Derma E Retinol Line Smoothing Hydro Gel Patches

Derma E Retinol Line Smoothing Hydro Gel Patches

Efficacy100/100IrritancyHigh

Works for

Anti-aging
Retinol, Adenosine + 2 more
Works well
What the product description says
“target wrinkles”
Source: Derma E

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, adenosine, bakuchiol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.05–0.15%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.4%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.1–0.5%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
Moisturizing
Acetyl hexapeptide-8, Glycerin + 10 more
Works well
What the product description says
“boost hydration”
Source: Derma E

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–6%
SucroseKey active· HumectantEffect: HighCan help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion~0.1–0.5%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.1–0.3%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.1–0.4%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.4%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.6–3.9%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.5–2.2%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.4%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.1–0.4%
Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.55%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.35%
Exfoliation
Side benefit · Retinol, Allantoin
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.05–0.15%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.35%
Anti-oxidation
Side benefit · Bakuchiol, Retinol + 2 more
Works well

This product contains antioxidants (bakuchiol, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.1–0.5%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.05–0.15%
Hibiscus sabdariffa flower extractEffect: LowA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals~0.15–0.55%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.1–0.4%
Evens skin tone
Side benefit the brand mentions · Retinol, Bakuchiol + 1 more
Works well
What the product description says
“more luminous”
Source: Derma E

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains bakuchiol. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.05–0.15%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.1–0.5%
Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.55%

Can it cause trouble?

Irritancy
4 strong irritants: Hibiscus sabdariffa flower extract, Illicium verum fruit extract + 2 more — patch-test recommended
High risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hibiscus sabdariffa flower extractA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicalsHigh~0.15–0.55%est.
Illicium verum fruit extractAnise fruit extract. Used as a fragrance. Can be irritatingHigh~0.1–0.5%est.
Rosa centifolia flower powder—High~0.15–0.7%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.05–0.15%est.
CarrageenanHelps thicken the product formula and create a nice product formulationMedium~3.5–5.3%est.
1,2-hexanediolA preservativeMedium~1.2–1.8%est.
Ceratonia siliqua gumUsed to stabilize product formulations and create thicker consistencyMedium~1.8–2.6%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.5–2.2%est.
Calcium chlorideHelps create a thicker product consistency. Might be irritatingMedium~0.45–1.05%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.35–0.8%est.
EthylhexylglycerinA preservativeMedium~0.1–0.35%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.1–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.4%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
CarrageenanHelps thicken the product formula and create a nice product formulation3/5~3.5–5.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4–6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Carrageenan~3.5–5.3%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5

Helps thicken the product formula and create a nice product formulation

More about Carrageenan
Butylene glycol~2.6–3.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
1,2-hexanediol~1.2–1.8%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Ceratonia siliqua gum~1.8–2.6%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulations and create thicker consistency

More about Ceratonia siliqua gum
Pentylene glycol~1.5–2.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Pinus sylvestris leaf extract~1.2–1.8%
Formula
Propanediol~1.1–1.6%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Cyamopsis tetragonoloba gum~0.85–1.25%
Formula
Calcium chloride~0.45–1.05%
Irritant · medium
Irritation risk
Medium

Helps create a thicker product consistency. Might be irritating

More about Calcium chloride
Polyglyceryl-10 laurate~0.35–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Allantoin~0.1–0.35%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Hibiscus sabdariffa flower extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

More about Hibiscus sabdariffa flower extract
Sucrose~0.1–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Can help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion

More about Sucrose
Potassium chloride~0.15–0.55%
Formula
Illicium verum fruit extract~0.1–0.5%
Irritant · high
Irritation risk
High

Anise fruit extract. Used as a fragrance. Can be irritating

More about Illicium verum fruit extract
Dipotassium glycyrrhizate~0.15–0.55%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Calcium lactate~0.15–0.55%
Formula
Rosa centifolia flower powder~0.15–0.7%
Irritant · high
Adenosine~0.1–0.4%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Arginine~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Ci 77491~0.1–0.35%
Formula
Irritation risk
Low

A red colorant made of iron oxide. Typically is not irritating

More about Ci 77491
Ethylhexylglycerin~0.1–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Bakuchiol~0.1–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatoryAnti-blemishEvens skin toneAnti-aging

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Cellulose gum~0.1–0.4%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Sodium phytate~0.1–0.35%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Caprylyl glycol~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium hyaluronate~0.1–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Lecithin~0.1–0.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Polysorbate 20~0.05–0.25%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Retinol~0.05–0.15%
Hero · Anti-aging, Evens skin toneIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Acetyl hexapeptide-8~0.05–0.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Ingredient list view

Water, Glycerin, Carrageenan, Butylene glycol, 1,2-hexanediol, Ceratonia siliqua gum, Pentylene glycol, Pinus sylvestris leaf extract, Propanediol, Cyamopsis tetragonoloba gum, Calcium chloride, Polyglyceryl-10 laurate, Allantoin, Hibiscus sabdariffa flower extract, Sucrose, Potassium chloride, Illicium verum fruit extract, Dipotassium glycyrrhizate, Calcium lactate, Rosa centifolia flower powder, Adenosine, Arginine, Ci 77491, Ethylhexylglycerin, Bakuchiol, Cellulose gum, Sodium phytate, Caprylyl glycol, Sodium hyaluronate, Lecithin, Polysorbate 20, Retinol, Acetyl hexapeptide-8

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Derma E
$16.95
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma ERetinol Line Smoothing Hydro Gel PatchesYOUR PRODUCTPETITFEEAura Quartz Lip Mask SHORT EXPIRY 25/03/2026Some By MiRetinol Intense Daily MaskPixiFortifEYE Firming Eye Patches
Match—79%73%73%
Price$16.95$1.05−$15.90$18.03+$1.08$22.80+$5.85
Shared key ingredients—7 of 97 of 97 of 9
Key difference—NiacinamideRetinalOctapeptide-7
Irritancy High Medium High Medium
Drying alcohol————
View product Shop Shop Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

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Derma E Retinol Line Smoothing Hydro Gel Patches
Derma ERetinol Line Smoothing Hydro Gel Patches

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.