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Derma E Hydrating Serum with Hyaluronic Acid
Derma E

Derma E Hydrating Serum with Hyaluronic Acid

Efficacy75/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Panthenol, Glycerin + 7 more
Works well
What the product description says
“Hydrating Serum with Hyaluronic Acid”
Source: Walgreens

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, allantoin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.95–1.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.8–5.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.1–4.6%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.1–3.2%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~1.6–2.4%
AllantoinKey active· HumectantEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.5–1.2%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.5–1.15%
TyrosineKey activeEffect: High~0.35–0.8%
GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.2–0.75%
Anti-aging
Ascorbyl palmitate
Not delivered
What the product description says
“Deeply moisturize and replump skin to diminish the look of fine lines and wrinkles.”
Source: Walgreens

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~1.3–1.9%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 5 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.1%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~2.7–4%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~1.3–1.9%est.
Potassium sorbateA preservativeMedium~0.1–0.35%est.
EthylhexylglycerinA preservativeMedium~0.05–0.2%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.1–4.6%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~2.7–4%est.
Alternatives
Cheaper, or higher on efficacy
Hyaluronic Acid Moisturizing Serum
CeraVe Hyaluronic Acid Moisturizing Serum
CheaperHigher efficacy · 100/10065% match
$23.15
Future Renew Serum
No7 Future Renew Serum
CheaperHigher efficacy · 100/10063% match
$25.97
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.8–5.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cetearyl alcohol~3.1–4.6%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Ceteareth-20~2.7–4%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Dimethicone~2.1–3.2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium hyaluronate~1.6–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Ascorbyl palmitate~1.3–1.9%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Ammonium acryloyldimethyltaurate/vp copolymer~1.1–1.7%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Panthenol~0.95–1.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Allantoin~0.5–1.2%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces rednessAnti-blemishReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Alanine~0.5–1.15%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Leucine~0.4–0.95%
Formula
Irritation risk
Low
More about Leucine
Tyrosine~0.35–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Glycine~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Valine~0.15–0.65%
Formula
Irritation risk
Low
More about Valine
Xanthan gum~0.1–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Potassium sorbate~0.1–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Phenoxyethanol~0.05–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Parfum~0.05–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Glycerin, Cetearyl alcohol, Ceteareth-20, Dimethicone, Sodium hyaluronate, Ascorbyl palmitate, Ammonium acryloyldimethyltaurate/vp copolymer, Panthenol, Allantoin, Alanine, Leucine, Tyrosine, Glycine, Valine, Xanthan gum, Potassium sorbate, Phenoxyethanol, Ethylhexylglycerin, Parfum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EHydrating Serum with Hyaluronic AcidYOUR PRODUCTCeraVeHyaluronic Acid Moisturizing SerumNo7Future Renew SerumSkintegraLunar Concentrate Serum
Match—65%63%62%
Price—$23.15$25.97—
Shared key ingredients—4 of 84 of 85 of 8
Key difference—Ceramide EopNiacinamideMadecassoside
Irritancy Medium Low Low Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
  5. 5
    Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
  6. 6
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
Derma E Hydrating Serum with Hyaluronic Acid
Derma EHydrating Serum with Hyaluronic Acid
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As an Amazon Associate, WIMJ earns from qualifying purchases.