1%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol

Hydrogenated polydecene~0.5–0.75%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Dimethicone/vinyl dimethicone crosspolymer~0.45–0.7%

Formula

Irritation risk: Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer

Tocopherol~0.4–0.6%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Hydrogenated phosphatidylcholine~0.3–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Hydrogenated phosphatidylcholine

Carbomer~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Tromethamine~0.3–0.55%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Ethylhexylglycerin~0.3–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Dipotassium glycyrrhizate~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Trideceth-10~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Trideceth-10

Olea europaea fruit oil~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Glyceryl acrylate/acrylic acid copolymer~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer

Sodium hyaluronate~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Glucose~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Perilla ocymoides leaf extract~0.2–0.35%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin but solid research is lacking. Contains a number of volatile compounds and could be irritating

More about Perilla ocymoides leaf extract

Sodium guaiazulene sulfonate~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sodium guaiazulene sulfonate

Centella asiatica extract~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Glycine~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Serine~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Arginine~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Hamamelis virginiana extract~0.15–0.3%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana extract

Portulaca oleracea extract~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizing

A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin

More about Portulaca oleracea extract

Aspartic acid~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Glutamic acid~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Leucine~0.15–0.3%

Formula

Irritation risk: Low

More about Leucine

Lysine~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine

Alanine~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Proline~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Phenylalanine~0.2–0.35%

Formula

Irritation risk: Low

More about Phenylalanine

Threonine~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Valine~0.15–0.3%

Formula

Irritation risk: Low

More about Valine

Isoleucine~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Tyrosine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Histidine~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Disodium edta~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Oenothera biennis oil~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-inflammatoryAnti-blemishAnti-oxidation

Helps soften the upper layer of the skin and can support skin barrier function

More about Oenothera biennis oil

Copper tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Ppg-26-buteth-26~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together

More about Ppg-26-buteth-26

Peg-40 hydrogenated castor oil~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Peg-40 hydrogenated castor oil

Acetyl hexapeptide-8~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Ceramide np~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Palmitoyl oligopeptide~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide

Oleic acid~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

CleansingAnti-inflammatoryMoisturizing

Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness

More about Oleic acid

Cysteine~0.15–0.25%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Might help neutralize free radicals in skin and might be helpful against hyperpigmentation

More about Cysteine

Methionine~0.1–0.2%

Formula

Irritation risk: Low

More about Methionine

Hydrolyzed collagen~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen

Ingredient list view

Water, Cyclohexasiloxane, Glycerin, Cetearyl alcohol, Butylene glycol, 1,2-hexanediol, Isododecane, Betaine, Cetearyl glucoside, Sodium polyacryloyldimethyl taurate, Dimethiconol, Hydrogenated polydecene, Dimethicone/vinyl dimethicone crosspolymer, Tocopherol, Hydrogenated phosphatidylcholine, Carbomer, Tromethamine, Ethylhexylglycerin, Dipotassium glycyrrhizate, Trideceth-10, Olea europaea fruit oil, Glyceryl acrylate/acrylic acid copolymer, Sodium hyaluronate, Glucose, Perilla ocymoides leaf extract, Sodium guaiazulene sulfonate, Centella asiatica extract, Glycine, Serine, Arginine, Hamamelis virginiana extract, Portulaca oleracea extract, Aspartic acid, Glutamic acid, Leucine, Lysine, Alanine, Proline, Phenylalanine, Threonine, Valine, Isoleucine, Tyrosine, Histidine, Disodium edta, Oenothera biennis oil, Copper tripeptide-1, Ppg-26-buteth-26, Peg-40 hydrogenated castor oil, Acetyl hexapeptide-8, Ceramide np, Palmitoyl oligopeptide, Oleic acid, Cysteine, Methionine, Hydrolyzed collagen

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	DERMAFIRMUltra Soothing Hydra Cream R4YOUR PRODUCT	EvercellDeep Wrinkle Solution Cream Syringe Type	The SaemRepair Rx Cream	KLAVUURejuve Pearlsation Multi Pearl Peptide Cream
Match	—	52%	50%	50%
Price	$29.50	$14.10−$15.40	$32.40+$2.90	$29.10
Shared key ingredients	—	16 of 27	11 of 27	16 of 27
Key difference	—	Biotinoyl Tripeptide-1	Sh-Decapeptide-7	Niacinamide
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredient list, "DERMAFIRM - Ultra Soothing Hydra Cream R4" can work well for skin moisturization. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Acetyl hexapeptide-8, alanine, arginine, aspartic acid and betaine in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, hydrolyzed collagen, oenothera biennis oil, arginine and dimethiconol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

Another benefit is that this moisturizer contain ceramides (ceramide np 0.20% - 0.40%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
We like that this moisturizer contains peptides (palmitoyl oligopeptide 0.25% - 0.45%, acetyl hexapeptide-8 0.20% - 0.35% and copper tripeptide-1 0.20% - 0.35%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: centella asiatica extract, dipotassium glycyrrhizate and vitamin e

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.