Derma E Advanced Peptides and Collagen Serum

Derma E Advanced Peptides and Collagen Serum

Efficacy87/100IrritancyMedium

Works for

Moisturizing
Acetyl hexapeptide-8, Palmitoyl tripeptide-38 + 7 more
Works well
What the product description says
“Moisture Replenishment: Panthenol (Provitamin B5) helps to replenish and retain moisture, conditioning your skin for a smooth and vibrant texture.”
Source: Derma E

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, ethylhexyl palmitate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tripeptide-38, panthenol

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.6–3.9%
Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–2%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.2–1.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–6.3%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.1–3.1%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.35–0.8%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~3.4–5%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~1.6–2.5%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.45%
Anti-aging
Acetyl hexapeptide-8, Palmitoyl tripeptide-38 + 2 more
May help
What the product description says
“This nourishing, double-action treatment formula addresses the appearance of deep lines and wrinkles, promoting smoother and younger-looking skin.”
Source: Derma E

This product contains acetyl hexapeptide-8, palmitoyl tripeptide-38. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.6–3.9%
Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–2%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~3.4–5%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.35–0.8%
Anti-oxidation
Not advertised by the brand · Camellia sinensis leaf extract, Pinus pinaster bark extract + 3 more
May help

This product contains antioxidants (camellia sinensis leaf extract, pinus pinaster bark extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~3.4–5%
Pinus pinaster bark extractKey activeEffect: MediumA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)~0.95–1.4%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.45–1.05%
Aesculus hippocastanum seed extractEffect: LowPlant extract. Might have some anti-oxidant properties. Can be irritating~0.15–0.65%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.35–0.8%

Can it cause trouble?

Irritancy
2 strong irritants: Hamamelis virginiana water, Parfum
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hamamelis virginiana waterA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~0.15–0.65%est.
Aesculus hippocastanum seed extractPlant extract. Might have some anti-oxidant properties. Can be irritatingHigh~0.15–0.65%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.01–0.05%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.1–3.1%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~1.6–2.5%est.
Pinus pinaster bark extractA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)Medium~0.95–1.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.45–1.05%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.35–0.8%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.1–0.3%est.
Potassium sorbateA preservativeMedium~0.05–0.2%est.
EthylhexylglycerinA preservativeMedium~0.05–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.35–0.8%est.

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.2–6.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Camellia sinensis leaf extract~3.4–5%
Key active
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingEvens skin toneMoisturizingAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Acetyl hexapeptide-8~2.6–3.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Caprylic/capric triglyceride~2.1–3.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydroxypropyl cyclodextrin~1.6–2.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Palmitoyl tripeptide-38~1.4–2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Panthenol~1.2–1.8%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Pinus pinaster bark extract~0.95–1.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)

More about Pinus pinaster bark extract
Acacia seyal gum extract~0.55–1.35%
Formula
Tocopheryl acetate~0.45–1.05%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ascorbyl palmitate~0.35–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Ethylhexyl palmitate~0.35–0.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Hamamelis virginiana water~0.15–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana water
Aesculus hippocastanum seed extract~0.15–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract. Might have some anti-oxidant properties. Can be irritating

More about Aesculus hippocastanum seed extract
Chamomilla recutita flower~0.15–0.65%
Formula
Allantoin~0.1–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Xanthan gum~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium citrate~0.1–0.3%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Microcrystalline cellulose~0.1–0.35%
Formula
Irritation risk
Low
Works for
Exfoliation
More about Microcrystalline cellulose
Cellulose gum~0.05–0.2%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Potassium sorbate~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium hydroxide~0.05–0.25%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Phenoxyethanol~0.05–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Parfum~0.01–0.05%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Glycerin, Camellia sinensis leaf extract, Acetyl hexapeptide-8, Caprylic/capric triglyceride, Hydroxypropyl cyclodextrin, Palmitoyl tripeptide-38, Panthenol, Pinus pinaster bark extract, Acacia seyal gum extract, Tocopheryl acetate, Ascorbyl palmitate, Ethylhexyl palmitate, Hamamelis virginiana water, Aesculus hippocastanum seed extract, Chamomilla recutita flower, Allantoin, Xanthan gum, Sodium citrate, Microcrystalline cellulose, Cellulose gum, Potassium sorbate, Sodium hydroxide, Phenoxyethanol, Ethylhexylglycerin, Parfum

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 11/7 09:07 GMT
$27.00
Buy
Derma E
$30.80
Buy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EAdvanced Peptides and Collagen SerumYOUR PRODUCTMedik8Liquid PeptidesBlissPro Youth SerumGeek GorgeousPower Peptides Serum
Match—61%57%55%
Price$30.80$68.00+$37.20—$16.53−$14.27
Shared key ingredients—4 of 74 of 74 of 7
Key difference—Copper Palmitoyl Heptapeptide-14Hexapeptide-9Copper Palmitoyl Heptapeptide-14
Irritancy Medium Low Medium Low
Drying alcohol————
View product Shop Shop Shop

More alternatives: eb5 Advanced Repair Peptide SerumEveline Cosmetics Serum Shot Multi Peptides & Collagen Serum Rejuvenation

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder
Derma E Advanced Peptides and Collagen Serum
Derma EAdvanced Peptides and Collagen Serum

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.