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Product summary

Based on the ingredient list, "Derma E - Advanced Peptides & Collagen Moisturizer" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, panthenol and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, cetyl alcohol, macadamia ternifolia seed oil and glyceryl stearate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer includes a form of Retinoids (vitamin A) - retinyl palmitate 0.20% - 0.70%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • This moisturizer also contains Peptides (acetyl hexapeptide-8 0.60% - 1.40% and palmitoyl tripeptide-38 1.00% - 1.50%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • An effective concentration of Panthenol (pro-vitamin B5) - about 0.50% - 1.15%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: zinc oxide, allantoin, jojoba oil and vitamin e

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.


The product retails from 19.08$ up to 35.95$ in the United States and for 41.95A$ in Australia.

For a detailed price comparison: click here.